Exhibit 99.a(iii)

H&Q LIFE SCIENCES INVESTORS

CERTIFICATE OF AMENDMENT

The undersigned hereby certifies that he is a Trustee of H&Q Life Sciences Investors (the “Trust”), a Massachusetts business trust, and that pursuant to Sections 2.3 and 8.3 of a Declaration of Trust dated February 20, 1992, as amended by a written instrument executed by a majority of the Trustees, William R. Hambrecht has been appointed Trustee of the Trust to fill the vacancy left by the resignation of Roger F. Killion from such position.

Dated: August 11, 1995	/s/ Alan G. Carr
	Alan G. Carr, as a Trustee

COMMONWEALTH OF MASSACHUSETTS

Suffolk, ss.

On the 11^th day of August, 1995, then personally appeared before me Alan G. Carr who acknowledged the foregoing instrument to be his free act and deed.

/s/ Susan M. Hoyt

Notary Public

My Commission Expires: 10/12/95