<SEC-DOCUMENT>0001104659-22-068021-index.html : 20220603
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<ACCEPTANCE-DATETIME>20220603150143
ACCESSION NUMBER:		0001104659-22-068021
CONFORMED SUBMISSION TYPE:	N-CSRS
PUBLIC DOCUMENT COUNT:		14
CONFORMED PERIOD OF REPORT:	20220331
FILED AS OF DATE:		20220603
DATE AS OF CHANGE:		20220603
EFFECTIVENESS DATE:		20220603

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			TEKLA LIFE SCIENCES INVESTORS
		CENTRAL INDEX KEY:			0000884121
		IRS NUMBER:				043147016
		STATE OF INCORPORATION:			MA
		FISCAL YEAR END:			0930

	FILING VALUES:
		FORM TYPE:		N-CSRS
		SEC ACT:		1940 Act
		SEC FILE NUMBER:	811-06565
		FILM NUMBER:		22994033

	BUSINESS ADDRESS:	
		STREET 1:		100 FEDERAL STREET
		STREET 2:		19TH FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02110
		BUSINESS PHONE:		6177728515

	MAIL ADDRESS:	
		STREET 1:		100 FEDERAL STREET
		STREET 2:		19TH FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02110

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	H&Q LIFE SCIENCES INVESTORS
		DATE OF NAME CHANGE:	19920929
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<FILENAME>tm228076d1_ncsrs.htm
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Document 1 - file: tm228076d1_ncsrs.htm

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<TYPE>EX-99.CERT
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<FILENAME>tm228076d1_ex99cert.htm
<DESCRIPTION>EXHIBIT 99.CERT
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Document 2 - file: tm228076d1_ex99cert.htm

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<DOCUMENT>
<TYPE>EX-19.SECTION19(A)
<SEQUENCE>3
<FILENAME>tm228076d1_ex99section19a.htm
<DESCRIPTION>EXHIBIT 19.SECTION19(A)
<TEXT>
Document 3 - file: tm228076d1_ex99section19a.htm

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<DOCUMENT>
<TYPE>EX-99.906 CERT
<SEQUENCE>4
<FILENAME>tm228076d1_ex99-906cert.htm
<DESCRIPTION>EXHIBIT 99.906 CERT
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Document 4 - file: tm228076d1_ex99-906cert.htm

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Document 5 - file: j2280762_aa001.jpg

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Document 6 - file: j2280762_aa002.jpg

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Document 7 - file: j2280762_aa003.jpg

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Document 8 - file: j2280762_ba004.jpg

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Document 9 - file: j2280762_ba005.jpg

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Document 10 - file: j2280762_ba006.jpg

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Document 11 - file: j2280762_ba007.jpg

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Document 12 - file: j2280762_ba008.jpg

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Document 13 - file: j2280762_ba009.jpg

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Document 14 - file: j2280762_ba010.jpg

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