Stock Compensation (Tables)

3 Months Ended

Mar. 31, 2016

Disclosure of Compensation Related Costs, Share-based Payments [Abstract]

Total Compensation Cost from Share-Based Payments

The Company’s statements of operations included total compensation cost from awards under the Plans, the Inducement Awards, and purchases under the ESPP for the three-month periods ended March 31, 2016 and 2015, as follows:

In thousands	2016		2015
Compensation cost from:
Stock options	$	3,282	$	4,241
Stock and stock units	3,271		4,067
Purchases of common stock at a discount	166		126
	$	6,719	$	8,434
Compensation cost included in:
Research and development expense	$	3,765	$	3,816
Selling, general and administrative expense	2,954		4,618
	$	6,719	$	8,434

Stock Option Activity

Stock option activity under the Plans and Inducement Awards for the three-month period ended March 31, 2016 was as follows:

	Number of Shares		Weighted Average Exercise Price Per Share
Options outstanding, January 1, 2016	10,232,969		$	10.00
Granted	3,464,825		$	5.86
Forfeited	(201,147	)	$	10.50
Exercised	(23,600	)	$	3.84
Options outstanding, March 31, 2016	13,473,047		$	8.94

Stock and Stock Unit Activity

Stock and stock unit activity under the Plans and Inducement Awards for the three-month period ended March 31, 2016 was as follows:

	Number of Shares		Weighted Average Grant Date Fair Value
Outstanding, January 1, 2016	4,493,054		$	8.64
Granted / awarded	2,660,762		$	6.00
Forfeited	(353,964	)	$	8.96
Vested or restrictions lapsed	(1,329,120	)	$	7.99
Outstanding, March 31, 2016	5,470,732		$	7.50