<SEC-DOCUMENT>0001104659-22-125155-index.html : 20221207
<SEC-HEADER>0001104659-22-125155.hdr.sgml : 20221207
<ACCEPTANCE-DATETIME>20221207151534
ACCESSION NUMBER:		0001104659-22-125155
CONFORMED SUBMISSION TYPE:	N-CSR
PUBLIC DOCUMENT COUNT:		14
CONFORMED PERIOD OF REPORT:	20220930
FILED AS OF DATE:		20221207
DATE AS OF CHANGE:		20221207
EFFECTIVENESS DATE:		20221207

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			TEKLA LIFE SCIENCES INVESTORS
		CENTRAL INDEX KEY:			0000884121
		IRS NUMBER:				043147016
		STATE OF INCORPORATION:			MA
		FISCAL YEAR END:			0930

	FILING VALUES:
		FORM TYPE:		N-CSR
		SEC ACT:		1940 Act
		SEC FILE NUMBER:	811-06565
		FILM NUMBER:		221450075

	BUSINESS ADDRESS:	
		STREET 1:		100 FEDERAL STREET
		STREET 2:		19TH FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02110
		BUSINESS PHONE:		6177728515

	MAIL ADDRESS:	
		STREET 1:		100 FEDERAL STREET
		STREET 2:		19TH FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02110

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	H&Q LIFE SCIENCES INVESTORS
		DATE OF NAME CHANGE:	19920929
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<TYPE>N-CSR
<SEQUENCE>1
<FILENAME>tm2225213d1_ncsr.htm
<DESCRIPTION>N-CSR
<TEXT>
Document 1 - file: tm2225213d1_ncsr.htm

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<DOCUMENT>
<TYPE>EX-99.CODE ETH
<SEQUENCE>2
<FILENAME>tm2225213d1_ex99-codeeth.htm
<DESCRIPTION>EXHIBIT 99.CODE ETH
<TEXT>
Document 2 - file: tm2225213d1_ex99-codeeth.htm

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<DOCUMENT>
<TYPE>EX-99.CERT
<SEQUENCE>3
<FILENAME>tm2225213d1_ex99-cert.htm
<DESCRIPTION>EXHIBIT 99.CERT
<TEXT>
Document 3 - file: tm2225213d1_ex99-cert.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.SECTION 19(A)
<SEQUENCE>4
<FILENAME>tm2225213d1_ex99-section19a.htm
<DESCRIPTION>EXHIBIT 99.SECTION 19(A)
<TEXT>
Document 4 - file: tm2225213d1_ex99-section19a.htm

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<DOCUMENT>
<TYPE>EX-99.906 CERT
<SEQUENCE>5
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<DESCRIPTION>EXHIBIT 99.906 CERT
<TEXT>
Document 5 - file: tm2225213d1_ex99-906cert.htm

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<DESCRIPTION>GRAPHIC
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Document 6 - file: j22252132_aa001.jpg

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Document 7 - file: j22252132_aa002.jpg

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Document 8 - file: j22252132_aa003.jpg

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Document 9 - file: j22252132_ba004.jpg

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<FILENAME>j22252132_ba005.jpg
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Document 10 - file: j22252132_ba005.jpg

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Document 11 - file: j22252132_ba006.jpg

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Document 12 - file: j22252132_ba007.jpg

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<TYPE>GRAPHIC
<SEQUENCE>13
<FILENAME>j22252132_ba008.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 13 - file: j22252132_ba008.jpg

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<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>14
<FILENAME>j22252132_ba009.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 14 - file: j22252132_ba009.jpg

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