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Fair Value Measurements and Investments - Schedule of Change in Valuation of Securities (Detail) - Bone Biologics Inc [Member] - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Fair Value Assets Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]      
Equity securities beginning balance $ 0 $ 219 $ 219
Fair value adjustments and impairments recognized in other income (expense), net 309 (219) 0
Equity securities ending balance $ 309 $ 0 $ 219