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Long-term Investments - Additional Information (Detail) - USD ($)
$ / shares in Units, shares in Thousands, $ in Thousands
12 Months Ended
Mar. 04, 2015
Dec. 31, 2016
Dec. 31, 2015
Debt Instrument [Line Items]      
Fair value of the debt security   $ 12,200  
Unrealized gain (loss) on debt securities   1,744 $ 3,348
Other-than-temporary impairment on debt securities   2,727  
Bone Biologics Inc [Member]      
Investments Equity Securities [Abstract]      
Value of common stock held   $ 2,500  
Warrants held for share purchases   458  
Weighted average exercise price of warrant   $ 1.18  
Warrants exercisable period   7 years  
Warrant expiration term   between 2020 and 2021  
Warrants expiration start year   2020  
Warrants expiration end year   2021  
eNeura Note [Member] | eNeura Inc [Member]      
Debt Instrument [Line Items]      
Non-refundable fees paid $ 300    
Accrued interest rate on promissory note 8.00%    
Maturity description of Promissory note   The eNeura Note will mature on March 4, 2019  
Debt Instrument, Maturity Date   Mar. 04, 2019  
eNeura Note [Member] | eNeura Inc [Member] | Convertible Debt Securities      
Debt Instrument [Line Items]      
Principal amount of promissory note $ 15,000    
eNeura Note [Member] | eNeura Inc [Member] | Debt Securities [Member]      
Debt Instrument [Line Items]      
Unrealized gain (loss) on debt securities   $ 1,744  
eNeura Note [Member] | eNeura Inc [Member] | Preferred Stock [Member]      
Debt Instrument [Line Items]      
Conversion price per share   $ 7.30  
eNeura Note [Member] | eNeura Inc [Member] | Minimum [Member]      
Debt Instrument [Line Items]      
Third party acquisition   50.00%