0001752724-21-112399.txt : 20210526
0001752724-21-112399.hdr.sgml : 20210526
20210526132418
ACCESSION NUMBER: 0001752724-21-112399
CONFORMED SUBMISSION TYPE: NPORT-P
PUBLIC DOCUMENT COUNT: 1
CONFORMED PERIOD OF REPORT: 20210331
FILED AS OF DATE: 20210526
PERIOD START: 20210930
FILER:
COMPANY DATA:
COMPANY CONFORMED NAME: TEKLA LIFE SCIENCES INVESTORS
CENTRAL INDEX KEY: 0000884121
IRS NUMBER: 043147016
STATE OF INCORPORATION: MA
FISCAL YEAR END: 0930
FILING VALUES:
FORM TYPE: NPORT-P
SEC ACT: 1940 Act
SEC FILE NUMBER: 811-06565
FILM NUMBER: 21964473
BUSINESS ADDRESS:
STREET 1: 100 FEDERAL STREET
STREET 2: 19TH FLOOR
CITY: BOSTON
STATE: MA
ZIP: 02110
BUSINESS PHONE: 6177728515
MAIL ADDRESS:
STREET 1: 100 FEDERAL STREET
STREET 2: 19TH FLOOR
CITY: BOSTON
STATE: MA
ZIP: 02110
FORMER COMPANY:
FORMER CONFORMED NAME: H&Q LIFE SCIENCES INVESTORS
DATE OF NAME CHANGE: 19920929
NPORT-P
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TEKLA LIFE SCIENCES INVESTORS
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5493007BYZPSOVVS0M04
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BOSTON
02110
617-772-8500
TEKLA LIFE SCIENCES INVESTORS
5493007BYZPSOVVS0M04
2021-09-30
2021-03-31
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0.00000000
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159.04000000
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Ionis Pharmaceuticals Inc
549300SI4ZGLG0BLUZ92
Ionis Pharmaceuticals Inc
462222100
98313.00000000
NS
USD
4420152.48000000
0.879315208082
Long
EC
CORP
US
N
1
N
N
N
Arrowhead Pharmaceuticals Inc
549300O3CSB8T7OZ3D66
Arrowhead Pharmaceuticals Inc
04280A100
52166.00000000
NS
USD
3459127.46000000
0.688135397146
Long
EC
CORP
US
N
1
N
N
N
KalVista Pharmaceuticals Inc
529900Q7IDA3WUGRZA51
KalVista Pharmaceuticals Inc
483497103
15797.00000000
NS
USD
405824.93000000
0.080732063968
Long
EC
CORP
US
N
1
N
N
N
Alnylam Pharmaceuticals Inc
529900S3ZI14OWRJII50
Alnylam Pharmaceuticals Inc
02043Q107
62136.00000000
NS
USD
8772981.84000000
1.745237610477
Long
EC
CORP
US
N
1
N
N
N
BioNTech SE
894500UZJ5LG1F8J1U58
BioNTech SE
09075V102
21672.00000000
NS
USD
2366365.68000000
0.470748767089
Long
EC
CORP
DE
N
1
N
N
N
Kura Oncology Inc
5493005QORQTZCZYOP39
Kura Oncology Inc
50127T109
95149.00000000
NS
USD
2689862.23000000
0.535102980539
Long
EC
CORP
US
N
1
N
N
N
Vertex Pharmaceuticals Inc
54930015RAQRRZ5ZGJ91
Vertex Pharmaceuticals Inc
92532F100
117437.00000000
NS
USD
25236036.93000000
5.020286328284
Long
EC
CORP
US
N
1
N
N
N
Gamida Cell Ltd
N/A
Gamida Cell Ltd
000000000
118142.00000000
NS
USD
955768.78000000
0.190134170137
Long
EC
CORP
IL
N
1
N
N
N
Exact Sciences Corp
549300VM3X1FYD4N9Z14
Exact Sciences Corp
30063P105
42839.00000000
NS
USD
5645323.42000000
1.123042419964
Long
EC
CORP
US
N
1
N
N
N
Mereo Biopharma Group PLC
213800U8JQHIJOS5AS09
Mereo Biopharma Group PLC
589492107
314585.00000000
NS
USD
1060151.45000000
0.210899351792
Long
EC
CORP
GB
N
1
N
N
N
Intercept Pharmaceuticals Inc
N/A
Intercept Pharmaceuticals Inc
45845P108
18630.00000000
NS
USD
429980.40000000
0.085537389628
Long
EC
CORP
US
N
1
N
N
N
Impact Biomedicines Milestone
N/A
Impact Biomedicines Milestone Preferred Stock
000000000
54327.05000000
NS
USD
2290971.70000000
0.455750399157
Long
CORP
US
Y
3
N
N
N
Dicerna Pharmaceuticals Inc
549300CTZMJMPH28WN39
Dicerna Pharmaceuticals Inc
253031108
21531.00000000
NS
USD
550547.67000000
0.109522226030
Long
EC
CORP
US
N
1
N
N
N
G1 Therapeutics Inc
529900TC35UPZQYRKW13
G1 Therapeutics Inc
3621LQ109
122990.00000000
NS
USD
2959139.40000000
0.588671157619
Long
EC
CORP
US
N
1
N
N
N
Genmab A/S
529900MTJPDPE4MHJ122
Genmab A/S
372303206
29963.00000000
NS
USD
983685.29000000
0.195687691630
Long
EC
CORP
DK
N
1
N
N
N
ARKUDA THERAPEUTICS,INC
N/A
ARKUDA THERAPEUTICS,INC SER A. SERIES A PREFERRED STOCK.
000000000
848333.00000000
NS
USD
2018184.21000000
0.401483902782
Long
EP
CORP
US
Y
3
N
N
N
ChemoCentryx Inc
529900YTTXUSFQTAKY40
ChemoCentryx Inc
16383L106
53779.00000000
NS
USD
2755635.96000000
0.548187561069
Long
EC
CORP
US
N
1
N
N
N
Nektar Therapeutics
5299005I24806IOIYE03
Nektar Therapeutics
640268108
37223.00000000
NS
USD
744460.00000000
0.148097832093
Long
EC
CORP
US
N
1
N
N
N
Theravance Biopharma Inc
5493007VTSXP4Z6MIW52
Theravance Biopharma Inc
000000000
141641.00000000
NS
USD
2890892.81000000
0.575094643062
Long
EC
CORP
KY
N
1
N
N
N
BioMarin Pharmaceutical Inc
NSLL8ITTRR0J5HEMR848
BioMarin Pharmaceutical Inc
09061G101
56850.00000000
NS
USD
4292743.50000000
0.853969328213
Long
EC
CORP
US
N
1
N
N
N
Pieris Pharmaceuticals Warrant Series B
254900AJDH8PAOOI5T33
Pieris Pharmaceuticals Warrant Series B
000000000
11911.00000000
NS
USD
5717.28000000
0.001137356974
N/A
DE
US
N
3
N/A
N/A
Call
Purchased
Pieris Pharmaceuticals Inc
Pieris Pharmaceuticals Inc
1.00000000
2.00000000
USD
2021-06-08
XXXX
4111.51000000
N
N
N
VECTIVBIO HOLDING AG
N/A
VECTIVBIO HOLDING AG SERIEES A2 PREFERRED
000000000
345010.00000000
NS
USD
397106.51000000
0.078997680521
Long
EP
CORP
US
Y
3
N
N
N
IO LIGHT HOLDINIGS, INC. SERIES A2 PREFERRED STOCK
N/A
IO LIGHT HOLDINIGS, INC. SERIES A2 PREFERRED STOCK
000000000
362887.00000000
NS
USD
1397368.97000000
0.277983122116
Long
EP
CORP
US
Y
3
N
N
N
Spectrum Pharmaceuticals Inc
549300COU30WSP3O5I07
Spectrum Pharmaceuticals Inc
84763A108
34880.00000000
NS
USD
113708.80000000
0.022620458815
Long
EC
CORP
US
N
1
N
N
N
Sage Therapeutics Inc
5493000JX4BJS9W6CN35
Sage Therapeutics Inc
78667J108
39422.00000000
NS
USD
2950736.70000000
0.586999581371
Long
EC
CORP
US
N
1
N
N
N
Curasen Therapeutics, Inc.
N/A
CURASEN THERAPEUTICS, INC. SERIES A PREFERRED STOCK
000000000
2719854.00000000
NS
USD
2999998.96000000
0.596799481849
Long
EP
CORP
US
Y
3
N
N
N
ARCA Biopharma, Inc.
529900TG7O4ESUDMGI54
Arca Biopharma, Inc. Warrants
000000000
18027.00000000
NS
USD
180.27000000
0.000035861693
N/A
DE
US
N
3
N/A
N/A
Call
Purchased
ARCA biopharma Inc
ARCA biopharma Inc
1.00000000
1.00000000
USD
2022-06-11
XXXX
-341.22000000
N
N
N
Adaptive Biotechnologies Corp
549300ZTF7OT1FW66Q96
Adaptive Biotechnologies Corp
00650F109
121513.00000000
NS
USD
4892113.38000000
0.973203914154
Long
EC
CORP
US
N
1
N
N
N
Travere Therapeutics Inc
N/A
Travere Therapeutics Inc
89422G107
70155.00000000
NS
USD
1751770.35000000
0.348485333207
Long
EC
CORP
US
N
1
N
N
N
Verona Pharma PLC
213800EVI6O6J3TIAL06
Verona Pharma PLC Wts Put Exp 27Apr22
000000000
371622.00000000
NS
7684.77000000
0.001528756114
N/A
DE
GB
N
3
N/A
N/A
Call
Purchased
Verona Pharma PLC
Verona Pharma PLC
1.00000000
2.85000000
USD
2022-04-27
XXXX
6253.42000000
N
N
N
PYXIS ONCOLOGY, INC.
N/A
PYXIS ONCOLOGY, INC. SERIES B PREFERRED STOCK
000000000
1166606.00000000
NS
USD
1920000.15000000
0.381951830633
Long
EP
CORP
US
Y
3
N
N
N
Afferent Milestone Interest
N/A
AFFERENT MILESTONE INTEREST COMMON STOCK
000000000
11232.03000000
NS
USD
291920.46000000
0.058072679888
Long
CORP
US
Y
3
N
N
N
Y-mAbs Therapeutics Inc
N/A
Y-mAbs Therapeutics Inc
984241109
62055.00000000
NS
USD
1876543.20000000
0.373306799222
Long
EC
CORP
US
N
1
N
N
N
Praxis Precision Medicines Inc
N/A
Praxis Precision Medicines Inc
74006W108
23594.00000000
NS
USD
772939.44000000
0.153763339068
Long
EC
CORP
US
N
1
N
N
N
Horizon Therapeutics Plc
N/A
Horizon Therapeutics Plc
000000000
202404.00000000
NS
USD
18629264.16000000
3.705979684047
Long
EC
CORP
IE
N
1
N
N
N
Seagen Inc
N/A
Seagen Inc
81181C104
95761.00000000
NS
USD
13297372.46000000
2.645289248395
Long
EC
CORP
US
N
1
N
N
N
ETHISMOS RESEARCH, INC. MILEST
N/A
ETHISMOS RESEARCH, INC. MILEST
000000000
820.00000000
NS
USD
0.00000000
0.000000
Long
CORP
US
Y
3
N
N
N
Ascendis Pharma A/S
549300B66JN3W3J8GH73
Ascendis Pharma A/S
04351P101
41459.00000000
NS
USD
5343235.92000000
1.062947177973
Long
EC
CORP
DK
N
1
N
N
N
Intellia Therapeutics Inc
5493002T5BCPE5DZC723
Intellia Therapeutics Inc
45826J105
19823.00000000
NS
USD
1590894.87000000
0.316481854411
Long
EC
CORP
US
N
1
N
N
N
Turning Point Therapeutics Inc
N/A
Turning Point Therapeutics Inc
90041T108
41021.00000000
NS
USD
3880176.39000000
0.771896020602
Long
EC
CORP
US
N
1
N
N
N
Apellis Pharmaceuticals Inc
254900HS0ZFRXXSB9D42
Apellis Pharmaceuticals Inc
03753U106
82121.00000000
NS
USD
3523812.11000000
0.701003323475
Long
EC
CORP
US
N
1
N
N
N
Biogen Inc
W8J5WZB5IY3K0NDQT671
Biogen Inc
09062X103
67462.00000000
NS
USD
18872494.50000000
3.754366281115
Long
EC
CORP
US
N
1
N
N
N
Trillium Therapeutics Inc
N/A
Trillium Therapeutics Inc
89620X506
157719.00000000
NS
USD
1693902.06000000
0.336973407387
Long
EC
CORP
CA
N
1
N
N
N
Madrigal Pharmaceuticals Inc
549300CHIMT2EUSNJB60
Madrigal Pharmaceuticals Inc
558868105
4060.00000000
NS
USD
474898.20000000
0.094473032647
Long
EC
CORP
US
N
1
N
N
N
United Therapeutics Corp
5299005C4HZL4UWROC14
United Therapeutics Corp
91307C102
20511.00000000
NS
USD
3430874.97000000
0.682515038067
Long
EC
CORP
US
N
1
N
N
N
ACADIA Pharmaceuticals Inc
529900O3044NO0PEA039
ACADIA Pharmaceuticals Inc
004225108
111776.00000000
NS
USD
2883820.80000000
0.573687785273
Long
EC
CORP
US
N
1
N
N
N
Syneos Health Inc
549300F1ZGKDS8P6GU13
Syneos Health Inc
87166B102
91070.00000000
NS
USD
6907659.50000000
1.374163013173
Long
EC
CORP
US
N
1
N
N
N
Endo International PLC
5493007TBMWZWGZIB256
Endo International PLC
000000000
29100.00000000
NS
USD
215631.00000000
0.042896171227
Long
EC
CORP
IE
N
1
N
N
N
OCULIS SA
N/A
OCULIS SA SERIES B2 PREFERRED PREFERRED STOCK
000000000
117704.00000000
NS
1036876.16000000
0.206269123183
Long
EP
CORP
CH
Y
3
N
N
N
Moderna Inc
549300EI6OKH5K5Q2G38
Moderna Inc
60770K107
172282.00000000
NS
USD
22560327.90000000
4.487998889530
Long
EC
CORP
US
N
1
N
N
N
Iovance Biotherapeutics Inc
549300220Z2GHH33XL82
Iovance Biotherapeutics Inc
462260100
138993.00000000
NS
USD
4400518.38000000
0.875409333159
Long
EC
CORP
US
N
1
N
N
N
Verona Pharma PLC
213800EVI6O6J3TIAL06
Verona Pharma PLC
925050106
315800.00000000
NS
USD
2640088.00000000
0.525201232215
Long
EC
CORP
GB
N
1
N
N
N
Atreca Inc
549300B5CQV1OOXFLU71
Atreca Inc
04965G109
48919.00000000
NS
USD
749928.27000000
0.149185652704
Long
EC
CORP
US
N
1
N
N
N
CRISPR Therapeutics AG
506700O6IRRIQLT3W370
CRISPR Therapeutics AG
000000000
51536.00000000
NS
USD
6279661.60000000
1.249233362757
Long
EC
CORP
CH
N
1
N
N
N
Denali Therapeutics Inc
549300ZTQ2HO18L3Q830
Denali Therapeutics Inc
24823R105
56397.00000000
NS
USD
3220268.70000000
0.640618452606
Long
EC
CORP
US
N
1
N
N
N
Illumina Inc
SQ95QG8SR5Q56LSNF682
Illumina Inc
452327109
71882.00000000
NS
USD
27607000.92000000
5.491949852033
Long
EC
CORP
US
N
1
N
N
N
Sutro Biopharma Inc
5493005U6P15VD25P851
Sutro Biopharma Inc
869367102
172491.00000000
NS
USD
3925895.16000000
0.780991003171
Long
EC
CORP
US
N
1
N
N
N
INVETX, INC.
N/A
INVETX, INC. SERIES A PREFERRED STOCK
000000000
3229167.00000000
NS
USD
1550000.16000000
0.308346537678
Long
EP
CORP
US
Y
3
N
N
N
Mirati Therapeutics Inc
529900GYRW59IDQV6N54
Mirati Therapeutics Inc
60468T105
28691.00000000
NS
USD
4914768.30000000
0.977710730556
Long
EC
CORP
US
N
1
N
N
N
Jounce Therapeutics Inc
5493004MZJQIV2K8ZT61
Jounce Therapeutics Inc
481116101
120324.00000000
NS
USD
1235727.48000000
0.245827258477
Long
EC
CORP
US
N
1
N
N
N
Nkarta Inc
N/A
Nkarta Inc
65487U108
28988.00000000
NS
USD
953705.20000000
0.189723655503
Long
EC
CORP
US
N
1
N
N
N
Rainier Therapeutics Series A PREFERRED STOCK
N/A
Rainier Therapeutics Series A PREFERRED STOCK
000000000
1153847.00000000
NS
USD
115.38000000
0.000022952916
Long
EP
CORP
US
Y
3
N
N
N
ARCA biopharma Inc
529900TG7O4ESUDMGI54
ARCA biopharma Inc
00211Y506
32461.00000000
NS
USD
118482.65000000
0.023570136213
Long
EC
CORP
US
N
1
N
N
N
Molecular Templates Inc
529900VZKP6N0B8U5F61
Molecular Templates Inc
608550109
95811.00000000
NS
USD
1209134.82000000
0.240537094740
Long
EC
CORP
US
N
1
N
N
N
Guardant Health Inc
254900M8C3E5VC8BR186
Guardant Health Inc
40131M109
61400.00000000
NS
USD
9372710.00000000
1.864543470216
Long
EC
CORP
US
N
1
N
N
N
Zogenix Inc
54930089H3HF4C32SK78
Zogenix Inc
98978L204
37281.00000000
NS
USD
727725.12000000
0.144768708368
Long
EC
CORP
US
N
1
N
N
N
Precision BioSciences Inc
549300I5QGRS3BLHZH41
Precision BioSciences Inc
74019P108
19832.00000000
NS
USD
205261.20000000
0.040833273423
Long
EC
CORP
US
N
1
N
N
N
Intra-Cellular Therapies Inc
5299002U2KGF193IJA20
Intra-Cellular Therapies Inc
46116X101
77580.00000000
NS
USD
2632289.40000000
0.523649831531
Long
EC
CORP
US
N
1
N
N
N
Incyte Corp
549300Z4WN6JVZ3T4680
Incyte Corp
45337C102
25486.00000000
NS
USD
2071247.22000000
0.412039898733
Long
EC
CORP
US
N
1
N
N
N
THEROX MILESTONE INTEREST
N/A
THEROX MILESTONE INTEREST
000000000
62.40000000
NS
USD
1726.61000000
0.000343480103
Long
EC
CORP
US
Y
3
N
N
N
Reata Pharmaceuticals Inc
5299005F094GH9QDDD80
Reata Pharmaceuticals Inc
75615P103
12440.00000000
NS
USD
1240268.00000000
0.246730518784
Long
EC
CORP
US
N
1
N
N
N
HOTSPOT THERAPEUTICS, INC. SERIES B PREFERRED STOCK
N/A
HOTSPOT THERAPEUTICS, INC. SERIES B PREFERRED STOCK
000000000
645834.00000000
NS
USD
1550001.60000000
0.308346824142
Long
EP
CORP
US
Y
3
N
N
N
Fate Therapeutics Inc
549300L14Q4UHOODLA90
Fate Therapeutics Inc
31189P102
66790.00000000
NS
USD
5506835.50000000
1.095492570780
Long
EC
CORP
US
N
1
N
N
N
TCR2 Therapeutics Inc
5493007TR1ORJAZ8YK34
TCR2 Therapeutics Inc
87808K106
76396.00000000
NS
USD
1686823.68000000
0.335565282394
Long
EC
CORP
US
N
1
N
N
N
Amgen Inc
62QBXGPJ34PQ72Z12S66
Amgen Inc
031162100
115240.00000000
NS
USD
28672864.40000000
5.703985516401
Long
EC
CORP
US
N
1
N
N
N
Karuna Therapeutics Inc
N/A
Karuna Therapeutics Inc
48576A100
28463.00000000
NS
USD
3422106.49000000
0.680770696022
Long
EC
CORP
US
N
1
N
N
N
PRA Health Sciences Inc
549300R1HR1VWWHIAK47
PRA Health Sciences Inc
69354M108
27493.00000000
NS
USD
4215501.69000000
0.838603365491
Long
EC
CORP
US
N
1
N
N
N
Allakos Inc
549300S6ZD1W6BPMDY37
Allakos Inc
01671P100
53427.00000000
NS
USD
6132351.06000000
1.219928401284
Long
EC
CORP
US
N
1
N
N
N
Ovid therapeutics Inc
549300H36NUI4L6U8F17
Ovid therapeutics Inc
690469101
111820.00000000
NS
USD
449516.40000000
0.089423749201
Long
EC
CORP
US
N
1
N
N
N
Replimune Group Inc
549300AY704NEIRC4K64
Replimune Group Inc
76029N106
76500.00000000
NS
USD
2334015.00000000
0.464313141838
Long
EC
CORP
US
N
1
N
N
N
Medpace Holdings Inc
549300H8TYEUVTW14A54
Medpace Holdings Inc
58506Q109
5822.00000000
NS
USD
955099.10000000
0.190000948531
Long
EC
CORP
US
N
1
N
N
N
Fixed Income Clearing Corp
549300H47WTHXPU08X20
FIXED INC CLEARING CORP.REPO
000000000
1047000.00000000
PA
USD
1047000.00000000
0.208283091370
Long
RA
CORP
US
N
2
Repurchase
N
0.00000000
2021-04-01
948000.00000000
USD
1068023.23692000
USD
UST
N
N
N
Corbus Pharmaceuticals Holdings Inc
529900MX6XCNZC7MM155
Corbus Pharmaceuticals Holdings Inc
21833P103
154310.00000000
NS
USD
303990.70000000
0.060473851713
Long
EC
CORP
US
N
1
N
N
N
AMPHIVENA THERAPEUTICS, INC. SERIES C PREFERRED STOCK
N/A
AMPHIVENA THERAPEUTICS, INC. SERIES C PREFERRED STOCK
000000000
225416.31000000
NS
USD
808847.82000000
0.160906709071
Long
EP
CORP
US
Y
3
N
N
N
Pieris Pharmaceuticals Inc
254900AJDH8PAOOI5T33
Pieris Pharmaceuticals Inc
720795103
266757.00000000
NS
USD
685565.49000000
0.136381757014
Long
EC
CORP
US
N
1
N
N
N
Blueprint Medicines Corp
5299004CC60O9T5HVM83
Blueprint Medicines Corp
09627Y109
45530.00000000
NS
USD
4426881.90000000
0.880653913336
Long
EC
CORP
US
N
1
N
N
N
Morphic Holding Inc
549300RWWOUFLHTY1224
Morphic Holding Inc
61775R105
28213.00000000
NS
USD
1785318.64000000
0.355159202884
Long
EC
CORP
US
N
1
N
N
N
Bridgebio Pharma Inc
54930028YG89VTY2J114
Bridgebio Pharma Inc
10806X102
23337.00000000
NS
USD
1437559.20000000
0.285978294368
Long
EC
CORP
US
N
1
N
N
N
Xenon Pharmaceuticals Inc
549300XV44Q9Z1MIPQ03
Xenon Pharmaceuticals Inc
98420N105
51589.00000000
NS
USD
923443.10000000
0.183703518216
Long
EC
CORP
CA
N
1
N
N
N
Deciphera Pharmaceuticals Inc
529900QR4WAPYY0CBF25
Deciphera Pharmaceuticals Inc
24344T101
84072.00000000
NS
USD
3769788.48000000
0.749936197159
Long
EC
CORP
US
N
1
N
N
N
NEXGEL, INC COMMON STOCK
N/A
NEXGEL, INC COMMON STOCK
000000000
44550.00000000
NS
USD
138.11000000
0.000027474668
Long
EC
CORP
US
N
3
N
N
N
NEUROVANCE MILESTONE INTEREST
N/A
NEUROVANCE MILESTONE INTEREST
000000000
34054.99000000
NS
USD
4283436.64000000
0.852117884496
Long
CORP
US
Y
3
N
N
N
Ardelyx Inc
549300F542QR4SXHCY32
Ardelyx Inc
039697107
289336.00000000
NS
USD
1915404.32000000
0.381037567329
Long
EC
CORP
US
N
1
N
N
N
Jazz Pharmaceuticals PLC
635400GAUMJCLEZRRV50
Jazz Pharmaceuticals PLC
000000000
25203.00000000
NS
USD
4142617.11000000
0.824104200605
Long
EC
CORP
IE
N
1
N
N
N
Sarepta Therapeutics Inc
549300IKDPIED8J8IG21
Sarepta Therapeutics Inc
803607100
35334.00000000
NS
USD
2633443.02000000
0.523879324883
Long
EC
CORP
US
N
1
N
N
N
Argenx SE
7245009C5FZE6G9ODQ71
Argenx SE
04016X101
23128.00000000
NS
USD
6369219.92000000
1.267049488590
Long
EC
CORP
NL
N
1
N
N
N
INNOVACARE INC COMMON STOCK
N/A
INNOVACARE INC COMMON STOCK
457ESC010
148148.00000000
NS
USD
70414.74000000
0.014007831638
Long
EC
CORP
US
Y
3
N
N
N
Helix Acquisition Corp
N/A
Helix Acquisition Corp
000000000
78403.00000000
NS
USD
802454.71000000
0.159634907051
Long
EC
CORP
KY
N
1
N
N
N
TETRAPHASE PHARMACEUTICALS INC
N/A
TETRAPHASE PHARMACEUTICALS INC
881CVR013
14218.00000000
NS
USD
2843.60000000
0.000565686531
N/A
DE
US
N
2
N/A
N/A
Tetraphase Pharmaceuticals Inc
Tetraphase Pharmaceuticals Inc
2099-12-31
XXXX
0.00000000
N
N
N
DYNACURE SERIES C PREFERRED STOCK
N/A
DYNACURE SERIES C PREFERRED STOCK
000000000
103675.00000000
NS
2579920.68000000
0.513231952932
Long
EP
CORP
FR
Y
3
N
N
N
Zai Lab Ltd
549300P2UYQ9U5LY1T58
Zai Lab Ltd
98887Q104
11502.00000000
NS
USD
1534711.86000000
0.305305186784
Long
EC
CORP
KY
N
1
N
N
N
Heron Therapeutics Inc
549300DR2I1DOPD2IX53
Heron Therapeutics Inc
427746102
40585.00000000
NS
USD
657882.85000000
0.130874760035
Long
EC
CORP
US
N
1
N
N
N
I-Mab
549300L1A5T19703RR64
I-Mab
44975P103
26109.00000000
NS
USD
1265503.23000000
0.251750644587
Long
EC
CORP
KY
N
1
N
N
N
Ultragenyx Pharmaceutical Inc
529900EV44GVDN1DCX77
Ultragenyx Pharmaceutical Inc
90400D108
29770.00000000
NS
USD
3389612.20000000
0.674306501969
Long
EC
CORP
US
N
1
N
N
N
Insmed Inc
529900Q55QAG41CCAC11
Insmed Inc
457669307
37238.00000000
NS
USD
1268326.28000000
0.252312243041
Long
EC
CORP
US
N
1
N
N
N
RALLYBIO HOLDINGS, LLC SERIES B PREFERRED STOCK
N/A
RALLYBIO HOLDINGS, LLC SERIES B PREFERRED STOCK
000000000
2229766.00000000
NS
USD
3100043.67000000
0.616701699112
Long
EP
CORP
US
Y
3
N
N
N
Clearside Biomedical Inc
529900GQSUZO5HQ9DS29
Clearside Biomedical Inc
185063104
165330.00000000
NS
USD
408365.10000000
0.081237388190
Long
EC
CORP
US
N
1
N
N
N
THERACHON MILESTONE INTEREST
N/A
THERACHON MILESTONE INTEREST
000000000
14097.79000000
NS
USD
585481.22000000
0.116471669953
Long
EP
CORP
US
Y
3
N
N
N
Arcutis Biotherapeutics Inc
N/A
Arcutis Biotherapeutics Inc
03969K108
44764.00000000
NS
USD
1295022.52000000
0.257623012282
Long
EC
CORP
US
N
1
N
N
N
Vir Biotechnology Inc
N/A
Vir Biotechnology Inc
92764N102
25600.00000000
NS
USD
1312512.00000000
0.261102251022
Long
EC
CORP
US
N
1
N
N
N
CARIBOU BIOSCIENCES
N/A
CARIBOU BIOSCIENCES SERIES C PREFERRED STOCK
000000000
79099.00000000
NS
USD
1365011.44000000
0.271546134172
Long
EP
CORP
US
Y
3
N
N
N
Arvinas Inc
N/A
Arvinas Inc
04335A105
34619.00000000
NS
USD
2288315.90000000
0.455222072286
Long
EC
CORP
US
N
1
N
N
N
BeiGene Ltd
549300JFUK6FRD5MH739
BeiGene Ltd
07725L102
12109.00000000
NS
USD
4214900.72000000
0.838483812588
Long
EC
CORP
KY
N
1
N
N
N
Cogent Biosciences Inc
N/A
Cogent Biosciences Inc
19240Q201
168782.00000000
NS
USD
1481905.96000000
0.294800338556
Long
EC
CORP
US
N
1
N
N
N
Neurocrine Biosciences Inc
549300FECER0XBN49756
Neurocrine Biosciences Inc
64125C109
71328.00000000
NS
USD
6936648.00000000
1.379929789099
Long
EC
CORP
US
N
1
N
N
N
Exelixis Inc
254900PJQB59O2O95R37
Exelixis Inc
30161Q104
229590.00000000
NS
USD
5186438.10000000
1.031754881249
Long
EC
CORP
US
N
1
N
N
N
Affimed NV
5493004V4FSXT1D04610
Affimed NV
000000000
104312.00000000
NS
USD
825107.92000000
0.164141383277
Long
EC
CORP
NL
N
1
N
N
N
Editas Medicine Inc
5299000AON4Q9NT2JE42
Editas Medicine Inc
28106W103
15190.00000000
NS
USD
637980.00000000
0.126915421807
Long
EC
CORP
US
N
1
N
N
N
AMPHIVENA THERAPEUTICS, INC. SERIES B PREFERRED STOCK
N/A
AMPHIVENA THERAPEUTICS, INC. SERIES B PREFERRED STOCK
000000000
140000.00000000
NS
USD
2100000.00000000
0.417759782117
Long
EP
CORP
US
Y
3
N
N
N
Forma Therapeutics Holdings Inc
N/A
Forma Therapeutics Holdings Inc
34633R104
53186.00000000
NS
USD
1490271.72000000
0.296464566211
Long
EC
CORP
US
N
1
N
N
N
PRIOTHERA LIMITED
N/A
PRIOTHERA LIMITED SERIES A PREFERRED STOCK
000000000
41067.00000000
NS
481592.71000000
0.095804793142
Long
EP
CORP
IE
Y
3
N
N
N
Regeneron Pharmaceuticals Inc
549300RCBFWIRX3HYQ56
Regeneron Pharmaceuticals Inc
75886F107
44812.00000000
NS
USD
21202349.68000000
4.217851896526
Long
EC
CORP
US
N
1
N
N
N
VYNE Therapeutics Inc
N/A
VYNE Therapeutics Inc
92941V209
40620.00000000
NS
USD
278043.90000000
0.055312170992
Long
EC
CORP
US
N
1
N
N
N
Pieris Pharmaceuticals Warrant Series A
254900AJDH8PAOOI5T33
Pieris Pharmaceuticals Warrant Series A
000000000
23821.00000000
NS
USD
2858.52000000
0.000568654615
N/A
DE
US
N
3
N/A
N/A
Call
Purchased
Pieris Pharmaceuticals Inc
Pieris Pharmaceuticals Inc
1.00000000
3.00000000
USD
2021-06-08
XXXX
-352.89000000
N
N
N
VECTIVBIO HOLDING AG
N/A
VECTIVBIO HOLDING AG
000000000
375000.00000000
NS
USD
296250.00000000
0.058933969263
Long
EC
CORP
US
Y
3
N
N
N
Arena Pharmaceuticals Inc
529900CVGQMPJ3A3NI85
Arena Pharmaceuticals Inc
040047607
67473.00000000
NS
USD
4681951.47000000
0.931395726663
Long
EC
CORP
US
N
1
N
N
N
Aurinia Pharmaceuticals Inc
5299008YP2BW4570ML28
Aurinia Pharmaceuticals Inc
05156V102
127109.00000000
NS
USD
1650510.37000000
0.328341358359
Long
EC
CORP
CA
N
1
N
N
N
Personalis Inc
549300EZ2NYFK7H0US48
Personalis Inc
71535D106
58816.00000000
NS
USD
1447461.76000000
0.287948242610
Long
EC
CORP
US
N
1
N
N
N
Alkermes PLC
N/A
Alkermes PLC
000000000
60092.00000000
NS
USD
1122518.56000000
0.223306242404
Long
EC
CORP
IE
N
1
N
N
N
Alexion Pharmaceuticals Inc
M1YXUUZR0EIMU8T0EM75
Alexion Pharmaceuticals Inc
015351109
59698.00000000
NS
USD
9128421.18000000
1.815946306303
Long
EC
CORP
US
N
1
N
N
N
Rainier Therapeutics Series B PREFERRED STOCK
N/A
Rainier Therapeutics Series B PREFERRED STOCK
000000000
668449.00000000
NS
USD
124331.51000000
0.024733668822
Long
EP
CORP
US
Y
3
N
N
N
Amicus Therapeutics Inc
549300MRD1SMUTNBPQ53
Amicus Therapeutics Inc
03152W109
217266.00000000
NS
USD
2146588.08000000
0.427027699332
Long
EC
CORP
US
N
1
N
N
N
Scholar Rock Holding Corp
549300Z1FLPGL4OWJ459
Scholar Rock Holding Corp
80706P103
17193.00000000
NS
USD
870997.38000000
0.173270321759
Long
EC
CORP
US
N
1
N
N
N
Galera Therapeutics Inc
N/A
Galera Therapeutics Inc
36338D108
145858.00000000
NS
USD
1286467.56000000
0.255921146460
Long
EC
CORP
US
N
1
N
N
N
Novavax Inc
529900J4GJHPEPQ23205
Novavax Inc
670002401
36998.00000000
NS
USD
6708107.38000000
1.334465465472
Long
EC
CORP
US
N
1
N
N
N
Bellicum Pharmaceuticals Inc
529900HBXNLX2TBQZQ65
Bellicum Pharmaceuticals Inc
079481404
6000.00000000
NS
USD
22560.00000000
0.004487933659
Long
EC
CORP
US
N
1
N
N
N
uniQure NV
N/A
uniQure NV
000000000
42765.00000000
NS
USD
1440752.85000000
0.286613617477
Long
EC
CORP
NL
N
1
N
N
N
Cymabay Therapeutics Inc
549300YT9GNL852E7F84
Cymabay Therapeutics Inc
23257D103
32636.00000000
NS
USD
148167.44000000
0.029475427357
Long
EC
CORP
US
N
1
N
N
N
Cercacor Laboratories Inc
N/A
CERCACOR LABORATORIES INC COMMON STOCK
000000000
130000.00000000
NS
USD
1429689.82000000
0.284412813190
Long
EC
CORP
US
Y
3
N
N
N
IDEXX Laboratories Inc
OGMTXK0LUU1HKV2P0J84
IDEXX Laboratories Inc
45168D104
8329.00000000
NS
USD
4075462.99000000
0.810745014634
Long
EC
CORP
US
N
1
N
N
N
Black Diamond Therapeutics Inc
N/A
Black Diamond Therapeutics Inc
09203E105
41586.00000000
NS
USD
1008876.36000000
0.200699032541
Long
EC
CORP
US
N
1
N
N
N
Gilead Sciences Inc
549300WTZWR07K8MNV44
Gilead Sciences Inc
375558103
551520.00000000
NS
USD
35644737.60000000
7.090922768299
Long
EC
CORP
US
N
1
N
N
N
2021-04-28
TEKLA LIFE SCIENCES INVESTORS
Laura Woodward
Laura Woodward
CCO