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Property and Equipment:
9 Months Ended
Sep. 30, 2021
Property, Plant and Equipment [Abstract]  
Property and Equipment [Text Block] Property and Equipment
Property and equipment consisted of the following (in thousands): 
 September 30, 2021December 31, 2020
Machinery and equipment$310,651 $291,331 
Land, building and building improvements242,786 241,199 
Molds60,380 60,381 
Computer equipment and software99,781 98,311 
Furniture and fixtures7,686 7,767 
Instruments placed with customers(1)
96,499 90,383 
Construction in progress61,890 53,724 
Total property and equipment, cost879,673 843,096 
Accumulated depreciation(421,632)(376,468)
Property and equipment, net$458,041 $466,628 
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(1) Instruments placed with customers consist of drug-delivery and monitoring systems placed with customers under operating leases.

    Depreciation expense was $16.4 million and $49.1 million for the three and nine months ended September 30, 2021, respectively, as compared to $15.6 million and $46.7 million for the three and nine months ended September 30, 2020, respectively.