10-Q

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 10-Q

QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF

THE SECURITIES EXCHANGE ACT OF 1934

For the quarter ended: September 30, 2012

Commission File Number: 0-19871

STEMCELLS, INC.

(Exact name of registrant as specified in its charter)

DELAWARE	94-3078125
(State or other jurisdiction of incorporation or organization)	(I.R.S. Employer identification No)

7707 Gateway Blvd

Newark, CA 94560

(Address of principal executive offices including zip code)

(510) 456-4000

(Registrant’s telephone number, including area code)

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding twelve months (or for such shorter periods that the registrant was required to file such reports) and (2) has been subject to such filing requirements for the past 90 days.    Yes  x    No  ¨

Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T (§ 232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such files).    Yes  x    No  ¨

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See the definitions of “large accelerated filer,” “accelerated filer” and “smaller reporting company” in Rule 12b-2 of the Exchange Act. (Check one):

Large accelerated filer	¨	Accelerated filer	x
Non-accelerated filer	¨  (Do not check if a smaller reporting company)	Smaller reporting company	¨

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).    Yes  ¨    No  x

At October 26, 2012, there were 37,440,305 shares of Common Stock, $.01 par value, issued and outstanding.

STEMCELLS, INC.

INDEX

	Page Number
PART I. FINANCIAL INFORMATION		3
Item 1. Financial Statements (Unaudited)		3
Condensed Consolidated Balance Sheets at September 30, 2012 and December 31, 2011		3
Condensed Consolidated Statements of Operations for the three and nine months ended September  30, 2012 and 2011		4
Condensed Consolidated Statements of Comprehensive Income for the three and nine months ended September 30, 2012 and 2011		5
Condensed Consolidated Statements of Cash Flows for the nine months ended September 30, 2012 and 2011		6
Notes to Condensed Consolidated Financial Statements		7
Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations		22
Item 3. Quantitative and Qualitative Disclosures About Market Risk		35
Item 4. Controls and Procedures		36
PART II. OTHER INFORMATION		37
Item 1. Legal Proceedings		37
Item 1A. Risk Factors		37
Item 2. Unregistered Sales of Equity Securities and Use of Proceeds		37
Item 3. Defaults Upon Senior Securities		37
Item 4. Mine Safety Disclosures		37
Item 5. Other Information		37
Item 6. Exhibits		37
SIGNATURES		38

NOTE REGARDING REFERENCES TO US AND OUR COMMON STOCK

Throughout this Form 10-Q, the words “we,” “us,” “our,” and “StemCells” refer to StemCells, Inc., including our directly and indirectly wholly-owned subsidiaries. “Common stock” refers to the common stock, $.01 par value, of StemCells, Inc.

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PART I-FINANCIAL INFORMATION

ITEM 1. FINANCIAL STATEMENTS

STEMCELLS, INC.

CONDENSED CONSOLIDATED BALANCE SHEETS

(unaudited)

	September 30, 2012			December 31, 2011
ASSETS
Current assets:
Cash and cash equivalents	$	15,712,688		$	13,311,261
Marketable securities, current		6,031,735			3,280,591
Trade receivables		99,479			54,527
Other receivables		220,462			213,500
Prepaid assets		388,292			506,464
Other assets, current		791,454			22,063
Total current assets		23,244,110			17,388,406
Property, plant and equipment, net		1,535,590			2,054,563
Other assets, non-current		1,033,206			1,856,057
Goodwill		1,967,570			1,895,000
Other intangible assets, net		1,876,976			2,011,473
Total assets	$	29,657,452		$	25,205,499
LIABILITIES AND STOCKHOLDERS’ EQUITY
Current liabilities:
Accounts payable	$	960,501		$	1,066,495
Accrued expenses and other current liabilities		1,510,037			2,970,251
Accrued wind-down expenses, current		1,317,676			1,360,766
Deferred revenue, current		55,955			43,910
Capital lease obligation, current		6,765			17,979
Deferred rent, current		—			2,603
Bonds payable, current		202,500			191,250
Total current liabilities		4,053,434			5,653,254
Bonds payable, non-current		178,750			331,250
Capital lease obligations, non-current		14,415			—
Fair value of warrant liability		14,483,148			6,042,315
Deposits and other long-term liabilities		246,439			281,807
Accrued wind-down expenses, non-current		—			774,020
Deferred rent, non-current		1,373,767			1,301,167
Deferred revenue, non-current		83,942			96,562
Total liabilities		20,433,895			14,480,375
Commitments and contingencies (Note 7)
Stockholders’ equity:
Common stock, $0.01 par value; 75,000,000 shares authorized; issued and outstanding 35,018,336 at September 30, 2012 and 22,427,955 at December 31, 2011		1,598,679			1,472,776
Additional paid-in capital		365,787,830			341,811,657
Accumulated deficit		(358,332,729	)		(332,600,022	)
Accumulated other comprehensive income		169,777			40,713
Total stockholders’ equity		9,223,557			10,725,124
Total liabilities and stockholders’ equity	$	29,657,452		$	25,205,499

See Notes to Condensed Consolidated Financial Statements.

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STEMCELLS, INC.

CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS

(unaudited)

	Three months ended September 30,						Nine months ended September 30,
	2012			2011			2012			2011
Revenue:
Revenue from licensing agreements, grants and other	$	60,739		$	41,265		$	471,501		$	162,614
Revenue from product sales		203,256			182,321			685,364			516,536
Total revenue		263,995			223,586			1,156,865			679,150
Cost of product sales		71,891			60,501			208,127			167,390
Gross profit		192,104			163,085			948,738			511,760
Operating expenses:
Research and development		3,478,142			4,524,334			11,165,599			15,103,845
Selling, general and administrative		1,636,438			1,733,229			5,336,105			5,912,220
Wind-down expenses		154,742			68,694			199,799			258,749
Total operating expenses		5,269,322			6,326,257			16,701,503			21,274,814
Loss from operations		(5,077,218	)		(6,163,172	)		(15,752,765	)		(20,763,054	)
Other income (expense):
Change in fair value of warrant liability		(11,239,465	)		1,697,194			(9,974,685	)		6,500,377
Realized gain on sale of marketable securities		—			—			—			83,750
Interest income		2,372			3,514			9,393			11,332
Interest expense		(11,392	)		(16,585	)		(40,014	)		(56,585	)
Other income (expense), net		(11,087	)		144,697			25,364			107,400
Total other income (expense), net		(11,259,572	)		1,828,820			(9,979,942	)		6,646,274
Net loss	$	(16,336,790	)	$	(4,334,352	)	$	(25,732,707	)	$	(14,116,780	)
Basic and diluted net loss per share	$	(0.54	)	$	(0.31	)	$	(0.99	)	$	(1.02	)
Weighted average number of common shares outstanding, basic and diluted		30,168,475			14,009,341			25,992,764			13,831,749

See Notes to Condensed Consolidated Financial Statements.

4

STEMCELLS, INC.

CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME

(unaudited)

	Three months ended September 30,						Nine months ended September 30,
	2012			2011			2012			2011
Net loss	$	(16,336,790	)	$	(4,334,352	)	$	(25,732,707	)	$	(14,116,780	)
Other comprehensive income (loss)
Foreign currency translation adjustments		98,706			(133,593	)		125,854			66,441
Unrealized gains (losses) on marketable securities		587			(5,413	)		3,210			(123,905	)
Other comprehensive income (loss)		99,293			(139,006	)		129,064			(57,464	)
Comprehensive loss	$	(16,237,497	)	$	(4,473,358	)	$	(25,603,643	)	$	(14,174,244	)

See Notes to Condensed Consolidated Financial Statements.

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STEMCELLS, INC.

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS

(unaudited)

	Nine months ended September 30,
	2012			2011
Cash flows from operating activities:
Net loss	$	(25,732,707	)	$	(14,116,780	)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization		759,527			917,147
Stock-based compensation		2,227,145			2,636,445
Gain on sale of marketable securities		—			(83,750	)
Loss on disposal of fixed assets		—			32,145
Change in fair value of warrant liability		9,974,685			(6,500,377	)
Changes in operating assets and liabilities:
Other receivables		19,432			252
Trade receivables		(40,584	)		(281,709	)
Prepaid and other current assets		170,667			465,514
Other assets, non-current		32,926			18,830
Accounts payable and accrued expenses		(1,613,123	)		(142,120	)
Accrued wind-down expenses		(817,110	)		(820,708	)
Deferred revenue		(665	)		(4,541	)
Deferred rent		69,997			1,034,088
Net cash used in operating activities		(14,949,810	)		(16,845,564	)
Cash flows from investing activities:
Purchase of marketable securities		(8,109,933	)		(10,223,957	)
Proceeds from the sale and maturity of marketable securities		5,362,000			5,134,206
Purchases of property, plant and equipment		(19,729	)		(330,740	)
Proceeds from sale of property, plant and equipment		—			42,427
Net cash used in investing activities		(2,767,662	)		(5,378,064	)
Cash flows from financing activities:
Proceeds from issuance of common stock, net of issuance costs		16,196,587			10,426,121
Proceeds from the exercise of stock options		—			2,386
Proceeds from the exercise of warrants, net of issuance costs		4,153,584			—
Payments related to net share issuance of stock based awards		(59,090	)		(396,201	)
Repayment of capital lease obligations		(18,521	)		(50,246	)
Repayment of bonds payable		(141,250	)		(130,000	)
Net cash provided by financing activities		20,131,310			9,852,060
Increase (decrease) in cash and cash equivalents		2,413,838			(12,371,565	)
Effects of foreign exchange rate changes on cash		(12,411	)		(42,182	)
Cash and cash equivalents, beginning of period		13,311,261			19,707,821
Cash and cash equivalents, end of period	$	15,712,688		$	7,294,074
Supplemental disclosure of cash flow information:
Interest paid	$	40,114		$	56,585
Supplemental schedule of non-cash investing and financing activities:
Stock issued for an option agreement	$	50,000	1		—
Equipment acquired under a capital lease	$	21,721	2		—

See Notes to Condensed Consolidated Financial Statements.

¹  In September 2012, we issued 24,753 shares of restricted common stock under the terms of an agreement with a developer of biological materials in return for certain product rights including an exclusive right of first offer to commercialize the developer’s products as may be developed on or before April 18, 2017.

²  Represents the present value of future minimum capital lease payments for equipment leased in the third quarter of 2012.

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Notes to Condensed Consolidated Financial Statements (Unaudited)

September 30, 2012 and 2011

Note 1. Summary of Significant Accounting Policies

Nature of Business

StemCells, Inc., a Delaware corporation, is a biopharmaceutical company that operates in one segment, the research, development, and commercialization of stem cell therapeutics and related technologies.

The accompanying financial data as of September 30, 2012 and for the three and nine months ended September 30, 2012 and 2011 have been prepared by us, without audit, pursuant to the rules and regulations of the Securities and Exchange Commission (SEC). Certain information and footnote disclosures normally included in financial statements prepared in accordance with accounting principles generally accepted in the United States (U.S. GAAP) have been condensed or omitted pursuant to these rules and regulations. The December 31, 2011 condensed consolidated balance sheet was derived from audited financial statements, but does not include all disclosures required by U.S. GAAP. However, we believe that the disclosures are adequate to make the information presented not misleading. These condensed consolidated financial statements should be read in conjunction with the consolidated financial statements and the notes thereto included in our Annual Report on Form 10-K for the fiscal year ended December 31, 2011.

We have incurred significant operating losses since inception. We expect to incur additional operating losses over the foreseeable future. We have very limited liquidity and capital resources and must obtain significant additional capital and other resources in order to provide funding for our product development efforts, the acquisition of technologies, businesses and intellectual property rights, preclinical and clinical testing of our products, pursuit of regulatory approvals, acquisition of capital equipment, laboratory and office facilities, establishment of production capabilities, selling, general and administrative expenses and other working capital requirements. We rely on our cash reserves, proceeds from equity and debt offerings, proceeds from the transfer or sale of intellectual property rights, equipment, facilities or investments, government grants and funding from collaborative arrangements, to fund our operations. If we exhaust our cash reserves and are unable to obtain adequate financing, we may be unable to meet our operating obligations and we may be required to initiate bankruptcy proceedings. The financial statements do not include any adjustments to reflect the possible future effects on the recoverability and classification of assets or the amounts and classification of liabilities that may result from the outcome of this uncertainty.

Reverse Stock Split

We effected a 1-for-10 reverse stock split on July 6, 2011. As a result of the reverse stock split, the outstanding shares of common stock issued and outstanding were reduced from approximately 139 million to 13.9 million. Concurrent with the reverse stock split, we reduced the authorized number of common shares from 250 million to 75 million. The reverse stock split proportionately reduced all issued and outstanding shares of our common stock, as well as common stock underlying stock options, warrants and other common stock based equity grants outstanding immediately prior to the effectiveness of the reverse stock split. The exercise price on outstanding equity-based grants was proportionately increased, and the number of shares available under our equity-based plans was proportionately reduced. Share and per share data (except par value) for the periods presented reflect the effects of this reverse stock split. References to numbers of shares of common stock and per share data in the accompanying financial statements and notes thereto have been adjusted to reflect the reverse stock split on a retroactive basis.

Principles of Consolidation

The condensed consolidated financial statements include the accounts of StemCells, Inc., and our wholly-owned subsidiaries, including StemCells California, Inc., Stem Cell Sciences Holdings Ltd, and Stem Cell Sciences (UK) Ltd. All significant intercompany accounts and transactions have been eliminated.

Use of Estimates

The preparation of financial statements in conformity with U.S. GAAP requires management to make judgments, assumptions and estimates that affect the amounts reported in our condensed consolidated financial statements and accompanying notes. Actual results could differ materially from these estimates.

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Significant estimates include the following:

• the grant date fair value of stock-based awards recognized as compensation expense (see Note 5, “Stock-Based Compensation”);

• accrued wind-down expenses (see Note 6, “Wind-Down Expenses”);

• the fair value of warrants recorded as a liability (see Note 8, “Warrant Liability”); and

• the fair value of goodwill and other intangible assets (see Note 4, “Goodwill and Other Intangible Assets”).

Financial Instruments

Cash and Cash Equivalents

Cash equivalents are money market accounts, money market funds and investments with maturities of 90 days or less from the date of purchase.

Marketable Securities

Our existing marketable securities are designated as available-for-sale securities. These securities are carried at fair value (see Note 2, “Financial Instruments”), with the unrealized gains and losses reported as a component of stockholders’ equity. Management determines the appropriate designation of its investments (current or non-current) in marketable securities at the time of purchase and reevaluates such designation as of each balance sheet date. The cost of securities sold is based upon the specific identification method.

If the estimated fair value of a security is below its carrying value, we evaluate whether we have the intent and ability to retain our investment for a period of time sufficient to allow for any anticipated recovery to the cost of the investment, and whether evidence indicating that the cost of the investment is recoverable within a reasonable period of time outweighs evidence to the contrary. Other-than-temporary declines in estimated fair value of all marketable securities are charged to “Other income (expense), net” in the accompanying condensed consolidated statements of operations. No such impairment was recognized during the three and nine months ended September 30, 2012 or 2011.

Trade and Other Receivables

Our receivables generally consist of interest income on our financial instruments, revenue from licensing agreements and grants, revenue from product sales, and rent from our sub-lease tenants.

Warrant Liability

We account for our warrants in accordance with U.S. GAAP which defines how freestanding contracts that are indexed to and potentially settled in a company’s own stock should be measured and classified. Authoritative accounting guidance prescribes that only warrants issued by us under contracts that cannot be net-cash settled, and are both indexed to and settled in our common stock, can be classified as equity. As part of both our November 2008 and November 2009 financings, we issued warrants with five year terms to purchase 1,034,483 and 400,000 shares of our common stock at $23.00 and $15.00 per share, respectively. As part of our December 2011 financing, we issued Series A Warrants with a five year term to purchase 8,000,000 shares at $1.40 per share and Series B Warrants with a ninety trading day term to purchase 8,000,000 units at $1.25 per unit. Each unit underlying the Series B Warrants consisted of one share of our common stock and one Series A Warrant. In the first and second quarter of 2012, an aggregate of 2,700,000 Series B Warrants were exercised. For the exercise of these warrants, we issued 2,700,000 shares of our common stock and 2,700,000 Series A Warrants with an exercise price of $1.40 per share. The remaining 5,300,000 Series B Warrants expired unexercised by their terms on May 2, 2012. As terms of the warrants issued in 2008 and 2009, as well as the Series A and Series B warrants, do not meet the specific conditions for equity classification, we are required to classify the fair value of these warrants as a liability, with subsequent changes in fair value to be recorded as income (loss) due to change in fair value of warrant liability. The fair value of the warrants issued in the 2008 and 2009 financings is determined using the Black-Scholes-Merton (Black-Scholes) option pricing model and the fair value of the Series A and Series B Warrants is determined using a Monte Carlo simulation model (see Note 8, “Warrant Liability”). The fair value is affected by changes in inputs to these models including our stock price, expected stock price volatility, the contractual term, and the risk-free interest rate. The use of a Monte Carlo simulation model requires input of additional assumptions including the progress of our R&D programs and its affect on potential future financings. We will continue to classify the fair value of the warrants as a liability until the warrants are exercised, expire or are amended in a way that would no longer require these warrants to be classified as a liability.

8

Goodwill and Other Intangible Assets

Goodwill and intangible assets deemed to have indefinite lives are not amortized but are subject to annual impairment tests. If the assumptions and estimates used to allocate the purchase price are not correct, or if business conditions change, purchase price adjustments or future asset impairment charges could be required. We test goodwill for impairment on an annual basis or more frequently if we believe indicators of impairment exist. Impairment evaluations involve management estimates of asset useful lives and future cash flows. Significant management judgment is required in the forecasts of future operating results that are used in the evaluations, and it is possible, even likely, that the plans and estimates used may be incorrect. If our actual results, or the plans and estimates used in future impairment analysis are lower than the original estimates used to assess the recoverability of these assets, we could incur additional impairment charges in a future period. We completed our annual impairment testing during the fourth quarter of 2011, and determined that there was no impairment of goodwill.

Prior to fiscal year 2001, we capitalized certain patent costs, which are being amortized over the estimated life of the patent and would be expensed at the time such patents are deemed to have no continuing value. Since 2001, all patent costs are expensed as incurred. License costs are capitalized and amortized over the estimated life of the related license agreement.

Revenue Recognition

We currently recognize revenue resulting from the licensing and use of our technology and intellectual property, from government grants, from services provided to third parties, and from product sales. Licensing agreements may contain multiple elements, such as upfront fees, payments related to the achievement of particular milestones and royalties. Revenue from upfront fees for licensing agreements that contain multiple elements are generally deferred and recognized on a straight-line basis over the term of the agreement. Fees associated with substantive at risk performance-based milestones are recognized as revenue upon completion of the scientific or regulatory event specified in the agreement, and royalties received are recognized as earned. Revenue from licensing agreements is recognized net of a fixed percentage due to licensors as royalties. Grant revenue from government agencies are funds received to cover specific expenses and are recognized as earned upon either the incurring of reimbursable expenses directly related to the particular research plan or the completion of certain development milestones as defined within the terms of the relevant collaborative agreement or grant. Revenue from services to third parties is recognized when we have provided the agreed upon services. Revenue from product sales are recognized when the product is shipped and the order fulfilled.

Stock-Based Compensation

Compensation expense for stock-based payment awards to employees is based on their grant date fair value as calculated and amortized over their vesting period. See Note 5, “Stock-Based Compensation” for further information.

We use the Black-Scholes model to calculate the fair value of stock-based awards.

Per Share Data

Basic net income or loss per share is computed by dividing net income or loss by the weighted average number of shares of common stock outstanding during the period. Diluted net income or loss per share is computed based on the weighted average number of shares of common stock and other dilutive securities. To the extent these securities are anti-dilutive, they are excluded from the calculation of diluted earnings per share.

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The following is a reconciliation of the numerators and denominators of the basic and diluted net income or loss per share computations:

	Three months ended September 30,						Nine months ended September 30,
	2012			2011			2012			2011
Net loss	$	(16,336,790	)	$	(4,334,352	)	$	(25,732,707	)	$	(14,116,780	)
Weighted average shares outstanding used to compute basic and diluted net income or loss per share		30,168,475			14,009,341			25,992,764			13,831,749
Basic and diluted net loss per share	$	(0.54	)	$	(0.31	)	$	(0.99	)	$	(1.02	)

The following outstanding potentially dilutive common stock equivalents were excluded from the computation of diluted net income or loss per share because the effect would have been anti-dilutive as of September 30:

	2012		2011
Options		474,917		895,962
Restricted stock units		1,516,199		338,041
Warrants		10,689,083		1,434,483
Total		12,680,199		2,668,486

Comprehensive Income (Loss)

Comprehensive income (loss) is comprised of net income or loss and other comprehensive income or loss (OCL). OCL includes certain changes in stockholders’ equity that are excluded from net income or loss. Specifically, we include in OCL changes in unrealized gains and losses on our marketable securities and unrealized gains and losses on foreign currency translations. Accumulated other comprehensive income was $169,777, as of September 30, 2012, and $40,713, as of December 31, 2011.

Note 2. Financial Instruments

The following table summarizes the fair value of our cash, cash equivalents and available-for-sale marketable securities held in our current investment portfolio:

	Amortized Cost		Gross Unrealized Gains		Gross Unrealized (Losses)			Fair Value
September 30, 2012
Cash	$	281,065	$	—	$	—		$	281,065
Cash equivalents		15,431,623		—		—			15,431,623
Marketable debt securities, current		6,031,219		516		—			6,031,735
Total cash, cash equivalents, and marketable securities	$	21,743,907	$	516	$	—		$	21,744,423
December 31, 2011
Cash	$	291,093	$	—	$	—		$	291,093
Cash equivalents		13,020,168		—		—			13,020,168
Marketable debt securities, current		3,283,209		—		(2,618	)		3,280,591
Total cash, cash equivalents, and marketable securities	$	16,594,470	$	—	$	(2,618	)	$	16,591,852

Gross unrealized gains and losses on cash equivalents were not significant at September 30, 2012 and December 31, 2011. At September 30, 2012, our investment in money market accounts are composed primarily of U.S. Treasury debt securities, which are classified as cash equivalents in our Consolidated Balance Sheet due to their short maturities. Our investment in short-term marketable debt securities are composed primarily of commercial paper and corporate debt securities.

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Note 3. Fair Value Measurement

The following tables present our assets and liabilities that are measured at fair value on a recurring basis and are categorized using the fair value hierarchy. The fair value hierarchy has three levels based on the reliability of the inputs used to determine fair value.

Level 1 — Observable inputs that reflect quoted prices (unadjusted) for identical assets or liabilities in active markets.

Level 2 — Directly or indirectly observable inputs other than in Level 1, that include quoted prices for similar assets or liabilities in active markets or quoted prices for identical or similar assets or liabilities in markets that are not active.

Level 3 — Unobservable inputs which are supported by little or no market activity that reflects the reporting entity’s own assumptions about the assumptions that market participants would use in pricing the asset or liability.

The fair value hierarchy also requires us to maximize the use of observable inputs and minimize the use of unobservable inputs when measuring fair value.

Our cash equivalents are classified as Level 1 because they are valued primarily using quoted market prices.

Our bonds payable, marketable debt securities, and liability for warrants issued in our 2008 and 2009 financing, are classified as Level 2 as they are valued using alternative pricing sources and models utilizing market observable inputs.

Our liability for warrants issued in our 2011 financing is classified as Level 3 as the liability is valued using a Monte Carlo simulation model. Some of the significant inputs used to calculate the fair value of warrant liability include our stock price on the valuation date, expected volatility of our common stock as traded on NASDAQ, and risk-free interest rates that are derived from the yield on U.S. Treasury debt securities, all of which are observable from active markets. However, the use of a Monte Carlo simulation model requires the input of additional subjective assumptions including management’s assumptions regarding the likelihood of a re-pricing of these warrants pursuant to anti-dilution provisions and the progress of our R&D programs and its affect on potential future financings.

The following table presents financial assets and liabilities measured at fair value as of September 30, 2012:

	Fair Value Measurement at Report Date Using
	Quoted Prices in Active Markets for Identical Assets (Level 1)		Significant Other Observable Inputs (Level 2)		Unobservable Inputs (Level 3)		As of September 30, 2012
Financial assets:
Cash equivalents:
Money market funds	$	1,170,798	$	—	$	—	$	1,170,798
U.S. Treasury debt obligations		14,260,825		—		—		14,260,825
Marketable securities:
Debt securities		—		6,031,735		—		6,031,735
Total financial assets	$	15,431,623	$	6,031,735	$	—	$	21,463,358
Financial liabilities:
Bond obligation	$	—	$	381,250	$	—	$	381,250
Warrant liabilities		—		234,488		14,248,660		14,483,148
Total financial liabilities	$	—	$	615,738	$	14,248,660	$	14,864,398

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Level 2 Reconciliation

The following table presents a roll forward for financial assets and liabilities measured at fair value using significant other observable inputs (Level 2) for 2012.

	Level 2 Beginning Balance 12/31/11 $		Net transfers (to) from Level 1 $		Change included in earnings $		Settled $			Level 2 Ending Balance 09/30/12 $
Marketable debt securities		3,280,591		2,751,144		—		—			6,031,735
Bond obligation		522,500		—		—		(141,250	)		381,250
Warrant liabilities		31,195		—		203,293		—			234,488

Transfers from Level 2 to Level 1 are the net of, (i) maturities of short term marketable debt securities into cash and cash equivalents and (ii) additional purchases of marketable debt securities.

Level 3 Reconciliation

The following table presents a roll forward for liabilities measured at fair value using significant unobservable inputs (Level 3) for 2012.

	Warrant Liabilities
Balance at December 31, 2011	$	6,011,120
Less fair value of warrants exercised		(1,823,907	)
Less fair value of warrants expired		(3,560,063	)
Add fair value of warrants issued		1,714,436
Add change in fair value of warrants		11,907,074
Balance at September 30, 2012	$	14,248,660

Note 4. Goodwill and Other Intangible Assets

On April 1, 2009, we acquired the operations of Stem Cell Sciences Plc (SCS) for an aggregate purchase price of approximately $5,135,000. The acquired operations includes proprietary cell technologies relating to embryonic stem cells, induced pluripotent stem (iPS) cells, and tissue-derived (adult) stem cells; expertise and infrastructure for providing cell-based assays for drug discovery; a cell culture products business; and an intellectual property portfolio with claims relevant to cell processing, reprogramming and manipulation, as well as to gene targeting and insertion.

The purchase price was allocated as follows:

	Allocated purchase Price		Estimated life of intangible assets in years
Net tangible assets	$	36,000
Intangible assets:
Customer relationships and developed technology		1,310,000		6 to 9
In-process research and development		1,340,000		N/A
Trade name		310,000		15
Goodwill		2,139,000		N/A
Total	$	5,135,000

In-process research and development assets relate to: 1) the acquisition of certain intellectual property rights not expected to expire until 2027 related to our program focused on developing genetically engineered rat models of human disease (our “Transgenic Rat Program”); and 2) the acquisition of certain technology related to the commercialization of our SC Proven cell culture products and the development and commercialization of cell-based assay platforms for use in drug discovery and development (our “Assay Development Program”).

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At the time of valuation (April 2009), our Transgenic Rat Program was in its nascent stage and our Assay Development Program was expected to achieve proof of concept by 2012. Neither program was expected to begin generating revenue until 2011-2012. In December 2011, in part because of management’s decision to focus on our therapeutic product development programs and not to allocate time and resources to the assays technology, we determined that we could not predict the future cash flows from the intangible IPR&D asset related to the Assay Development Program. Therefore, at December 31, 2011, we determined that the intangible asset was impaired and wrote off the approximately $655,000 carrying value of the asset.

Trade name relates to the “SC Proven” trademark of our cell culture products which we expect to market for 15 years from the date of acquisition, based on which, we estimated a remaining useful life of 15 years from the valuation date.

The following table presents changes in goodwill:

Balance as of December 31, 2011	$	1,895,000
Foreign currency translation		72,570
Balance as of September 30, 2012	$	1,967,570

The components of our other intangible assets at September 30, 2012 are summarized below:

Other Intangible Asset Class	Cost		Impairment			Accumulated Amortization			Foreign Currency Translation		Net Carrying Amount
Customer relationships and developed technology	$	1,310,000	$	—		$	(647,222	)	$	146,820	$	809,598
In-process research and development		1,340,000		(654,961	)		(270,687	)		131,710		546,062
Trade name		310,000		—			(79,716	)		35,936		266,220
Patents		979,612		—			(724,516	)		—		255,096
Total other intangible assets	$	3,939,612	$	(654,961	)	$	(1,722,141	)	$	314,466	$	1,876,976

Amortization expense was approximately $66,000 in the third quarter of 2012.

The expected future annual amortization expense for each of the next five years based on current balances of our intangible assets is approximately as follows:

For the year ending December 31:
2013	$	267,000
2014	$	267,000
2015	$	266,000
2016	$	261,000
2017	$	238,000

Note 5. Stock-Based Compensation

We currently grant stock-based awards under two equity incentive plans. As of September 30, 2012, we had 642,266 shares authorized to be granted under the two plans. Under these plans we may grant various types of equity awards to our employees, directors and consultants, at prices determined by our Board of Directors, including incentive stock options, nonqualified stock options, stock appreciation rights, restricted stock, restricted stock units, and performance-based shares. Incentive stock options may only be granted to employees under these plans with a grant price not less than the fair market value of the stock on the date of grant. We also use these plans to grant shares to employees for the employer match of employee 401(k) plan contributions.

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Our stock-based compensation expense for the three and nine months ended September 30 was as follows:

	Three months ended September 30,						Nine months ended September 30,
	2012			2011			2012			2011
Research and development expense	$	314,393		$	343,845		$	966,570		$	1,304,846
Selling, general and administrative expense		452,760			320,539			1,260,574			1,308,265
Total employee stock-based compensation	$	767,153		$	664,384		$	2,227,144		$	2,613,111
Effect on basic and diluted net loss per share	$	(0.03	)	$	(0.05	)	$	(0.09	)	$	(0.19	)

As of September 30, 2012, we had approximately $2,835,000 of total unrecognized compensation expense related to unvested awards of stock options and restricted stock units granted under our various equity incentive plans that we expect to recognize over a weighted-average vesting period of 1.9 years.

Stock Options

Generally, stock options granted to employees have a maximum term of ten years, and vest over a four year period from the date of grant; 25% vest at the end of one year, and 75% vest monthly over the remaining three-year service period. We may grant options with different vesting terms from time to time. Upon employee termination of service, any unexercised vested option will be forfeited three months following termination or the expiration of the option, whichever is earlier. Unvested options are forfeited on termination.

A summary of our stock option activity for the three months ended September 30, 2012 is as follows:

	Number of options			Weighted-average exercise price ($) per share
Balance at June 30, 2012		854,958			20.26
Granted		—			—
Exercised		—			—
Cancelled		(380,041	)		21.93
Outstanding options at September 30, 2012		474,917			18.91

A summary of changes in unvested options for the three months ended September 30, 2012 is as follows:

	Number of options			Weighted-average exercise price ($) per share		Weighted-average grant date fair value ($) per option
Unvested options at June 30, 2012		103,993			11.54		9.28
Granted		—			—		—
Vested		(14,466	)		12.04		9.71
Cancelled		(11,778	)		14.29		11.83
Unvested options at September 30, 2012		77,749			11.04		8.82

The estimated fair value of options vested was approximately $140,000 in the three months ended September 30, 2012.

Restricted Stock Units

We have granted restricted stock units (RSUs) to certain employees and members of the Board of Directors which entitle the holders to receive shares of our common stock upon vesting of the RSUs. The fair value of restricted stock units granted is based upon the market price of the underlying common stock as if it were vested and issued on the date of grant.

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A summary of changes in unvested restricted stock units for the three months ended September 30, 2012 is as follows:

	Number of RSUs			Weighted-average grant date fair value ($) per RSU
Unvested restricted stock units at June 30, 2012		1,467,533			2.12
Granted(1)		52,000			2.15
Vested		(3,333	)		12.59
Cancelled		—			—
Balance unvested at September 30, 2012		1,516,200			2.10

(1) 20,000 of these restricted stock units vest and convert into shares of our common stock after one year from the date of grant. 32,000 of these restricted stock units will vest and convert into shares of our common stock over a four year period from the date of grant; one-fourth of the award will vest on each grant date anniversary following the grant.

Stock Appreciation Rights

In July 2006, we granted cash-settled Stock Appreciation Rights (SARs) to certain employees that give the holder the right, upon exercise, to the difference between the price per share of our common stock at the time of exercise and the exercise price of the SARs.

The SARs have a maximum term of ten years with an exercise price of $20.00, which is equal to the market price of our common stock at the date of grant. The SARs vest 25% on the first anniversary of the grant date and 75% vest monthly over the remaining three-year service period. All of the outstanding SARs as of September 30, 2012 are fully vested. Compensation expense is based on the fair value of SARs which is calculated using the Black-Scholes option pricing model.

The stock-based compensation expense and liability are re-measured at each reporting date through the earlier of date of settlement or forfeiture of the SARs.

A summary of the changes in SARs for the three months ended September 30, 2012 is as follows:

	Number of SARs
Outstanding at June 30, 2012		115,187
Granted		—
Exercised		—
Forfeited and expired		(4,594	)
Outstanding SARs at September 30, 2012		110,593
SARs exercisable at September 30, 2012		110,593

For the three months ended September 30, 2012 and 2011, the re-measured liability and expense for the respective periods related to the SARs were not significant.

The compensation expense related to the SARs recognized for the three months ended September 30, 2012 may not be representative of compensation expense for future periods and its resulting effect on net loss and net loss per share attributable to common stockholders, due to changes in the fair value calculation which is dependent on the stock price, volatility, interest and forfeiture rates, additional grants and subsequent periods of vesting. We will continue to recognize compensation cost each period, which will be the change in fair value from the previous period through the earlier date of settlement or forfeiture of the SARs.

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Note 6. Wind-Down Expenses

Rhode Island

In October 1999, we relocated to California from Rhode Island and established a wind down reserve for the estimated lease payments and operating costs of our scientific and administrative facility in Rhode Island. Even though we intend to dispose of the facility at the earliest possible time, we cannot determine with certainty a fixed date by which such disposal will occur. In light of this uncertainty, we periodically re-evaluate and adjust the reserve. We consider various factors such as our lease payments through to the end of the lease, operating expenses, the current real estate market in Rhode Island, and estimated subtenant income based on actual and projected occupancy.

The summary of the changes to our wind-down reserve related to this facility for 2012 and 2011 were as follows:

	January 1 to March 31, 2012			April 1 to June 30, 2012			July 1 to September 30, 2012			January 1 to September 30, 2012			January 1 to December 31, 2011
Accrued wind-down reserve at beginning of period	$	1,683,000		$	1,418,000		$	1,148,000		$	1,683,000		$	2,644,000
Less actual expenses recorded against estimated reserve during the period		(300,000	)		(280,000	)		(284,000	)		(864,000	)		(1,248,000	)
Additional expense recorded to revise estimated reserve at period-end		35,000			10,000			155,000			200,000			287,000
Revised reserve at period-end		1,418,000			1,148,000			1,019,000			1,019,000			1,683,000
Add deferred rent at period-end		401,000			350,000			299,000			299,000			452,000
Total accrued wind-down expenses at period-end (current and non-current)	$	1,819,000		$	1,498,000		$	1,318,000		$	1,318,000		$	2,135,000
Accrued wind-down expenses, current	$	1,428,000		$	1,498,000		$	1,318,000		$	1,318,000		$	1,361,000
Accrued wind-down expenses, non-current		391,000			—			—			—			774,000
Total accrued wind-down expenses	$	1,819,000		$	1,498,000		$	1,318,000		$	1,318,000		$	2,135,000

Note 7. Commitments and Contingencies

Leases

Capital Leases

We entered into direct financing transactions with the State of Rhode Island and received proceeds from the issuance of industrial revenue bonds totaling $5,000,000 to finance the construction of our pilot manufacturing facility in Rhode Island. The related lease agreements are structured such that lease payments fully fund all semiannual interest payments and annual principal payments through maturity in August 2014. The interest rate for the remaining bond series is 9.5%. The bond contains certain restrictive covenants which limit, among other things, the payment of cash dividends and the sale of the related assets. The outstanding principal was approximately $381,000 at September 30, 2012 and $523,000 at December 31, 2011.

Operating Leases

We lease various real properties under operating leases that generally require us to pay taxes, insurance, maintenance, and minimum lease payments. Some of our leases have options to renew.

Operating Leases — California

In September 2010, we entered into a two-year sublease agreement with Caliper Life Sciences, Inc., for approximately 13,200 square feet in a facility located in Mountain View, California. In June 2012, the sublease term was extended to September 30, 2013. We will pay approximately $1,081,000 in aggregate as rent over the term of the lease.

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In December 2010, we entered into a commercial lease agreement with BMR-Gateway Boulevard LLC (“BMR”), as landlord, for approximately 43,000 square feet of office and research space at BMR’s Pacific Research Center in Newark, California. The initial term of the lease is approximately eleven and one-half years, and we relocated our corporate headquarters and core research activities from a facility located at the Stanford Research Park in Palo Alto, California, to this facility in July 2011. The lease for the Palo Alto facility expired on August 31, 2011. We will pay approximately $17,869,000 in aggregate as rent over the term of the lease, which we recognize as operating lease expense on a straight-line basis. Deferred rent was approximately $1,374,000 as of September 30, 2012, and approximately $1,301,000 as of December 31, 2011. We constructed laboratories, offices and related infrastructure within the leased space during the first several months of the lease. As part of the lease, BMR has agreed to provide various financial allowances so that we can build initial and future laboratories, offices and other improvements, subject to customary terms and conditions relating to landlord-funded tenant improvements. As part of the lease, we have, until January 2013, an option to lease up to an additional 30,000 square feet in the building.

Operating Leases — Rhode Island

We entered into a fifteen-year lease agreement for a scientific and administrative facility (SAF) in Rhode Island in connection with a sale and leaseback arrangement in 1997. The lease term expires June 30, 2013 and includes escalating rent payments which we recognize on a straight-line basis. Deferred rent expense for this facility was approximately $299,000 at September 30, 2012 and $452,000 at December 31, 2011, and is included as part of the wind-down accrual on the accompanying condensed consolidated balance sheets. For the year 2012, we expect to pay approximately $1,172,000 in operating lease payments and estimated operating expenses of approximately $690,000, before receipt of sub-tenant income and we expect to receive, in aggregate, approximately $412,000 in sub-tenant rent and operating expenses. As a result of the above transactions, our estimated cash outlay net of sub-tenant rent for the SAF will be approximately $1,450,000 for 2012.

Operating Leases — United Kingdom

In January 2011, we amended the existing lease agreements of our wholly-owned subsidiary, Stem Cell Sciences (U.K.) Ltd, effectively reducing our leased space from approximately 5,000 square feet to approximately 1,900 square feet of office and lab space. The lease by its terms was extended to September 30, 2013. We expect to pay approximately 61,000 GBP as rental payments for 2012. StemCells, Inc. is the guarantor of Stem Cell Sciences (U.K.) Ltd’s obligations under the existing lease.

With the exception of the operating leases discussed above, we have not entered into any significant off balance sheet financial arrangements and have not established any special purpose entities. We have not guaranteed any debts or commitments of other entities or entered into any options on non-financial assets.

Contingencies

In July 2006, we filed suit against Neuralstem, Inc. in the Federal District Court for the District of Maryland, alleging that Neuralstem’s activities violate claims in four of the patents we exclusively licensed from NeuroSpheres, specifically U.S. Patent No. 6,294,346 (claiming the use of human neural stem cells for drug screening), U.S. Patent No. 7,101,709 (claiming the use of human neural stem cells for screening biological agents), U.S. Patent No. 5,851,832 (claiming methods for proliferating human neural stem cells), and U.S. Patent No. 6,497,872 (claiming methods for transplanting human neural stem cells). In May 2008, we filed a second patent infringement suit against Neuralstem and its two founders, Karl Johe and Richard Garr. In this suit, which we filed in the Federal District Court for the Northern District of California, we allege that Neuralstem’s activities infringe claims in two patents we exclusively license from NeuroSpheres, specifically U.S. Patent No. 7,361,505 (claiming composition of matter of human neural stem cells derived from any source material) and U.S. Patent No. 7,115,418 (claiming methods for proliferating human neural stem cells). In addition, we allege various state law causes of action against Neuralstem arising out of its repeated derogatory statements to the public about our patent portfolio. Also in May 2008, Neuralstem filed suit against us and NeuroSpheres in the Federal District Court for the District of Maryland seeking a declaratory judgment that the ‘505 and ‘418 patents are either invalid or are not infringed by Neuralstem and that Neuralstem has not violated California state law. In August 2008, the California court transferred our lawsuit against Neuralstem to Maryland for resolution on the merits. In July 2009, the Maryland District Court granted our motion to consolidate these two cases with the litigation we initiated against Neuralstem in 2006. Discovery is ongoing in these cases and we anticipate a trial date in 2013.

In addition to the actions described above, in April 2008, we filed an opposition to Neuralstem’s European Patent No. 0 915 968 (methods of isolating, propagating and differentiating CNS stem cells), because the claimed invention is believed by

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us to be unpatentable over prior art, including the patents exclusively licensed by us from NeuroSpheres. In December 2010, the European Patent Office ruled that all composition claims in Neuralstem’s ‘968 European patent were invalid and unpatentable over prior art including several of the NeuroSpheres patents licensed to us. Neuralstem has appealed this decision.

Effective 2008, as part of an indemnification agreement with NeuroSpheres, we are entitled to offset all litigation costs incurred in this patent infringement suit, against amounts that would otherwise be owed to NeuroSpheres under our exclusive license agreements with NeuroSpheres, such as annual maintenance fees, milestones and royalty payments. Under the terms of our license agreements, we are required to make annual payments of $50,000 to NeuroSpheres, and we expect to make these annual payments through the remaining life of the patent which, at December 31, 2010, was approximately 14 years. We have therefore capitalized $700,000 (14 years at $50,000 per year) to offset litigation costs. The amount capitalized is not dependent on the achievement of any milestones or related to any other contingent payments which may become due under the arrangement. We will reduce this asset by $50,000 per year in lieu of the cash payments due to NeuroSpheres. As the $50,000 annual payments are fully creditable against royalties due to NeuroSpheres, we have classified the capitalized amount as prepaid royalties under “Other assets, non-current” on our accompanying Consolidated Balance Sheets. We have concluded that the estimated balance of $650,000, as of September 30, 2012, is a fair estimate and realizable against future milestone and royalty payments to NeuroSpheres, and that litigation costs incurred above this amount will be expensed as incurred. Management will reevaluate this estimate on a quarterly basis based on actual costs and other relevant factors.

Note 8. Warrant Liability

We use various option pricing models, such as the Black-Scholes option pricing model and a Monte Carlo simulation model, to estimate fair value of warrants issued. In using these models, we make certain assumptions about risk-free interest rates, dividend yields, volatility, expected term of the warrants and other assumptions. Risk-free interest rates are derived from the yield on U.S. Treasury debt securities. Dividend yields are based on our historical dividend payments, which have been zero to date. Volatility is estimated from the historical volatility of our common stock as traded on NASDAQ. The expected term of the warrants is based on the time to expiration of the warrants from the date of measurement.

In November 2008, we sold 1,379,310 units to institutional investors at a price of $14.50 per unit, for gross proceeds of $20,000,000. The units, each of which consisted of one share of common stock and a warrant to purchase 0.75 shares of common stock at an exercise price of $23.00 per share, were offered as a registered direct offering under a shelf registration statement previously filed with, and declared effective by, the SEC. We received total proceeds, net of offering expenses and placement agency fees, of approximately $18,637,000. We recorded the fair value of the warrants to purchase 1,034,483 shares of our common stock as a liability. The fair value of the warrant liability is revalued at the end of each reporting period, with the change in fair value of the warrant liability recorded as a gain or loss in our condensed consolidated statements of operations. The fair value of the warrants will continue to be classified as a liability until such time as the warrants are exercised, expire or an amendment of the warrant agreement renders these warrants to be no longer classified as a liability.

The assumptions used for the Black-Scholes option pricing model are as follows:

	To Calculate Fair Value of Warrant Liability at
	September 30, 2012			December 31, 2011
Expected life (years)		1.6			2.4
Risk-free interest rate		0.2	%		0.3	%
Expected volatility		108.1	%		74.1	%
Expected dividend yield		0	%		0	%

	At September 30, 2012		At December 31, 2011		Change in Fair Value of Warrant Liability
Fair value of liability for warrants issued in 2008	$	129,785	$	2,224	$	127,561

In November 2009, we sold 1,000,000 units to institutional investors at a price of $12.50 per unit, for gross proceeds of $12,500,000. The units, each of which consisted of one share of common stock and a warrant to purchase 0.40 shares of common stock at an exercise price of $15.00 per share, were offered as a registered direct offering under a shelf registration statement previously filed with, and declared effective by, the SEC. We received total proceeds, net of offering expenses and placement agency fees, of approximately $11,985,000. We recorded the fair value of the warrants to purchase 400,000 shares

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of our common stock as a liability. The fair value of the warrant liability is revalued at the end of each reporting period, with the change in fair value of the warrant liability recorded as a gain or loss in our condensed consolidated statements of operations. The fair value of the warrants will continue to be classified as a liability until such time as the warrants are exercised, expire or an amendment of the warrant agreement renders these warrants to be no longer classified as a liability.

The assumptions used for the Black-Scholes option pricing model are as follows:

	To Calculate Fair Value of Warrant Liability at
	September 30, 2012			December 31, 2011
Expected life (years)		2.6			3.3
Risk-free interest rate		0.3	%		0.5	%
Expected volatility		90.1	%		90.8	%
Expected dividend yield		0	%		0	%

	At September 30, 2012		At December 31, 2011		Change in Fair Value of Warrant Liability
Fair value of liability for warrants issued in 2009	$	104,703	$	28,971	$	75,732

In December 2011, we raised gross proceeds of $10,000,000 through a public offering of 8,000,000 units and 8,000,000 Series B Warrants. The combination of units and Series B Warrants were sold at a public offering price of $1.25 per unit. Each Series B Warrant gave the holder the right to purchase one unit at an exercise price of $1.25 per unit and was exercisable until May 2, 2012, the 90th trading day after the date of issuance. Each unit consists of one share of our common stock and one Series A Warrant. Each Series A Warrant gives the holder the right to purchase one share of our common stock at an initial exercise price of $1.40 per share. The Series A Warrants are immediately exercisable upon issuance and will expire on the fifth anniversary of the closing date of the initial financing transaction in December 2011. The shares were offered under our shelf registration statement previously filed with previously filed with, and declared effective by, the SEC.

In the first and second quarter of 2012, an aggregate of 2,700,000 Series B Warrants were exercised. For the exercise of these warrants, we issued 2,700,000 shares of our common stock and 2,700,000 Series A Warrants with an initial exercise price of $1.40 per share and received gross proceeds of $3,375,000. The remaining 5,300,000 Series B Warrants expired unexercised by their terms on May 2, 2012.

In the third quarter of 2012, an aggregate of 1,445,400 Series A Warrants were exercised. For the exercise of these warrants, we issued 1,445,400 shares of our common stock and received gross proceeds of $977,900 and $1,045,660 in the third and fourth quarter of 2012 respectively.

The assumptions used for the Monte Carlo simulation model to value the Series A Warrants at September 30, 2012 are as follows:

Risk-free interest rate per year	0.5	%
Expected volatility per year	95.3	%
Expected dividend yield	0	%
Expected life in years	4.2

The use of a Monte Carlo simulation model requires the input of additional subjective assumptions including the progress of our R&D programs and its affect on potential future financings.

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The following table is a summary of the changes in fair value of warrant liability for the Series A Warrants for the three-month period ended September 30, 2012:

	Series A
	Number of Warrants			Fair value $
Balance at June 30, 2012		10,700,000		$	5,390,018
Less exercised		(1,445,400	)		(728,106	)
Changes in fair value		—			9,586,748
Balance at September 30, 2012		9,254,600		$	14,248,660

The following table is a summary of our outstanding warrants and fair value of our warrant liability as of September 30, 2012:

Warrants	Number Outstanding		Exercise Price ($) per share		Fair value
Warrants issued in 2008		1,034,483		23.00	$	129,785
Warrants issued in 2009		400,000		15.00		104,703
Series A Warrants		9,254,660		1.40		14,248,660
Total		10,689,143			$	14,483,148

The fair value of the warrant liability is revalued at the end of each reporting period, with the change in fair value of the warrant liability recorded as a gain or loss in our condensed consolidated statements of operations. The fair value of the warrants will continue to be classified as a liability until such time as the warrants are exercised, expire or an amendment of the warrant agreement renders these warrants to be no longer classified as a liability.

Note 9. Common Stock

In the third quarter of 2012, we sold a total of 7,956,061 shares of our common stock at an average price per share of $2.10 for gross proceeds of approximately $16,738,000. The shares were sold under a sales agreement entered into in June 2009 and the sales agent is paid compensation equal to 3% of gross proceeds pursuant to the terms of the agreement. The shares were offered under our shelf registration statement previously filed with, and declared effective by, the SEC.

In the first and second quarters of 2012, an aggregate of 2,700,000 Series B Warrants were exercised and we received gross proceeds of $3,375,000. The remaining 5,300,000 Series B Warrants expired unexercised by their terms on May 2, 2012. For the exercise of these warrants, we issued 2,700,000 shares of our common stock and 2,700,000 Series A Warrants. The Series A Warrants have an initial exercise price of $1.40 per share and will expire on the fifth anniversary of the closing date of the initial financing transaction in December 2011.

In the third quarter of 2012, an aggregate of 1,445,400 Series A Warrants were exercised. For the exercise of these warrants, we issued 1,445,400 shares of our common stock and received gross proceeds of $977,900 and $1,045,660 in the third and fourth quarters of 2012 respectively.

Note 10. California Institute for Regenerative Medicine Funding Program

In July 2012, the California Institute for Regenerative Medicine (CIRM) approved an award to us for up to $20 million under CIRM’s Disease Team Therapy Development Award program (RFA 10-05). The award is to fund preclinical development of our HuCNS-SC cells in cervical spinal cord injury over a maximum four-year period, with the goal of filing an investigational new drug application (IND) in that time.

In September 2012, CIRM approved a second award to us for up to $20 million under RFA 10-05. The award is to fund preclinical development of our proprietary HuCNS-SC cells in Alzheimer’s disease over a maximum four-year period, with the goal of filing an IND in that time.

Funding to for-profit companies under RFA 10-05 is expected to be structured as forgivable loans, in accordance with mutually agreed upon terms and conditions and CIRM regulations. As of September 30, 2012, we and CIRM were in discussions regarding the terms and conditions of the funding, and no funds had yet been disbursed to us from CIRM.

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Note 11. Subsequent Events

Subsequent to the end of the third quarter, 688,171 Series A Warrants were exercised at an exercise price of $1.40 per share. We will receive gross proceeds of approximately $963,000 and issue 688,171 shares of our common stock.

In October 2012, we sold a total of 1,691,410 shares of our common stock at an average price per share of $2.20 for gross proceeds of approximately $3,714,000. The shares were sold under a sales agreement entered into in June 2009 and the sales agent is paid compensation equal to 3% of gross proceeds pursuant to the terms of the agreement. The shares were offered under our shelf registration statement previously filed with, and declared effective by, the SEC.

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ITEM 2. MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS

This report contains forward looking statements within the meaning of Section 27A of the Securities Act and Section 21E of the Securities Exchange Act that involve substantial risks and uncertainties. Such statements include, without limitation, all statements as to expectation or belief and statements as to our future results of operations; the progress of our research, product development and clinical programs; the need for, and timing of, additional capital and capital expenditures; partnering prospects; costs of manufacture of products; the protection of, and the need for, additional intellectual property rights; effects of regulations; the need for additional facilities; and potential market opportunities. Our actual results may vary materially from those contained in such forward-looking statements because of risks to which we are subject, including the fact that additional trials will be required to confirm the safety and demonstrate the efficacy of our HuCNS-SC cells for the treatment of any disease or disorder; uncertainty as to whether the U.S. Food and Drug Administration (FDA), Swissmedic, or other regulatory authorities will permit us to proceed with clinical testing of proposed products despite the novel and unproven nature of our technologies; the risk that our clinical trials or studies could be substantially delayed beyond their expected dates or cause us to incur substantial unanticipated costs; uncertainties in our ability to obtain the capital resources needed to continue our current research and development operations and to conduct the research, preclinical development and clinical trials necessary for regulatory approvals; the uncertainty regarding our ability to obtain a corporate partner or partners, if needed, to support the development and commercialization of our potential cell-based therapeutics products; the uncertainty regarding the outcome of our clinical trials or studies we may conduct in the future; the uncertainty regarding the validity and enforceability of our issued patents; the risk that we may not be able to manufacture additional master and working cell banks when needed; the uncertainty whether any products that may be generated in our cell-based therapeutics programs will prove clinically safe and effective; the uncertainty whether we will achieve significant revenue from product sales or become profitable; uncertainties regarding our obligations with respect to our former facilities in Rhode Island; obsolescence of our technologies; competition from third parties; intellectual property rights of third parties; litigation risks; and other risks to which we are subject. All forward-looking statements attributable to us or to persons acting on our behalf are expressly qualified in their entirety by the cautionary statements and risk factors set forth in “Risk Factors” in Part I, Item 1A of our Form 10-K for the year ended December 31, 2011.

Overview

The Company

We are engaged in researching, developing, and commercializing stem cell therapeutics and enabling tools and technologies for stem cell-based research and drug discovery and development. Our research and development (R&D) programs are primarily focused on identifying and developing potential cell-based therapeutics which can either restore or support organ function. In particular, since we relocated our corporate headquarters to California in 1999, our R&D efforts have been directed at refining our methods for identifying, isolating, culturing, and purifying the human neural stem cell and developing this cell as potential cell-based therapeutics for the central nervous system (CNS). In our CNS Program, our HuCNS-SC^® product candidate (purified human neural stem cells) is currently in clinical development for several indications—Pelizeaus-Merzbacher Disease (PMD), which is a myelination disorder in the brain, chronic spinal cord injury and dry age-related macular degeneration (AMD). In February 2012, we completed a four-patient Phase I clinical trial in PMD. Results from this trial showed preliminary evidence of durable and progressive donor-derived myelination in all four patients. In addition, there were measurable gains in neurological function in three of the four patients, with the fourth patient clinically stable. The trial results were published in October 2012 in Science Translational Medicine, a peer review scientific journal. We are conducting a Phase I/II clinical trial for the treatment of chronic spinal cord injury. This trial is being

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conducted in Switzerland under authorization from Swissmedic, and represents the first time that neural stem cells have been transplanted as a potential therapeutic agent for spinal cord injury. We completed the enrollment and dosing of the first patient cohort, all of whom had complete spinal cord injuries, in December 2011, and in September 2012, presented interim six-month data from this cohort. The data continues to demonstrate a favorable safety profile, and shows considerable gains in sensory function in two of the three patients compared to pre-transplant baselines; the third patient remains stable. Also, in September 2012, the first patient with an incomplete spinal cord injury was enrolled and dosed with our proprietary HuCNS-SC cells. In June 2012, we initiated a Phase I/II clinical trial in dry AMD, and in October 2012, the first patient in this trial was enrolled and dosed. We previously completed a Phase I clinical trial in infantile and late infantile neuronal ceroid lipofuscinosis (NCL), and the data from that trial showed that our HuCNS-SC cells were well tolerated and non-tumorigenic, and that there was evidence of engraftment and long-term survival of the transplanted HuCNS-SC cells. In the second quarter of 2012, the California Institute for Regenerative Medicine (CIRM) approved two awards to us for up to $20 million each over a maximum four-year period to fund preclinical development of our HuCNS-SC cells for cervical spinal cord injury and for Alzheimer’s disease, with the goal of filing an investigational new drug application for each indication in that time. Funding from the awards are expected to be in the form of forgivable loans, the terms and conditions of which must be mutually agreed by CIRM and us. In October 2011, we formed a wholly-owned subsidiary to focus on both the therapeutic and research tool applications of our human liver engrafting cells (hLEC) technologies and to serve as an investment vehicle for those interested in a “pure play” liver cell company. For a brief description of our significant therapeutic research and development programs see Overview “Research and Development Programs” in the Business Section of Part I, Item 1 of our Form 10-K for the year ended December 31, 2011.

We are also engaged in developing and commercializing applications of our technologies to enable research, which we believe represent current and nearer-term commercial opportunities. Our portfolio of technologies includes cell technologies relating to embryonic stem cells, induced pluripotent stem (iPS) cells, and tissue-derived (adult) stem cells; expertise and infrastructure for providing cell-based assays for drug discovery; a cell culture products and antibody reagents business; and an intellectual property portfolio with claims relevant to cell processing, reprogramming and manipulation, as well as to gene targeting and insertion. Many of these enabling technologies were acquired in April 2009 as part of our acquisition of the operations of Stem Cell Sciences Plc (SCS).

We have not derived any revenue or cash flows from the sale or commercialization of any products except for license revenue for certain of our patented technologies and sales of cell culture products for use in research. As a result, we have incurred annual operating losses since inception and expect to incur substantial operating losses in the future. Therefore, we are dependent upon external financing from equity and debt offerings and revenue from collaborative research arrangements with corporate sponsors to finance our operations. We have no such collaborative research arrangements at this time and there can be no assurance that such financing or partnering revenue will be available when needed or on terms acceptable to us.

Before we can derive revenue or cash inflows from the commercialization of any of our therapeutic product candidates, we will need to: (i) conduct substantial in vitro testing and characterization of our proprietary cell types, (ii) undertake preclinical and clinical testing for specific disease indications; (iii) develop, validate and scale-up manufacturing processes to produce these cell-based therapeutics, and (iv) obtain required regulatory approvals. These steps are risky, expensive and time consuming.

Overall, we expect our R&D expenses to be substantial and to increase for the foreseeable future as we continue the development and clinical investigation of our current and future product candidates. However, expenditures on R&D programs are subject to many uncertainties, including whether we develop our product candidates with a partner or independently. We cannot forecast with any degree of certainty which of our current product candidates will be subject to future collaboration, when such collaboration agreements will be secured, if at all, and to what degree such arrangements would affect our development plans and capital requirements. In addition, there are numerous factors associated with the successful commercialization of any of our cell-based therapeutics, including future trial design and regulatory requirements, many of which cannot be determined with accuracy at this time given the stage of our development and the novel nature of stem cell technologies. The regulatory pathways, both in the United States and internationally, are complex and fluid given the novel and, in general, clinically unproven nature of stem cell technologies. At this time, due to such uncertainties and inherent risks, we cannot estimate in a meaningful way the duration of, or the costs to complete, our R&D programs or whether, when or to what extent we will generate revenues or cash inflows from the commercialization and sale of any of our therapeutic product candidates. While we are currently focused on advancing each of our product development programs, our future R&D expenses will depend on the determinations we make as to the scientific and clinical prospects of each product candidate, as well as our ongoing assessment of the regulatory requirements and each product candidate’s commercial potential.

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Given the early stage of development of our therapeutic product candidates, any estimates of when we may be able to commercialize one or more of these products would not be meaningful. Moreover, any estimate of the time and investment required to develop potential products based upon our proprietary HuCNS-SC and hLEC technologies will change depending on the ultimate approach or approaches we take to pursue them, the results of preclinical and clinical studies, and the content and timing of decisions made by the FDA, Swissmedic and other regulatory authorities. There can be no assurance that we will be able to develop any product successfully, or that we will be able to recover our development costs, whether upon commercialization of a developed product or otherwise. We cannot provide assurance that any of these programs will result in products that can be marketed or marketed profitably. If certain of our development-stage programs do not result in commercially viable products, our results of operations could be materially adversely affected.

The research markets served by our tools and technologies products are highly competitive, complex and dynamic. Technological advances and scientific discoveries have accelerated the pace of change in biological research, and stem cell technologies have been evolving particularly fast. We compete mainly by focusing on specialty media and antibody reagent products and cell-based assays, which are custom designed for use in stem cell-based research, where we believe our expertise, intellectual property and reputation give us competitive advantage. We believe that, in this particular market niche, our products and technologies offer customers specific advantages over those offered by our competitors. We compete by offering innovative, quality-controlled products, consistently made and designed to produce reproducible results. We continue to make investments in research and development, quality management, quality improvement, and product innovation. We cannot assure you that we will have sufficient resources to continue to make such investments. For the three month period ended September 30, 2012, we generated revenues from the sale of specialty cell culture products of approximately $203,000. We can give no assurances that we will be able to continue to generate such revenues in the future.

Significant Events

In July 2012, we presented preclinical data demonstrating that our proprietary human neural stem cells restored memory and enhanced synaptic function in two animal models relevant to Alzheimer’s disease. Importantly, these results did not require reduction in beta amyloid or tau, substances that accumulate in the brains of patients with Alzheimer’s disease and account for the pathological hallmarks of the disease. The data was presented at the Alzheimer’s Association International Conference 2012 in Vancouver, Canada.

In July 2012, CIRM approved an award to us for up to a $20 million under the Disease Team Therapy Development Award program (RFA 10-05). The award is to fund preclinical development of our HuCNS-SC cells in cervical spinal cord injury over a maximum four-year period, with the goal of filing an IND in that time. Funding under the award is expected to be in the form of forgivable loans, the terms and conditions for which must be mutually agreed by CIRM and us.

In July 2012, the Japan Patent Office granted us Patent Number 5007003 which broadly covers the prospective isolation and enrichment of neural stem and progenitor cells using antibody selection, as well as the use of these cells to treat disorders of the central nervous system. Some of the more noteworthy claims in this patent include methods for isolating human neural stem cells, as well as compositions of matter comprising enriched neural stem cells, such as our proprietary HuCNS-SC cells, and the use of enriched neural stem cells as a medicament for the treatment of neurodegenerative diseases, acute brain injury and dysfunction of the central nervous system. The term of this patent extends into 2020.

In September 2012, we presented interim six-month data from the first patient cohort in our Phase I/II clinical trial of our HuCNS-SC cells for chronic spinal cord injury. The first patient cohort all have no sensory or motor function below the level of injury and are considered to have complete spinal cord injuries. The interim data continues to demonstrate a favorable safety profile, and showed considerable gains in sensory function in two of the three patients compared to pre-transplant baselines; the third patient remained stable. The data was presented at the 51st Annual Scientific Meeting of the International Spinal Cord Society in London, England.

Also in September 2012, the first patient with an incomplete spinal cord injury was enrolled and dosed in our Phase I/II clinical trial in chronic spinal cord injury. This is the first patient in the second cohort of the trial, which will be comprised of four patients who retain some sensory function below the level of trauma and are therefore considered to have an incomplete injury.

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In September 2012, CIRM approved a second disease team award to us for up to $20 million under RFA 10-05. This second award is to fund preclinical development of our HuCNS-SC cells in Alzheimer’s disease over a maximum four-year period, with the goal of filing an IND in that time. Funding for this award is also expected to be in the form of a forgivable loan, the terms and conditions for which must be mutually agreed by CIRM and us.

In October 2012, the first patient in our Phase I/II clinical trial in dry age-related macular degeneration (AMD) was enrolled and dosed. AMD afflicts approximately 30 million people worldwide and is the leading cause of vision loss and blindness in people over 55 years of age. Our preclinical data, which was published in the peer reviewed European Journal of Neuroscience, demonstrated that our HuCNS-SC cells protect host photoreceptors and preserve vision in a well-established animal model of retinal disease. Moreover, the number of cone photoreceptors remained constant over an extended period, consistent with the sustained visual acuity and light sensitivity observed in the study. In humans, degeneration of the cone photoreceptors accounts for the unique pattern of vision loss in dry AMD.

In October 2012, two papers reporting clinical and preclinical data demonstrating the therapeutic potential of our proprietary HuCNS-SC cells for a range of myelination disorders were published in Science Translational Medicine, the peer review journal of the American Association for the Advancement of Science. The first paper summarized the data from our Phase I trial in Pelizeus-Merzbacher Disease (PMD), which showed preliminary evidence of progressive and durable donor cell-derived myelination in all four patients transplanted with HuCNS-SC cells. Three of the four patients showed modest gains in neurological function; the fourth patient remained stable. These gains may represent signals of a clinical effect from the HuCNS-SC cells and warrant further investigation in a controlled trial. The second paper demonstrated that transplantation of our neural stem cells in an animal model of severe myelin deficiency results in new, functional myelin. Sophisticated analytical techniques were used to confirm that changes measured by magnetic resonance images were in fact derived from new human myelin generated by the transplanted HuCNS-SC cells and these results supported the use of similar techniques to detect and evaluate the degree of myelination in our Phase I PMD trial.

In October 2012, we were issued U.S. Patent Number 8,283,164 which broadly covers purified populations of human liver cells, including our human liver engrafting cells (hLEC). The hLEC cells were first isolated by our researchers in the late 1990s, and our scientists have repeatedly demonstrated the cells’ engraftment and robust bioactivity in vivo and that they are expandable. While our hLEC cells are purified from donated adult livers not suitable for transplant, the newly issued’ 164 patent claims cells independent of tissue source, and therefore, has potential relevance to those deriving liver cells from induced pluripotent or embryonic stem cell platforms. The term of the’ 164 patent extends into 2022.

In October 2012, we launched four new SC Proven human neural stem cell kits for use in neuroscience research. Each kit will contain high purity, multipotent neural stem cells derived from a different area of the human central nervous system, and will provide researchers with a reproducible and scalable serum-free platform with which to perform a broad range of assays. With these kits, researchers will now have the ability to compare and contrast the biological, functional and neural differentiation properties of human neural stem cells isolated from specific regions of the central nervous system, as well as to screen for the effects of different compounds on such cells.

In October 2012 we partnered with an UK-based biomedical company, to develop and commercialize a range of cell lines and reagents to facilitate iPS cell-based research for regenerative medicine applications. The first product under the partnership, an “ultra-primary” human fibroblast cell line from which researchers can generate iPS cell lines, was launched under the SC Proven brand.

Critical Accounting Policies and the Use of Estimates

The accompanying discussion and analysis of our financial condition and results of operations are based on our condensed consolidated financial statements and the related disclosures, which have been prepared in accordance with U.S. GAAP. The preparation of these condensed consolidated financial statements requires management to make estimates, assumptions, and judgments that affect the reported amounts in our condensed consolidated financial statements and accompanying notes. These estimates form the basis for making judgments about the carrying values of assets and liabilities. We base our estimates and judgments on historical experience and on various other assumptions that we believe to be reasonable under the circumstances, and we have established internal controls related to the preparation of these estimates. Actual results and the timing of the results could differ materially from these estimates.

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Stock-Based Compensation

U.S. GAAP requires us to recognize expense related to the fair value of our stock-based payment awards, including employee stock options and restricted stock units. Under the provisions of U.S. GAAP, the fair value of our employee stock-based payment awards is estimated at the date of grant using the Black-Scholes-Merton (Black-Scholes) option-pricing model and is recognized as expense ratably over the requisite service period. The Black-Scholes option-pricing model requires the use of certain assumptions, the most significant of which are our estimates of the expected volatility of the market price of our stock and the expected term of the award. Our estimate of the expected volatility is based on historical volatility. The expected term represents our estimated period during which our stock-based awards remain outstanding. We estimate the expected term based on historical experience of similar awards, giving consideration to the contractual terms of the awards, vesting requirements, and expectation of future employee behavior, including post-vesting terminations.

We review our valuation assumptions at each grant date and, as a result, our assumptions in future periods may change. As of September 30, 2012, we expect to recognize approximately $2,835,000 of compensation expense related to unvested stock-based awards over a weighted-average period of 1.9 years. See also Note 5, “Stock-Based Compensation,” in the notes to condensed consolidated financial statements of Part I, Item 1 of this Form 10-Q for further information.

Wind-down expenses — Rhode Island

In connection with exiting our research and manufacturing operations in Lincoln, Rhode Island, and the relocation of our corporate headquarters and remaining research laboratories to California in October 1999, we provided a reserve for our estimate of the exit cost obligation. The reserve reflects estimates of the ongoing costs of our former scientific and administrative facility in Lincoln, which we hold on a lease that terminates on June 30, 2013. We are seeking to sublease, assign, sell, or otherwise divest ourselves of our interest in the facility at the earliest possible time, but we cannot determine with certainty a fixed date by which such events will occur, if at all.

In determining the facility exit cost reserve amount, we are required to consider our lease payments through to the end of the lease term and estimate other relevant factors such as facility operating expenses, real estate market conditions in Rhode Island for similar facilities, occupancy rates, and sublease rental rates projected over the course of the leasehold. We re-evaluate the estimate each quarter, taking account of changes, if any, in each underlying factor. The process is inherently subjective because it involves projections over time — from the date of the estimate through the end of the lease — and it is not possible to determine any of the factors, except the lease payments, with certainty over that period.

Management forms its best estimate on a quarterly basis, after considering actual sublease activity, reports from our broker/realtor about current and predicted real estate market conditions in Rhode Island, the likelihood of new subleases in the foreseeable future for the specific facility and significant changes in the actual or projected operating expenses of the property. We discount the projected net outflow over the term of the leasehold to arrive at the present value, and adjust the reserve to that figure. The estimated vacancy rate for the facility is an important assumption in determining the reserve because changes in this assumption have the greatest effect on estimated sublease income. In addition, the vacancy rate estimate is the variable most subject to change, while at the same time it involves the greatest judgment and uncertainty due to the absence of highly predictive information concerning the future of the local economy and future demand for specialized laboratory and office space in that area. The average vacancy rate of the facility over the last nine years (2003 through 2011) was approximately 73%, varying from 62% to 89%. As of September 30, 2012, based on current information available to management, the vacancy rate is projected to be approximately 71% for 2012 and 89% in 2013 (the lease ends on June 30, 2013). These estimates are based on actual occupancy as of September 30, 2012, predicted lead time for acquiring new subtenants, historical vacancy rates for the area, and assessments by our broker/realtor of future real estate market conditions. Due to the short time remaining on the lease period, the reserve assumes no additional tenants from 2012 to the end of the lease. If the assumed operating expenses for the remainder of the lease had been 5% higher or lower at September 30, 2012, then the reserve would have increased or decreased by approximately $25,000. Management does not wait for specific events to change its estimate, but instead uses its best efforts to anticipate them on a quarterly basis. See Note 6 “Wind-Down Expenses,” in the notes to condensed consolidated financial statements of Part I, Item 1 of this Form 10-Q for further information.

Business Combinations

The operating results of acquired companies or operations are included in our consolidated financial statements starting on the date of acquisition. Goodwill is recorded at the time of an acquisition and is calculated as the difference between the aggregate consideration paid for an acquisition and the fair value of the net tangible and intangible assets acquired.

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Accounting for acquisitions requires extensive use of accounting estimates and judgments to allocate the purchase price to the fair value of the net tangible and intangible assets acquired, including in-process research and development. Goodwill and intangible assets deemed to have indefinite lives are not amortized but are subject to annual impairment tests. If the assumptions and estimates used to allocate the purchase price are not correct, or if business conditions change, purchase price adjustments or future asset impairment charges could be required. We test goodwill for impairment on an annual basis or more frequently if we believe indicators of impairment exist. Impairment evaluations involve management estimates of asset useful lives and future cash flows. Significant management judgment is required in the forecasts of future operating results that are used in the evaluations. It is possible, however, that the plans and estimates used may be incorrect. If our actual results, or the plans and estimates used in future impairment analysis, are lower than the original estimates used to assess the recoverability of these assets, we could incur impairment charges in a future period.

Warrant Liability

We account for our warrants in accordance with U.S. GAAP which defines how freestanding contracts that are indexed to and potentially settled in a company’s own stock should be measured and classified. Authoritative accounting guidance prescribes that only warrants issued by us under contracts that cannot be net-cash settled, and are both indexed to and settled in our common stock, can be classified as equity. As part of both our November 2008 and November 2009 financings, we issued warrants with five year terms to purchase 1,034,483 and 400,000 shares of our common stock at $23.00 and $15.00 per share, respectively. As part of our December 2011 financing, we issued Series A Warrants with a five year term to purchase 8,000,000 shares at $1.40 per share and Series B Warrants with a ninety trading day term to purchase 8,000,000 units at $1.25 per unit. Each unit underlying the Series B Warrants consisted of one share of our common stock and one Series A warrant. In the first and second quarter of 2012, an aggregate of 2,700,000 Series B Warrants were exercised. For the exercise of these warrants, we issued 2,700,000 shares of our common stock and 2,700,000 Series A Warrants with an exercise price of $1.40 per share. The remaining 5,300,000 Series B Warrants expired unexercised by their terms on May 2, 2012. As terms of the warrants issued in 2008 and 2009, as well as the Series A and Series B warrants, do not meet the specific conditions for equity classification, we are required to classify the fair value of these warrants as a liability, with subsequent changes in fair value to be recorded as income (loss) on change in fair value of warrant liability. The fair value of the warrants issued in the 2008 and 2009 financings is determined using the Black-Scholes-Merton (Black-Scholes) option pricing model and the fair value of the Series A and Series B Warrants is determined using a Monte Carlo simulation model (see Note 8, “Warrant Liability”). The fair value is affected by changes in inputs to these models including our stock price, expected stock price volatility, the contractual term, and the risk-free interest rate. The use of a Monte Carlo simulation model requires input of additional assumptions including the progress of our R&D programs and its affect on potential future financings. We will continue to classify the fair value of the warrants as a liability until the warrants are exercised, expire or are amended in a way that would no longer require these warrants to be classified as a liability.

Revenue Recognition

We currently recognize revenue resulting from the licensing and use of our technology and intellectual property, from government grants, from services provided to third parties, and from product sales. Licensing agreements may contain multiple elements, such as upfront fees, payments related to the achievement of particular milestones and royalties. Revenue from upfront fees for licensing agreements that contain multiple elements are generally deferred and recognized on a straight-line basis over the term of the agreement. Fees associated with substantive at risk performance-based milestones are recognized as revenue upon completion of the scientific or regulatory event specified in the agreement, and royalties received are recognized as earned. Revenue from licensing agreements is recognized net of a fixed percentage due to licensors as royalties. Grant revenue from government agencies are funds received to cover specific expenses and are recognized as earned upon either the incurring of reimbursable expenses directly related to the particular research plan or the completion of certain development milestones as defined within the terms of the relevant collaborative agreement or grant. Revenue from services provided to third parties is recognized when we have performed the agreed upon services. Revenue from product sales are recognized when the product is shipped and the order fulfilled.

Results of Operations

Our results of operations have varied significantly from year to year and quarter to quarter and may vary significantly in the future due to the occurrence of material recurring and nonrecurring events, including without limitation the receipt and payment of recurring and nonrecurring licensing payments, the initiation or termination of clinical studies, research collaborations and development programs for both cell-based therapeutic products and research tools, unpredictable or unanticipated manufacturing and supply costs, unanticipated capital expenditures necessary to support our business, expenses

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arising out of the integration of the acquired SCS operations, developments in on-going patent prosecution and litigation, the on-going expenses to lease and maintain our Rhode Island facilities, and the costs associated with operating our California and Cambridge, U.K. facilities.

We acquired the operations of SCS on April 1, 2009, and have consolidated such operations since that date.

Revenue and Cost of Product Sales

Revenue for the three and nine-month periods ended September 30, 2012, as compared with the same period in 2011, is summarized in the table below:

	Three months ended, September 30				Change in 2012 versus 2011					Nine months ended, September 30				Change in 2012 versus 2011
	2012		2011		$		%			2012		2011		$		%
Revenue:
Licensing agreements, grants and other	$	60,739	$	41,265	$	19,474		47	%	$	471,501	$	162,614	$	308,887		190	%
Product sales		203,256		182,321		20,935		11	%		685,364		516,536		168,828		33	%
Total revenue		263,995		223,586		40,409		18	%		1,156,865		679,150		477,715		70	%
Cost of product sales		71,891		60,501		11,390		19	%		208,127		167,390		40,737		24	%
Gross profit	$	192,104	$	163,085	$	29,019		18	%	$	948,738	$	511,760	$	436,978		85	%

Third quarter ended September 30, 2012 versus third quarter ended September 30, 2011. Total revenue in the third quarter of 2012 was approximately $264,000, which was 18% higher than total revenue of approximately $224,000 in the third quarter of 2011. In the third quarter of 2012, revenue from product sales was approximately $203,000, which was 11% higher, compared to the same period in 2011. This increase was primarily attributable to increased unit volumes in our SC Proven line of media and reagents. Licensing, grant and other revenue in the third quarter of 2012 totaled approximately $61,000, which was 47% higher compared to the same period in 2011. The increase was primarily attributable to revenue from services provided to third parties.

Nine-month period ended September 30, 2012 versus nine-month period ended September 30, 2011. Total revenue in the nine-month period ended September 30, 2012 was approximately $1,157,000, which was 70% higher than total revenue of approximately $679,000 in the same period of 2011. In the nine-month period ended 2012, revenue from product sales was approximately $685,000, which was 33% higher, compared to the same period in 2011. This increase was primarily attributable to increased unit volumes in our SC Proven line of media and reagents. Licensing, grant and other revenue in the nine-month period ended 2012 totaled approximately $472,000, which was 190% higher compared to the same period in 2011. This increase was primarily attributable to licensing fees from a license agreement with genOway, under which we granted genOway a worldwide exclusive license to our IRES technology for use in the development and commercialization of genetically engineered mice.

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Operating Expenses

Operating expenses for the three and nine-month periods ended September 30, 2012, as compared with the same period in 2011, is summarized in the table below:

	Three months ended, September 30				Change in 2012 versus 2011						Nine months ended, September 30				Change in 2012 versus 2011
	2012		2011		$			%			2012		2011		$			%
Operating expenses:
Research & development	$	3,478,142	$	4,524,334	$	(1,046,192	)		(23	)%	$	11,165,599	$	15,103,845	$	(3,938,246	)		(26	)%
Selling, general & administrative		1,636,438		1,733,229		(96,791	)		(6	)%		5,336,105		5,912,220		(576,115	)		(10	)%
Wind-down expenses		154,742		68,694		86,048			125	%		199,799		258,749		(58,950	)		(23	)%
Total operating expenses	$	5,269,322	$	6,326,257	$	(1,056,935	)		(17	)%	$	16,701,503	$	21,274,814	$	(4,573,311	)		(22	)%

Research and Development Expenses

Our R&D expenses consist primarily of salaries and related personnel expenses, costs associated with clinical trials and regulatory submissions, costs associated with preclinical activities such as toxicology studies, costs associated with cell processing and process development, certain patent-related costs such as licensing, facilities related costs such as depreciation, lab equipment and supplies. Clinical trial expenses include payments to vendors such as clinical research organizations, contract manufacturers, clinical trial sites, laboratories for testing clinical samples and consultants. Cumulative R&D costs incurred since we refocused our activities on developing cell-based therapeutics (fiscal years 2000 through the nine months ended September 30, 2012) were approximately $163 million. Over this period, the majority of these cumulative costs were related to: (i) characterization of our proprietary HuCNS-SC cells, (ii) expenditures for toxicology and other preclinical studies, preparation and submission of applications to regulatory agencies to conduct clinical trials and obtaining regulatory clearance to initiate such trials, all with respect to our HuCNS-SC cells, (iii) preclinical studies and development of our human liver engrafting cells, (iv) costs associated with cell processing and process development, and (v) costs associated with our clinical studies.

We use and manage our R&D resources, including our employees and facilities, across various projects rather than on a project-by-project basis for the following reasons. The allocations of time and resources change as the needs and priorities of individual projects and programs change, and many of our researchers are assigned to more than one project at any given time. Furthermore, we are exploring multiple possible uses for each of our proprietary cell types, so much of our R&D effort is complementary to and supportive of each of these projects. Lastly, much of our R&D effort is focused on manufacturing processes, which can result in process improvements useful across cell types. We also use external service providers to assist in the conduct of our clinical trials, to manufacture certain of our product candidates and to provide various other R&D related products and services. Many of these costs and expenses are complementary to and supportive of each of our programs. Because we do not have a development collaborator for any of our product programs, we are currently responsible for all costs incurred with respect to our product candidates.

Third quarter ended September 30, 2012 versus third quarter ended September 30, 2011. R&D expenses totaled approximately $3,478,000 in the third quarter of 2012 compared with $4,524,000 in the third quarter of 2011. The decrease of 23%, or approximately $1,046,000, in 2012 compared to 2011, was primarily attributable to (i) a decrease of approximately $211,000 in personnel expenses, (ii) a decrease of approximately $67,000 in operating expenses at our U.K. operations as we consolidated our activities at the site, (iii) a decrease in facilities expense of approximately $296,000 attributable to the relocation of our corporate headquarters and core research activities in July 2011; the third quarter of 2011 includes facilities expense from the previous lease which expired on August 31, 2011, (iv) a decrease of approximately $378,000 in external services and clinical studies; the third quarter of 2011 includes higher external services expenses primarily related to continuing preclinical studies of our HuCNS-SC cells for retinal disorders, other potential indications and quality tests of our working cell banks, and (v) a decrease in other operating expenses of approximately $94,000.

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Nine-month period ended September 30, 2012 versus nine-month period ended September 30, 2011. R&D expenses totaled approximately $11,166,000 in the nine-month period ended September 30, 2012 compared with $15,104,000 for the same period in 2011. The decrease of 26%, or approximately $3,938,000, in 2012 compared to 2011, was primarily attributable to (i) a decrease of approximately $1,136,000 in personnel expenses due to the reduction in workforce effected in May 2011, (ii) a decrease of approximately $316,000 in operating expenses at our U.K. operations as we consolidated our activities at the site, (iii) a decrease in facilities expense of approximately $922,000 attributable to the relocation of our corporate headquarters and core research activities in July 2011; the nine-month period of 2011 includes facilities expense from the previous lease which expired on August 31, 2011, (iv) a decrease of approximately $1,103,000 in external services and clinical studies; the nine-month period of 2011 includes higher external services expenses primarily related to continuing preclinical studies of our HuCNS-SC cells for retinal disorders, other potential indications and quality tests of our working cell banks, and (v) a decrease in supplies and other operating expenses of approximately $461,000.

Selling, General and Administrative Expenses

Selling, general and administrative (SG&A) expenses are primarily comprised of salaries, benefits and other staff related costs associated with sales and marketing, finance, legal, human resources, information technology, and other administrative personnel, facilities and overhead costs, external legal and other external general and administrative services.

Third quarter ended September 30, 2012 versus third quarter ended September 30, 2011. SG&A expenses totaled approximately $1,636,000 in the third quarter of 2012 compared with approximately $1,733,000 in the third quarter of 2011. The decrease of approximately $97,000, or 6%, in 2012 compared to 2011, was primarily attributable to a decrease in facilities expense attributable to the relocation of our corporate headquarters in July 2011; the third quarter of 2011 includes facilities expense from the previous lease which expired on August 31, 2011.

Nine-month period ended September 30, 2012 versus nine-month period ended September 30, 2011. SG&A expenses totaled approximately $5,336,000 in the nine-month period ended September 30 2012 compared with approximately $5,912,000 in the same period of 2011. The decrease of approximately $576,000, or 10%, in 2012 compared to 2011, was primarily attributable to (i) a decrease of approximately $179,000 in personnel expenses primarily due to the reduction in workforce effected in May 2011, (ii) a decrease of approximately $242,000 in external services and (iii) a decrease in facilities expense of approximately $163,000 attributable to the relocation of our corporate headquarters in July 2011; the third quarter of 2011 includes facilities expense from the previous lease which expired on August 31, 2011. The above decreases were partially offset by an increase in other operating expenses of approximately $8,000.

Wind-down Expenses

In 1999, in connection with exiting our former research facility in Rhode Island, we created a reserve for the estimated lease payments and operating expenses related to it. The reserve has been re-evaluated and adjusted based on assumptions relevant to real estate market conditions and the estimated time until we could either fully sublease, assign or sell our remaining interests in the property. The reserve was approximately $2,135,000 at December 31, 2011. Payments net of subtenant income of approximately $300,000, $280,000 and $284,000 for the first, second and third quarter of 2012 respectively were recorded against this reserve. We re-evaluated the estimate at the end of each quarter in 2012 and adjusted the reserve to approximately $1,318,000 by recording in aggregate, additional wind-down expenses of approximately $200,000. For the similar period in 2011, payments recorded against the reserve were approximately $317,000, $301,000 and $308,000 for the first, second and third quarter respectively, and to adjust the reserve, we recorded in aggregate additional wind-down expenses of approximately $259,000. Expenses for this facility will fluctuate based on changes in tenant occupancy rates and other operating expenses related to the lease. Even though it is our intent to sublease, assign, sell, or otherwise divest ourselves of our interests in the facility at the earliest possible time, we cannot determine with certainty a fixed date by which such events will occur. In light of this uncertainty, based on estimates, we will periodically re-evaluate and adjust the reserve, as necessary. See Note 6 “Wind-down expenses,” in the notes to condensed consolidated financial statements of Part I, Item 1 of this Form 10-Q for further information.

Other Income (Expense)

Other expense totaled approximately $11,260,000 in the third quarter of 2012 compared with other income of $1,829,000 in the same period of 2011, and other expense of $9,980,000 for the nine-month period ended September 30, 2012 compared with other income of approximately $6,646,000 for the nine-month period ended September 30, 2011.

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	Three months ended, September 30						Change in 2012 versus 2011						Nine months ended, September 30						Change in 2012 versus 2011
	2012			2011			$			%			2012			2011			$			%
Other income (expense):
Change in fair value of warrant liability	$	(11,239,465	)	$	1,697,194		$	(12,936,659	)		(762	)%	$	(9,974,685	)	$	6,500,377		$	(16,475,062	)		(253	)%
Realized gain on sale of marketable securities		—			—			—			—			—			83,750			(83,750	)		(100	)%
Interest income		2,372			3,514			(1,142	)		(33	)%		9,393			11,332			(1,939	)		(17	)%
Interest expense		(11,392	)		(16,585	)		5,193			(31	)%		(40,014	)		(56,585	)		16,571			(29	)%
Other income (expense), net		(11,087	)		144,697			(155,784	)		(108	)%		25,364			107,400			(82,036	)		(76	)%
Total other income (expense)	$	(11,259,572	)	$	1,828,820		$	(13,088,392	)		(716	)%	$	(9,979,942	)	$	6,646,274		$	(16,626,216	)		(250	)%

Change in Fair Value of Warrant Liability

We record changes in fair value of warrant liability as income or loss in our Consolidated Statements of Operations. We have warrants outstanding which were issued as part of several transactions since 2008 and have classified all these warrants as a liability. The fair value of the outstanding warrants is determined using various option pricing models, such as the Black-Scholes-Merton (Black-Scholes) option pricing model and a Monte Carlo simulation model, and is affected by changes in inputs to the various models, including our stock price, expected stock price volatility, the contractual term and the risk-free interest rate. The use of a Monte Carlo simulation model requires input of additional subjective assumptions including the progress of our R&D programs and its affect on potential future financings. The fair value of the warrant liability is revalued at the end of each reporting period. See Note 8 “Warrant Liability” in the notes to condensed consolidated financial statements of Part I, Item 1 of this Form 10-Q for further information.

Interest Income

Interest income in the three and nine-month period ended September 30, 2012 and 2011 were not significant due to low average yields.

Interest Expense

Interest expense decreased by approximately $5,000 or 31% in the third quarter of 2012, and $17,000 or 29% for the nine-month period ended September 30, 2012, when compared to the same periods in 2011. Interest expense is primarily for outstanding debt and capital lease balances. See Note 7 “Commitment and Contingencies,” in the notes to condensed consolidated financial statements of Part I, Item 1 of this Form 10-Q for further information.

Other income (expense), net

Other expense for the third quarter of 2012 is primarily for state franchise taxes and other income for the nine-month period ended September 30, 2012 includes approximately $63,000 of R&D tax credits due to our wholly-owned subsidiary Stem Cell Sciences (U.K.) Ltd. The above income was offset by other expenses primarily related to state franchise taxes. Other income for the three and nine month periods in 2011 include the receipt of approximately $150,000 as a break-up fee paid to us upon the expiration of an exclusivity period granted to a potential licensee, which was partially offset by other expenses, primarily state franchise taxes.

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Liquidity and Capital Resources

Since our inception, we have financed our operations through the sale of common and preferred stock, the issuance of long-term debt and capitalized lease obligations, revenue from collaborative agreements, research grants, license fees, and interest income.

	September 30, 2012		December 31, 2011		Change
					$		%
Cash and cash equivalents	$	15,712,688	$	13,311,261	$	2,401,427		18	%

In summary, our cash flows were:

	Nine months ended September 30,						Change in 2012 versus 2011
	2012			2011			$		%
Net cash used in operating activities	$	(14,949,810	)	$	(16,845,564	)	$	1,895,754		(11	)%
Net cash used in investing activities	$	(2,767,662	)	$	(5,378,064	)	$	2,610,402		(49	)%
Net cash provided by financing activities	$	20,131,310		$	9,852,060		$	10,279,250		104	%

Net Cash Used in Operating Activities

Net cash used in operating activities in the nine-month period ended September 30, 2012 decreased by approximately $1,896,000, or 11%, when compared to the same period of 2011. Cash used in operating activities is primarily driven by our net loss as adjusted for non-cash charges and differences in the timing of operating cash flows.

Net Cash Provided by (Used in) Investing Activities

Net cash used in investing activities decreased by approximately $2,610,000, or 49%, from 2011 to 2012. The decrease was primarily attributable to (i) a decrease in net purchases of short-term marketable debt securities of approximately $2,342,000 and (ii) a decrease in net capital expenditures of approximately $268,000.

Net Cash Provided by Financing Activities

Net cash provided by financing activities in the nine-month period ended September 30, 2012 increased by approximately $10,279,000, or 104%, compared to the same period in 2011.

For the nine months ended September 30, 2012, we had the following significant financing transactions:

• Sale of 7,956,061 shares of our common stock at an average price per share of $2.10 for gross proceeds of approximately $16,738,000. These sales were made under a sales agreement entered into in June 2009 and the sales agent is paid compensation equal to 3% of gross proceeds pursuant to the terms of the agreement. The shares were offered under our shelf registration statement previously filed with, and declared effective by, the SEC.

• An aggregate of 1,800,000 Series B Warrants were exercised and we received gross proceeds of $2,250,000. The remaining 5,300,000 Series B Warrants expired unexercised by their terms on May 2, 2012. For the exercise of these warrants, we issued 1,800,000 shares of our common stock and 1,800,000 Series A Warrants. The Series A Warrants have an initial exercise price of $1.40 per share and will expire on the fifth anniversary of the closing date of the initial financing transaction in December 2011.

• An aggregate of 1,445,400 Series A Warrants were exercised. For the exercise of these warrants, we issued 1,445,400 shares of our common stock and received gross proceeds of $977,900 and $1,045,660 in the third and fourth quarter of 2012 respectively.

For the similar period in 2011, we had the following significant transactions:

• Sale of 1,000,000 shares of our common stock to selected institutional investors at a price of $10.00 per share. We received net proceeds, after deducting offering expenses and fees, of approximately $9,400,000.

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The investors were also granted an option to purchase an additional 600,000 shares at $10.00 per share. The option was not exercised and expired on February 18, 2011. The shares were offered under a shelf registration previously filed with, and declared effective by, the SEC.

• Sale of 423,216 shares of our common stock at an average price per share of $2.58 for gross proceeds of approximately $1,093,000. These shares were sold under a sales agreement entered into in June 2009 and the sales agent is paid compensation equal to 3% of gross proceeds pursuant to the terms of the agreement. The shares were offered under a shelf registration previously filed with, and declared effective by, the SEC.

We have incurred significant operating losses and negative cash flows since inception. We have not achieved profitability and may not be able to realize sufficient revenue to achieve or sustain profitability in the future. We do not expect to be profitable in the next several years, but rather expect to incur additional operating losses. We have limited liquidity and capital resources and must obtain significant additional capital resources in order to sustain our product development efforts, for acquisition of technologies and intellectual property rights, for preclinical and clinical testing of our therapeutic products, pursuit of regulatory approvals, acquisition of capital equipment, laboratory and office facilities, establishment of production capabilities, for selling, general and administrative expenses and other working capital requirements. We rely on cash balances and proceeds from equity and debt offerings, proceeds from the transfer or sale of our intellectual property rights, equipment, facilities or investments, government grants, and funding from collaborative arrangements, if obtainable, to fund our operations.

We intend to pursue opportunities to obtain additional financing in the future through equity and debt financings, grants and collaborative research arrangements. In November 2010, we filed with the SEC, and the SEC declared effective, a universal shelf registration statement which permits us to issue up to $100 million worth of registered debt and equity securities. As of October 30, 2012, we had approximately $26 million under this universal shelf registration statement available for issuing debt or equity securities. Under this effective shelf registration, we have the flexibility to issue registered securities, from time to time, in one or more separate offerings or other transactions with the size, price and terms to be determined at the time of issuance. Registered securities issued using this shelf may be used to raise additional capital to fund our working capital and other corporate needs, for future acquisitions of assets, programs or businesses, and for other corporate purposes.

The source, timing and availability of any future financing will depend principally upon market conditions, interest rates and, more specifically, on our progress in our exploratory, preclinical and future clinical development programs. Funding may not be available when needed — at all, or on terms acceptable to us. Lack of necessary funds may require us, among other things, to delay, scale back or eliminate some or all of our research and product development programs, planned clinical trials, and/or our capital expenditures or to license our potential products or technologies to third parties. In addition, the decline in economic activity, together with the deterioration of the credit and capital markets, could have an adverse impact on potential sources of future financing.

Commitments

See Note 7, “Commitments and Contingencies” in the notes to condensed consolidated financial statements of Part I, Item 1 of this Form 10-Q for further information.

Off-Balance Sheet Arrangements

We have certain contractual arrangements that create potential risk for us and are not recognized in our Consolidated Balance Sheets. Discussed below are those off-balance sheet arrangements that have or are reasonably likely to have a material current or future effect on our financial condition, changes in financial condition, revenue or expenses, results of operations, liquidity, capital expenditures or capital resources.

Operating Leases

We lease various real properties under operating leases that generally require us to pay taxes, insurance, maintenance, and minimum lease payments. Some of our leases have options to renew.

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Operating Leases — California

In September 2010, we entered into a two-year sublease agreement with Caliper Life Sciences, Inc., for approximately 13,200 square feet in a facility located in Mountain View, California. In June 2012, we extended the sublease term to September 30, 2013. We will pay approximately $1,081,000 in aggregate as rent over the term of the lease.

In December 2010, we entered into a commercial lease agreement with BMR-Gateway Boulevard LLC (“BMR”), as landlord, for approximately 43,000 square feet of office and research space at BMR’s Pacific Research Center in Newark, California. The initial term of the lease is approximately eleven and one-half years, and we relocated our corporate headquarters and core research activities from a facility located at the Stanford Research Park in Palo Alto, California, to this facility in July 2011. The lease for the Palo Alto facility expired on August 31, 2011. We will pay approximately $17,869,000 in aggregate as rent over the term of the lease, which we recognize as operating lease expense on a straight-line basis. Deferred rent was approximately $1,374,000 as of September 30, 2012, and approximately $1,301,000 as of December 31, 2011. We constructed laboratories, offices and related infrastructure within the leased space during the first several months of the lease. As part of the lease, BMR has agreed to provide various financial allowances so that we can build initial and future laboratories, offices and other improvements, subject to customary terms and conditions relating to landlord-funded tenant improvements. As part of the lease, we have, until January 2013, an option to lease up to an additional 30,000 square feet in the building.

Operating Leases — Rhode Island

We entered into a fifteen-year lease agreement for a scientific and administrative facility (SAF) in Rhode Island in connection with a sale and leaseback arrangement in 1997. The lease term expires June 30, 2013 and includes escalating rent payments which we recognize on a straight-line basis. Deferred rent expense for this facility was approximately $299,000 at September 30, 2012 and $452,000 at December 31, 2011, and is included as part of the wind-down accrual on the accompanying condensed consolidated balance sheets. For the year 2012, we expect to pay approximately $1,172,000 in operating lease payments and estimated operating expenses of approximately $690,000, before receipt of sub-tenant income and we expect to receive, in aggregate, approximately $412,000 in sub-tenant rent and operating expenses. As a result of the above transactions, our estimated cash outlay net of sub-tenant rent for the SAF will be approximately $1,450,000 for 2012.

Operating Leases — United Kingdom

In January 2011, we amended the existing lease agreements of our wholly-owned subsidiary, Stem Cell Sciences (U.K.) Ltd, effectively reducing our leased space from approximately 5,000 square feet to approximately 1,900 square feet of office and lab space. The lease by its terms was extended to September 30, 2013. We expect to pay approximately 61,000 GBP as rental payments for 2012. StemCells, Inc. is the guarantor of Stem Cell Sciences (U.K.) Ltd’s obligations under the existing lease.

With the exception of the leases discussed above, we have not entered into any off balance sheet financial arrangements and have not established any special purpose entities. We have not guaranteed any debts or commitments of other entities or entered into any options on non-financial assets.

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Contractual Obligations

In the table below, we set forth our legally binding and enforceable contractual cash obligations at September 30, 2012:

	Total Obligations at September 30, 2012		Payable in (October to December) 2012		Payable in 2013		Payable in 2014		Payable in 2015		Payable in 2016		Payable in 2017 and Beyond
Operating lease payments(1)	$	17,945,016	$	767,557	$	2,538,660	$	1,529,890	$	1,581,352	$	1,627,668	$	9,899,889
Capital lease payment (equipment)		23,560	$	2,019	$	8,078	$	8,078	$	5,385		—		—
Bonds Payable (principal & interest)(2)		434,249		59,804		237,593		136,852		—		—		—
Total contractual cash obligations	$	18,402,825	$	829,380	$	2,784,331	$	1,674,820	$	1,586,737	$	1,627,668	$	9,899,889

(1) Operating lease payments exclude space-sharing and sub-lease income (see “Off-Balance Sheet Arrangements — Operating Leases” above for further information), but include rent payments for our Rhode Island facility that are included as part of our “Accrued wind-down expenses” in our condensed consolidated financial statements. See Note 6, “Wind-down expenses” and Note 7, “Commitments and Contingencies” in the notes to condensed consolidated financial statements of Part I, Item 1 of this Form 10-Q for further information.

(2) See Note 7, “Commitments and Contingencies” in the notes to condensed consolidated financial statements of Part I, Item 1 of this Form 10-Q for further information.

Under license agreements with NeuroSpheres, Ltd., we obtained an exclusive patent license covering all uses of certain neural stem cell technology. We made up-front payments to NeuroSpheres of 6,500 shares of our common stock and $50,000, and will make additional cash payments as stated milestones are achieved. Effective in 2004, we were obligated to pay annual payments of $50,000, creditable against certain royalties. Effective in 2008, as part of the indemnification agreement with NeuroSpheres described above, we offset the annual $50,000 obligation against litigation costs incurred under that agreement.

We periodically enter into licensing agreements with third parties to obtain exclusive or non-exclusive licenses for certain technologies. The terms of certain of these agreements require us to pay future milestone payments based upon achievement of certain developmental, regulatory or commercial milestones. We do not anticipate making any milestone payments under any of our licensing agreements for 2012. Milestone payments beyond fiscal year 2012 cannot be predicted or estimated, due to the uncertainty of achieving the required developmental, regulatory or commercial milestones.

We do not have any material unconditional purchase obligations or commercial commitments related to capital expenditures, clinical development, clinical manufacturing, or other external services contracts at September 30, 2012.

ITEM 3. QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK

Our market risks at September 30, 2012 have not changed materially from those discussed in Item 7A of our Form 10-K for the year ended December 31, 2011 on file with the U.S. Securities and Exchange Commission.

See also Note 2, “Financial Assets,” in the notes to condensed consolidated financial statements in Part I, Item 1 of this Form 10-Q.

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ITEM 4. CONTROLS AND PROCEDURES

In response to the requirement of the Sarbanes-Oxley Act of 2002, as of the end of the period covered by this report, our chief executive officer and chief financial officer, along with other members of management, reviewed the effectiveness of the design and operation of our disclosure controls and procedures. Such controls and procedures are designed to ensure that information required to be disclosed in the Company’s Exchange Act reports is recorded, processed, summarized and reported within the time periods specified in the SEC’s rules and forms, and that such information is accumulated and communicated to management, including the chief executive officer and the chief financial officer, as appropriate, to allow timely decisions regarding required disclosure. Based on this evaluation, the chief executive officer and chief financial officer have concluded that the Company’s disclosure controls and procedures are effective.

During the most recent quarter, there were no changes in internal controls over financial reporting that occurred during the period covered by this report that have materially affected, or are reasonably likely to materially affect, these controls of the Company.

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PART II-OTHER INFORMATION

ITEM 1. LEGAL PROCEEDINGS

In July 2006, we filed suit against Neuralstem, Inc. in the Federal District Court for the District of Maryland, alleging that Neuralstem’s activities violate claims in four of the patents we exclusively licensed from NeuroSpheres, specifically U.S. Patent No. 6,294,346 (claiming the use of human neural stem cells for drug screening), U.S. Patent No. 7,101,709 (claiming the use of human neural stem cells for screening biological agents), U.S. Patent No. 5,851,832 (claiming methods for proliferating human neural stem cells), and U.S. Patent No. 6,497,872 (claiming methods for transplanting human neural stem cells). In May 2008, we filed a second patent infringement suit against Neuralstem and its two founders, Karl Johe and Richard Garr. In this suit, which we filed in the Federal District Court for the Northern District of California, we allege that Neuralstem’s activities infringe claims in two patents we exclusively license from NeuroSpheres, specifically U.S. Patent No. 7,361,505 (claiming composition of matter of human neural stem cells derived from any source material) and U.S. Patent No. 7,115,418 (claiming methods for proliferating human neural stem cells). In addition, we allege various state law causes of action against Neuralstem arising out of its repeated derogatory statements to the public about our patent portfolio. Also in May 2008, Neuralstem filed suit against us and NeuroSpheres in the Federal District Court for the District of Maryland seeking a declaratory judgment that the ‘505 and ‘418 patents are either invalid or are not infringed by Neuralstem and that Neuralstem has not violated California state law. In August 2008, the California court transferred our lawsuit against Neuralstem to Maryland for resolution on the merits. In July 2009, the Maryland District Court granted our motion to consolidate these two cases with the litigation we initiated against Neuralstem in 2006. Discovery is ongoing in these cases and we anticipate a trial date in 2013.

In addition to the actions described above, in April 2008, we filed an opposition to Neuralstem’s European Patent No. 0 915 968 (methods of isolating, propagating and differentiating CNS stem cells), because the claimed invention is believed by us to be unpatentable over prior art, including the patents exclusively licensed by us from NeuroSpheres. In December 2010, the European Patent Office ruled that all composition claims in Neuralstem’s ‘968 European patent were invalid and unpatentable over prior art including several of the NeuroSpheres patents licensed to us. Neuralstem has appealed this decision.

ITEM 1A. RISK FACTORS

There have been no material change from the risk factors disclosed in Part I, Item 1A, of our Annual Report on Form 10-K for the fiscal year ended December 31, 2011.

ITEM 2. UNREGISTERED SALES OF EQUITY SECURITIES AND USE OF PROCEEDS

In September 2012, we issued 24,753 shares of restricted common stock under the terms of an agreement with a developer of biological materials in return for certain product rights including an exclusive right of first offer to commercialize the developer’s products as may be developed on or before April 18, 2017.

ITEM 3. DEFAULTS UPON SENIOR SECURITIES

None.

ITEM 4. MINE SAFETY DISCLOSURES

None.

ITEM 5. OTHER INFORMATION

None.

ITEM 6. EXHIBITS

Exhibit 31.1 —	Certification of Martin McGlynn under Section 302 of the Sarbanes-Oxley Act of 2002
Exhibit 31.2 —	Certification of Rodney K. B. Young under Section 302 of the Sarbanes-Oxley Act of 2002
Exhibit 32.1 —	Certification of Martin McGlynn Pursuant to 18 U.S.C. Section 1350, As Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002
Exhibit 32.2 —	Certification of Rodney K. B. Young Pursuant to 18 U.S.C. Section 1350, As Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002
Exhibit 101.1 —	The following materials from the Registrant’s Quarterly Report on Form 10-Q for the quarter ended September 30, 2012 are formatted in XBRL (eXtensible Business Reporting Language): (i) the Condensed Consolidated Balance Sheets, (ii) the Condensed Consolidated Statements of Operations, (iii) the Condensed Consolidated Statements of Comprehensive Income, (iv) the Condensed Consolidated Statements of Cash Flows, and (v) Notes to Condensed Consolidated Financial Statements. (****)

**** Pursuant to Rule 406T of Regulation S-T, the XBRL files on Exhibit 101 hereto are deemed not filed or part of a registration statement or prospectus for purposes of Sections 11 or 12 of the Securities Act of 1933, as amended, are deemed not filed for purposes of Section 18 of the Securities and Exchange Act of 1934, as amended, and otherwise are not subject to liability under those sections.

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SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

	STEMCELLS, INC.
	(name of Registrant)
November 8, 2012
	/s/ Rodney K. B. Young
	Rodney K. B. Young
	Chief Financial Officer

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Exhibit Index

Exhibit 31.1 —	Certification of Martin McGlynn under Section 302 of the Sarbanes-Oxley Act of 2002
Exhibit 31.2 —	Certification of Rodney K. B. Young under Section 302 of the Sarbanes-Oxley Act of 2002
Exhibit 32.1 —	Certification of Martin McGlynn Pursuant to 18 U.S.C. Section 1350, As Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002
Exhibit 32.2 —	Certification of Rodney K. B. Young Pursuant to 18 U.S.C. Section 1350, As Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002
Exhibit 101.1 —	The following materials from the Registrant’s Quarterly Report on Form 10-Q for the quarter ended September 30, 2012 are formatted in XBRL (eXtensible Business Reporting Language): (i) the Condensed Consolidated Balance Sheets, (ii) the Condensed Consolidated Statements of Operations, (iii) the Condensed Consolidated Statements of Comprehensive Income, (iv) the Condensed Consolidated Statements of Cash Flows, and (v) Notes to Condensed Consolidated Financial Statements.(****)

**** Pursuant to Rule 406T of Regulation S-T, the XBRL files on Exhibit 101 hereto are deemed not filed or part of a registration statement or prospectus for purposes of Sections 11 or 12 of the Securities Act of 1933, as amended, are deemed not filed for purposes of Section 18 of the Securities and Exchange Act of 1934, as amended, and otherwise are not subject to liability under those sections.

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EX-31.1

Exhibit 31.1

CERTIFICATION OF CHIEF EXECUTIVE OFFICER

UNDER SECTION 302 OF THE SARBANES-OXLEY ACT

I, Martin McGlynn, certify that:

(1) I have reviewed this quarterly report on Form 10-Q of StemCells, Inc.;

(2) Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

(3) Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this quarterly report;

(4) The registrant’s other certifying officer(s) and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:

(a) designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

(b) designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

(c) evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

(d) disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and

(5) The registrant’s other certifying officer(s) and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):

(a) all significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and

(b) any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial reporting.

Date: November 8, 2012

/s/ Martin McGlynn

Martin McGlynn

President and Chief Executive Officer

EX-31.2

Exhibit 31.2

CERTIFICATION OF CHIEF FINANCIAL OFFICER

UNDER SECTION 302 OF THE SARBANES-OXLEY ACT

I, Rodney K. B. Young, certify that:

(1) I have reviewed this quarterly report on Form 10-Q of StemCells, Inc.;

(2) Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

(3) Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this quarterly report;

(4) The registrant’s other certifying officer(s) and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:

(a) designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

(b) designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

(c) evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

(d) disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and

(5) The registrant’s other certifying officer(s) and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):

(a) all significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and

(b) any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial reporting.

Date: November 8, 2012

/s/ Rodney K. B. Young

Rodney K. B. Young

Chief Financial Officer

EX-32.1

Exhibit 32.1

Certification Pursuant to 18 U.S.C. Section 1350, As Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

In connection with the StemCells, Inc. (the “Company”) quarterly report on Form 10-Q for the period ending September 30, 2012 as filed with the Securities and Exchange Commission on the date hereof (the “Report”), I, Martin McGlynn, President and Chief Executive Officer of the Company, certify pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that, to the best of my knowledge:

(1) The Report fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934, as amended; and

(2) The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.

A signed original of this written statement required by Section 906 has been provided to StemCells, Inc. and will be retained by StemCells, Inc. and furnished to the Securities and Exchange Commission or its staff upon request.

Date November 8, 2012

/s/ Martin McGlynn

Martin McGlynn

President and Chief Executive Officer

EX-32.2

Exhibit 32.2

Certification Pursuant to 18 U.S.C. Section 1350, As Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

In connection with the StemCells, Inc. (the “Company”) quarterly report on Form 10-Q for the period ending September 30, 2012 as filed with the Securities and Exchange Commission on the date hereof (the “Report”), I, Rodney K. B. Young, Chief Financial Officer of the Company, certify pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that, to the best of my knowledge:

(1) The Report fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934, as amended; and

(2) The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company. A signed original of this written statement required by Section 906 has been provided to StemCells, Inc. and will be retained by StemCells, Inc. and furnished to the Securities and Exchange Commission or its staff upon request.

Date: November 8, 2012

/s/ Rodney K. B. Young

Rodney K. B. Young

Chief Financial Officer

XML

Stock-Based Compensation (Details 1) (USD $)	3 Months Ended
	Sep. 30, 2012
Stock option activity
Number of options, Beginning balance	854,958
Number of options, Granted
Weighted-average exercise price per share, Granted
Number of options, Exercised
Weighted-average exercise price, Exercised
Number of options, Cancelled	(380,041)
Weighted-average exercise price, Cancelled	$ 21.93
Number of options, Ending balance	474,917
Weighted-average exercise price per share, Beginning balance	$ 20.26
Weighted-average exercise price per share, Ending balance	$ 18.91

XML

Subsequent Events (Details) (USD $)	1 Months Ended				3 Months Ended	9 Months Ended			9 Months Ended		3 Months Ended		6 Months Ended	9 Months Ended	1 Months Ended			6 Months Ended	9 Months Ended	12 Months Ended
	Oct. 31, 2012	May 02, 2012	Nov. 30, 2009	Nov. 30, 2008	Sep. 30, 2012	Sep. 30, 2012	Sep. 30, 2011	Dec. 31, 2011	Sep. 30, 2012 Subsequent event [Member]	Sep. 30, 2012 Warrant liabilities [Member]	Dec. 31, 2012 Series A Warrants [Member]	Sep. 30, 2012 Series A Warrants [Member]	Jun. 30, 2012 Series A Warrants [Member]	Sep. 30, 2012 Series A Warrants [Member]	May 02, 2012 Series B Warrant [Member]	Nov. 30, 2009 Series B Warrant [Member]	Nov. 30, 2008 Series B Warrant [Member]	Jun. 30, 2012 Series B Warrant [Member]	Sep. 30, 2012 Series B Warrant [Member]	Dec. 31, 2011 Series B Warrant [Member]
Subsequent events (Textual) [Abstract]
Number of warrants exercised						688,171						1,445,400		1,445,400				2,700,000	2,700,000
Gross proceeds		$ 5,300,000			$ 3,375,000	$ 4,153,584			$ 963,000		$ 1,045,660	$ 977,900			$ 5,300,000	$ 12,500,000	$ 20,000,000		$ 3,375,000	$ 10,000,000
Number of shares of common stock												1,445,400	2,700,000	1,445,400		0.40	0.75		2,700,000
Warrants issued														2,700,000					2,700,000
Exercise price of warrant			15.00	23.00		1.40
Common Stock, Shares, Outstanding					35,018,336	35,018,336		22,427,955
Number of shares of common stock	1,691,410									688,171
Sale of stock, price per share	$ 2.20				$ 2.10
Gross proceeds from common stock	$ 3,714,000				$ 16,738,000	$ 16,196,587	$ 10,426,121
The sales agent is paid compensation equal to 3% of gross proceeds	3.00%					3.00%

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Warrant Liability (Details 2) (Series A Warrants [Member])	9 Months Ended
	Sep. 30, 2012
Series A Warrants [Member]
Assumptions used for simulation model
Risk-free interest rate per year	0.50%
Expected volatility per year	95.30%
Expected dividend yield	0.00%
Expected life (years)	4 years 2 months 12 days

XML

Warrant Liability (Details) (USD $)	3 Months Ended		9 Months Ended			9 Months Ended	12 Months Ended
	Sep. 30, 2012	Sep. 30, 2011	Sep. 30, 2012	Sep. 30, 2011	Dec. 31, 2011	Sep. 30, 2012 Warrant agreement 2008 [Member]	Dec. 31, 2011 Warrant agreement 2008 [Member]
Assumptions used for the Black-Scholes option pricing model
Expected life (years)						1 year 7 months 6 days	2 years 4 months 24 days
Risk-free interest rate						0.20%	0.30%
Expected volatility						108.10%	74.10%
Expected dividend yield						0.00%	0.00%
Fair value of warrant liability	$ 14,483,148		$ 14,483,148		$ 6,042,315	$ 129,785	$ 2,224
Change in fair value of warrant liability	$ (11,239,465)	$ 1,697,194	$ (9,974,685)	$ 6,500,377		$ 127,561

XML

Goodwill and Other Intangible Assets (Details) (USD $)	9 Months Ended
	Sep. 30, 2012	Apr. 01, 2009
Purchase price allocated
Net tangible assets	$ 36,000
Estimated life of intangible assets in years	15 years
Total	5,135,000	5,135,000
Customer relationships and developed technology [Member]
Purchase price allocated
Gross Intangible assets	1,310,000
Customer relationships and developed technology [Member] | Maximum [Member]
Purchase price allocated
Estimated life of intangible assets in years	9 years
Customer relationships and developed technology [Member] | Minimum [Member]
Purchase price allocated
Estimated life of intangible assets in years	6 years
In-process research and development [Member]
Purchase price allocated
Gross Intangible assets	1,340,000
Trade name [Member]
Purchase price allocated
Gross Intangible assets	310,000
Estimated life of intangible assets in years	15 years
Goodwill [Member]
Purchase price allocated
Goodwill	$ 2,139,000

XML

Warrant Liability (Tables)

9 Months Ended

Sep. 30, 2012

Warrant Liability [Abstract]

Assumptions used for Black-Scholes option pricing model

	To Calculate Fair Value of Warrant Liability at
	September 30, 2012			December 31, 2011
Expected life (years)		1.6			2.4
Risk-free interest rate		0.2	%		0.3	%
Expected volatility		108.1	%		74.1	%
Expected dividend yield		0	%		0	%

	At September 30, 2012		At December 31, 2011		Change in Fair Value of Warrant Liability
Fair value of liability for warrants issued in 2008	$	129,785	$	2,224	$	127,561

	To Calculate Fair Value of Warrant Liability at
	September 30, 2012			December 31, 2011
Expected life (years)		2.6			3.3
Risk-free interest rate		0.3	%		0.5	%
Expected volatility		90.1	%		90.8	%
Expected dividend yield		0	%		0	%

	At September 30, 2012		At December 31, 2011		Change in Fair Value of Warrant Liability
Fair value of liability for warrants issued in 2009	$	104,703	$	28,971	$	75,732

Assumptions used for simulation model

Risk-free interest rate per year	0.5	%
Expected volatility per year	95.3	%
Expected dividend yield	0	%
Expected life in years	4.2

Summary of changes in fair value of warrant liability

	Series A
	Number of Warrants			Fair value $
Balance at June 30, 2012		10,700,000		$	5,390,018
Less exercised		(1,445,400	)		(728,106	)
Changes in fair value		—			9,586,748
Balance at September 30, 2012		9,254,600		$	14,248,660

Summary of outstanding warrants and fair value of warrant liability

Warrants	Number Outstanding		Exercise Price ($) per share		Fair value
Warrants issued in 2008		1,034,483		23.00	$	129,785
Warrants issued in 2009		400,000		15.00		104,703
Series A Warrants		9,254,660		1.40		14,248,660
Total		10,689,143			$	14,483,148

XML

Warrant Liability (Details 4) (USD $)	Sep. 30, 2012	Jun. 30, 2012
Summary of outstanding warrants and fair value of warrant liability
Number Outstanding	10,689,143
Fair value	$ 14,483,148
Series A Warrants [Member]
Summary of outstanding warrants and fair value of warrant liability
Number Outstanding	9,254,600	10,700,000
Exercise Price per share	$ 1.40
Fair value	14,248,660
Warrants issued in 2008 [Member]
Summary of outstanding warrants and fair value of warrant liability
Number Outstanding	1,034,483
Exercise Price per share	$ 23.00
Fair value	129,785
Warrants issued in 2009 [Member]
Summary of outstanding warrants and fair value of warrant liability
Number Outstanding	400,000
Exercise Price per share	$ 15.00
Fair value	$ 104,703

XML

Stock-Based Compensation (Details 4)	3 Months Ended
	Sep. 30, 2012
Changes in Stock appreciation rights
Number of options, Beginning balance	854,958
Number of options, Granted
Number of SARs, Exercised
Number of options, Ending balance	474,917
Stock Appreciation Rights (SARs) [Member]
Changes in Stock appreciation rights
Number of options, Beginning balance	115,187
Number of options, Granted
Number of SARs, Exercised
Number of SARs, Forfeited and expired	(4,594)
Number of options, Ending balance	110,593
SARs Exercisable, Ending balance	110,593

XML

Goodwill and Other Intangible Assets (Details Textual) (USD $)	3 Months Ended	9 Months Ended
	Sep. 30, 2012	Sep. 30, 2012	Dec. 31, 2011	Apr. 01, 2009
Goodwill and Other Intangible Assets (Textual) [Abstract]
Aggregate purchase price	$ 5,135,000	$ 5,135,000		$ 5,135,000
Impairment amount of intangible asset			655,000
Useful life		15 years
Amortization Expense	$ 66,000

XML

Common Stock (Details) (USD $)	1 Months Ended				3 Months Ended	9 Months Ended		3 Months Ended		6 Months Ended	9 Months Ended	1 Months Ended			6 Months Ended	9 Months Ended	12 Months Ended
	Oct. 31, 2012	May 02, 2012	Nov. 30, 2009	Nov. 30, 2008	Sep. 30, 2012	Sep. 30, 2012	Sep. 30, 2011	Dec. 31, 2012 Series A Warrants [Member]	Sep. 30, 2012 Series A Warrants [Member]	Jun. 30, 2012 Series A Warrants [Member]	Sep. 30, 2012 Series A Warrants [Member]	May 02, 2012 Series B Warrant [Member]	Nov. 30, 2009 Series B Warrant [Member]	Nov. 30, 2008 Series B Warrant [Member]	Jun. 30, 2012 Series B Warrant [Member]	Sep. 30, 2012 Series B Warrant [Member]	Dec. 31, 2011 Series B Warrant [Member]
Common Stock (Textual) [Abstract]
Common stock,sold					7,956,061
Sale of stock, price per share	$ 2.20				$ 2.10
Proceeds from issuance of common stock, net of issuance costs	$ 3,714,000				$ 16,738,000	$ 16,196,587	$ 10,426,121
The sales agent is paid compensation equal to 3% of gross proceeds	3.00%					3.00%
Number of warrants exercised						688,171			1,445,400		1,445,400				2,700,000	2,700,000
Gross proceeds		$ 5,300,000			$ 3,375,000	$ 4,153,584		$ 1,045,660	$ 977,900			$ 5,300,000	$ 12,500,000	$ 20,000,000		$ 3,375,000	$ 10,000,000
Common stock, shares issued									1,445,400	2,700,000	1,445,400		0.40	0.75		2,700,000
Warrants issued											2,700,000					2,700,000
Exercise price of warrant			15.00	23.00		1.40

XML

Warrant Liability (Details 1) (USD $)	3 Months Ended		9 Months Ended			6 Months Ended	9 Months Ended	12 Months Ended
	Sep. 30, 2012	Sep. 30, 2011	Sep. 30, 2012	Sep. 30, 2011	Dec. 31, 2011	Jun. 30, 2012 Warrant agreement 2009 [Member]	Sep. 30, 2012 Warrant agreement 2009 [Member]	Dec. 31, 2011 Warrant agreement 2009 [Member]
Assumptions used for the Black-Scholes option pricing model
Expected life (years)							2 years 7 months 6 days	3 years 3 months 18 days
Risk-free interest rate							0.30%	0.50%
Expected volatility							90.10%	90.80%
Expected dividend yield							0.00%	0.00%
Fair value of warrant liability	$ 14,483,148		$ 14,483,148		$ 6,042,315		$ 104,703	$ 28,971
Change in fair value of warrant liability	$ (11,239,465)	$ 1,697,194	$ (9,974,685)	$ 6,500,377		$ 75,732

XML

Fair Value Measurement

9 Months Ended

Sep. 30, 2012

Fair Value Measurement [Abstract]

Fair Value Measurement

Note 3. Fair Value Measurement

The following tables present our assets and liabilities that are measured at fair value on a recurring basis and are categorized using the fair value hierarchy. The fair value hierarchy has three levels based on the reliability of the inputs used to determine fair value.

Level 1 — Observable inputs that reflect quoted prices (unadjusted) for identical assets or liabilities in active markets.

Level 2 — Directly or indirectly observable inputs other than in Level 1, that include quoted prices for similar assets or liabilities in active markets or quoted prices for identical or similar assets or liabilities in markets that are not active.

Level 3 — Unobservable inputs which are supported by little or no market activity that reflects the reporting entity’s own assumptions about the assumptions that market participants would use in pricing the asset or liability.

The fair value hierarchy also requires us to maximize the use of observable inputs and minimize the use of unobservable inputs when measuring fair value.

Our cash equivalents are classified as Level 1 because they are valued primarily using quoted market prices.

Our bonds payable, marketable debt securities, and liability for warrants issued in our 2008 and 2009 financing, are classified as Level 2 as they are valued using alternative pricing sources and models utilizing market observable inputs.

Our liability for warrants issued in our 2011 financing is classified as Level 3 as the liability is valued using a Monte Carlo simulation model. Some of the significant inputs used to calculate the fair value of warrant liability include our stock price on the valuation date, expected volatility of our common stock as traded on NASDAQ, and risk-free interest rates that are derived from the yield on U.S. Treasury debt securities, all of which are observable from active markets. However, the use of a Monte Carlo simulation model requires the input of additional subjective assumptions including management’s assumptions regarding the likelihood of a re-pricing of these warrants pursuant to anti-dilution provisions and the progress of our R&D programs and its affect on potential future financings.

The following table presents financial assets and liabilities measured at fair value as of September 30, 2012:

	Fair Value Measurement at Report Date Using
	Quoted Prices in Active Markets for Identical Assets (Level 1)		Significant Other Observable Inputs (Level 2)		Unobservable Inputs (Level 3)		As of September 30, 2012
Financial assets:
Cash equivalents:
Money market funds	$	1,170,798	$	—	$	—	$	1,170,798
U.S. Treasury debt obligations		14,260,825		—		—		14,260,825
Marketable securities:
Debt securities		—		6,031,735		—		6,031,735
Total financial assets	$	15,431,623	$	6,031,735	$	—	$	21,463,358
Financial liabilities:
Bond obligation	$	—	$	381,250	$	—	$	381,250
Warrant liabilities		—		234,488		14,248,660		14,483,148
Total financial liabilities	$	—	$	615,738	$	14,248,660	$	14,864,398

Level 2 Reconciliation

The following table presents a roll forward for financial assets and liabilities measured at fair value using significant other observable inputs (Level 2) for 2012.

	Level 2 Beginning Balance 12/31/11 $		Net transfers (to) from Level 1 $		Change included in earnings $		Settled $			Level 2 Ending Balance 09/30/12 $
Marketable debt securities		3,280,591		2,751,144		—		—			6,031,735
Bond obligation		522,500		—		—		(141,250	)		381,250
Warrant liabilities		31,195		—		203,293		—			234,488

Transfers from Level 2 to Level 1 are the net of, (i) maturities of short term marketable debt securities into cash and cash equivalents and (ii) additional purchases of marketable debt securities.

Level 3 Reconciliation

The following table presents a roll forward for liabilities measured at fair value using significant unobservable inputs (Level 3) for 2012.

	Warrant Liabilities
Balance at December 31, 2011	$	6,011,120
Less fair value of warrants exercised		(1,823,907	)
Less fair value of warrants expired		(3,560,063	)
Add fair value of warrants issued		1,714,436
Add change in fair value of warrants		11,907,074
Balance at September 30, 2012	$	14,248,660

XML

Stock-Based Compensation (Details Textual) (USD $)	9 Months Ended		3 Months Ended	9 Months Ended
	Sep. 30, 2012	Dec. 31, 2011	Sep. 30, 2012 Options [Member]	Sep. 30, 2012 Options [Member]	Sep. 30, 2012 Options [Member] Maximum [Member]	Sep. 30, 2012 Restricted Stock [Member]	Sep. 30, 2012 Restricted Stock [Member] Maximum [Member]	Sep. 30, 2012 Restricted Stock [Member] Minimum [Member]	Sep. 30, 2012 Stock Appreciation Rights (SARs) [Member]	Sep. 30, 2012 Stock Appreciation Rights (SARs) [Member] Maximum [Member]	Sep. 30, 2012 Equity incentive plans [Member]
Stock-based compensation (Textual) [Abstract]
Shares authorized	75,000,000	75,000,000									642,266
Total unrecognized compensation expense	$ 2,835,000
Vesting period	1 year 10 months 24 days			4 years	3 years	4 years	3 years	1 year	3 years
Term of years					10 years					10 years
Percentage of vested grant date				25.00%					25.00%
Percentage of vested grant date				75.00%					75.00%
Estimated fair value			$ 140,000
Number of restricted unit vest over next fiscal year	20,000
Number of restricted unit would vest over vesting period	32,000
Exercise price									$ 20.00

XML

Financial Instruments (Details) (USD $)	Sep. 30, 2012	Dec. 31, 2011
Available-for-sale marketable securities
Amortized Cost	$ 21,743,907	$ 16,594,470
Gross Unrealized Gains	516
Gross Unrealized (Losses)		(2,618)
Fair Value	21,744,423	16,591,852
Cash [Member]
Available-for-sale marketable securities
Amortized Cost	281,065	291,093
Gross Unrealized Gains
Fair Value	281,065	291,093
Cash equivalents [Member]
Available-for-sale marketable securities
Amortized Cost	15,431,623	13,020,168
Gross Unrealized Gains
Fair Value	15,431,623	13,020,168
Marketable debt securities, current [Member]
Available-for-sale marketable securities
Amortized Cost	6,031,219	3,283,209
Gross Unrealized Gains	516
Gross Unrealized (Losses)		(2,618)
Fair Value	$ 6,031,735	$ 3,280,591

XML

Summary of Significant Accounting Policies (Details Textual) (USD $)	1 Months Ended		3 Months Ended		9 Months Ended			9 Months Ended	1 Months Ended	9 Months Ended	1 Months Ended	9 Months Ended
	Nov. 30, 2009	Nov. 30, 2008	Sep. 30, 2012	Sep. 30, 2011	Sep. 30, 2012	Sep. 30, 2011	Dec. 31, 2011	Sep. 30, 2012 Maximum [Member]	Dec. 31, 2011 Series A [Member]	Sep. 30, 2012 Series A [Member]	Dec. 31, 2011 Series B [Member]	Sep. 30, 2012 Series B [Member]	Sep. 30, 2012 Reverse stock split [Member]
Summary of significant accounting policies (Textual) [Abstract]
Outstanding shares of common stock			35,018,336		35,018,336		22,427,955						139,000,000
Reduced common stock shares outstanding													13,900,000
Previous number of common shares authorized			250,000,000		250,000,000
Shares authorized			75,000,000		75,000,000		75,000,000						75,000,000
Investments with maturities								90 days or less from the date of purchase
Impairment Charges			$ 0	$ 0	$ 0	$ 0
Term of Warrant		5 years							5 years		90 days
Per share of common stock	$ 15.00	$ 23.00							$ 1.40		$ 1.25
Repurchase of common stock	400,000	1,034,483							8,000,000		8,000,000
Impairment of goodwill					0
Value of patent					0
Accumulated other comprehensive income			$ 169,777		$ 169,777		$ 40,713
Number of Warrants exercised												2,700,000
Number of shares issued on exercise of warrants					2,700,000
Number of warrants issued on exercise of warrants										2,700,000
Number of warrants expired by terms												5,300,000

XML

Wind-Down Expenses (Details) (USD $)	3 Months Ended			9 Months Ended		12 Months Ended
	Sep. 30, 2012	Jun. 30, 2012	Mar. 31, 2012	Sep. 30, 2012	Sep. 30, 2011	Dec. 31, 2011	Dec. 31, 2010
Summary of changes to our wind-down reserve
Accrued wind-down reserve at beginning of period		$ 1,148,000	$ 1,418,000			$ 1,683,000	$ 2,644,000
Less actual expenses recorded against estimated reserve during the period	(284,000)	(280,000)	(300,000)	(864,000)		(1,248,000)
Additional expense recorded to revise estimated reserve at period-end	155,000	10,000	35,000	200,000		287,000
Revised reserve at period-end	1,019,000	1,148,000	1,418,000	1,019,000		1,683,000
Add deferred rent at period-end	299,000	350,000	401,000	(69,997)	(1,034,088)	452,000
Total accrued wind-down expenses at period-end (current and non-current)	1,318,000	1,498,000	1,819,000	1,318,000		2,135,000
Accrued wind-down expenses, current	1,318,000	1,498,000	1,428,000	1,318,000		1,361,000
Accrued wind-down expenses, non-current			$ 391,000			$ 774,000

XML

Fair Value Measurement (Details) (Fair Value, Measurements [Member], USD $)	Sep. 30, 2012
Financial assets
Total financial assets	$ 21,463,358
Financial liabilities:
Total financial liabilities	14,864,398
Bond obligation [Member]
Financial liabilities:
Total financial liabilities	381,250
Warrant liabilities [Member]
Financial liabilities:
Total financial liabilities	14,483,148
Money market funds [Member] | Cash equivalents [Member]
Financial assets
Total financial assets	1,170,798
U.S. Treasury debt obligations [Member] | Cash equivalents [Member]
Financial assets
Total financial assets	14,260,825
Debt securities [Member] | Marketable securities [Member]
Financial assets
Total financial assets	6,031,735
Quoted Prices in Active Markets for Identical Assets (Level 1) [Member]
Financial assets
Total financial assets	15,431,623
Quoted Prices in Active Markets for Identical Assets (Level 1) [Member] | Money market funds [Member] | Cash equivalents [Member]
Financial assets
Total financial assets	1,170,798
Quoted Prices in Active Markets for Identical Assets (Level 1) [Member] | U.S. Treasury debt obligations [Member] | Cash equivalents [Member]
Financial assets
Total financial assets	14,260,825
Significant Other Observable Inputs (Level 2) [Member]
Financial assets
Total financial assets	6,031,735
Financial liabilities:
Total financial liabilities	615,738
Significant Other Observable Inputs (Level 2) [Member] | Bond obligation [Member]
Financial liabilities:
Total financial liabilities	381,250
Significant Other Observable Inputs (Level 2) [Member] | Warrant liabilities [Member]
Financial liabilities:
Total financial liabilities	234,488
Significant Other Observable Inputs (Level 2) [Member] | Debt securities [Member] | Marketable securities [Member]
Financial assets
Total financial assets	6,031,735
Unobservable Inputs (Level 3) [Member]
Financial liabilities:
Total financial liabilities	14,248,660
Unobservable Inputs (Level 3) [Member] | Warrant liabilities [Member]
Financial liabilities:
Total financial liabilities	$ 14,248,660

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Fair Value Measurement (Details 1) (USD $)	9 Months Ended
	Sep. 30, 2012	Dec. 31, 2011
Fair Value, Measurements [Member]
Roll forward for financial assets and liabilities measured at fair value using significant other observable inputs (Level 2)
Investments, Fair Value Disclosure	$ 21,463,358
Marketable debt securities, ending Balance	21,463,358
Fair Value Measurement With Unobservable inputs reconciliation recurring basis asset transfers into level 1	2,751,144
Liabilities Measured at Fair Value, ending balance	14,864,398
Marketable debt securities [Member]
Roll forward for financial assets and liabilities measured at fair value using significant other observable inputs (Level 2)
Investments, Fair Value Disclosure	6,031,735	3,280,591
Marketable debt securities, ending Balance	6,031,735	3,280,591
Bond obligation [Member]
Roll forward for financial assets and liabilities measured at fair value using significant other observable inputs (Level 2)
Financial liabilities change settled in earning fair value disclosure	(141,250)
Liabilities Measured at Fair Value, ending balance	381,250	522,500
Warrant liabilities [Member]
Roll forward for financial assets and liabilities measured at fair value using significant other observable inputs (Level 2)
Financial liabilities change included in earning fair value disclosure	203,293
Liabilities Measured at Fair Value, ending balance	$ 234,488	$ 31,195

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Financial Instruments

9 Months Ended

Sep. 30, 2012

Financial Instruments [Abstract]

Financial Instruments

Note 2. Financial Instruments

The following table summarizes the fair value of our cash, cash equivalents and available-for-sale marketable securities held in our current investment portfolio:

	Amortized Cost		Gross Unrealized Gains		Gross Unrealized (Losses)			Fair Value
September 30, 2012
Cash	$	281,065	$	—	$	—		$	281,065
Cash equivalents		15,431,623		—		—			15,431,623
Marketable debt securities, current		6,031,219		516		—			6,031,735
Total cash, cash equivalents, and marketable securities	$	21,743,907	$	516	$	—		$	21,744,423
December 31, 2011
Cash	$	291,093	$	—	$	—		$	291,093
Cash equivalents		13,020,168		—		—			13,020,168
Marketable debt securities, current		3,283,209		—		(2,618	)		3,280,591
Total cash, cash equivalents, and marketable securities	$	16,594,470	$	—	$	(2,618	)	$	16,591,852

Gross unrealized gains and losses on cash equivalents were not significant at September 30, 2012 and December 31, 2011. At September 30, 2012, our investment in money market accounts are composed primarily of U.S. Treasury debt securities, which are classified as cash equivalents in our Consolidated Balance Sheet due to their short maturities. Our investment in short-term marketable debt securities are composed primarily of commercial paper and corporate debt securities.

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Fair Value Measurement (Details 2) (Warrant liabilities [Member], USD $)	9 Months Ended
	Sep. 30, 2012
Warrant liabilities [Member]
Roll forward for liabilities measured at fair value using significant unobservable inputs (Level 3)
Balance at December 31, 2011	$ 6,011,120
Less fair value of warrants exercised	(1,823,907)
Less fair value of warrants expired	(3,560,063)
Add fair value of warrants issued	1,714,436
Add change in fair value of warrants	11,907,074
Balance at September 30, 2012	$ 14,248,660

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Stock-Based Compensation (Details 2) (USD $)	3 Months Ended
	Sep. 30, 2012
Summary of changes in unvested options
Weighted-average exercise price per share, Beginning balance	$ 20.26
Weighted-average exercise price per share, Granted
Weighted-average exercise price per share, Ending balance	$ 18.91
Unvested stock options [Member]
Summary of changes in unvested options
Number of options, Beginning balance	103,993
Number of options, Granted
Number of options, Vested	(14,466)
Number of options, Cancelled	(11,778)
Number of options, Ending balance	77,749
Weighted-average exercise price per share, Beginning balance	$ 11.54
Weighted-average exercise price per share, Granted
Weighted-average exercise price per share, Vested	$ 12.04
Weighted-average exercise price per share, Cancelled	$ 14.29
Weighted-average exercise price per share, Ending balance	$ 11.04
Weighted-average grant date fair value per option, Beginning balance	$ 9.28
Weighted-Average Grant Date Fair Value per option, Granted
Weighted-Average Grant Date Fair Value per option, Vested	$ 9.71
Weighted-Average Grant Date Fair Value per option, Cancelled	$ 11.83
Weighted-average grant date fair Value per option, Ending balance	$ 8.82

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California Institute for Regenerative Medicine Funding Program (Details) (USD $) In Millions, unless otherwise specified	9 Months Ended
	Sep. 30, 2012	Jul. 31, 2012
Spinal Cord Injury [Member]
California institute for regenerative medicine funding program
Approval of Fund by California Institute for Regenerative Medicine (CIRM)		$ 20
Approval of Fund by California Institute for Regenerative Medicine (CIRM) maximum period	4 years
Alzheimer's disease [Member]
California institute for regenerative medicine funding program
Approval of Fund by California Institute for Regenerative Medicine (CIRM)	20
Approval of Fund by California Institute for Regenerative Medicine (CIRM) maximum period	4 years

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Condensed Consolidated Balance Sheets (Unaudited) (USD $)	Sep. 30, 2012	Dec. 31, 2011
Current assets:
Cash and cash equivalents	$ 15,712,688	$ 13,311,261
Marketable securities, current	6,031,735	3,280,591
Trade receivables	99,479	54,527
Other receivables	220,462	213,500
Prepaid assets	388,292	506,464
Other assets, current	791,454	22,063
Total current assets	23,244,110	17,388,406
Property, plant and equipment, net	1,535,590	2,054,563
Other assets, non-current	1,033,206	1,856,057
Goodwill	1,967,570	1,895,000
Other intangible assets, net	1,876,976	2,011,473
Total assets	29,657,452	25,205,499
Current liabilities:
Accounts payable	960,501	1,066,495
Accrued expenses and other current liabilities	1,510,037	2,970,251
Accrued wind-down expenses, current	1,317,676	1,360,766
Deferred revenue, current	55,955	43,910
Capital lease obligation, current	6,765	17,979
Deferred rent, current		2,603
Bonds payable, current	202,500	191,250
Total current liabilities	4,053,434	5,653,254
Bonds payable, non-current	178,750	331,250
Capital lease obligations, non-current	14,415
Fair value of warrant liability	14,483,148	6,042,315
Deposits and other long-term liabilities	246,439	281,807
Accrued wind-down expenses, non-current		774,020
Deferred rent, non-current	1,373,767	1,301,167
Deferred revenue, non-current	83,942	96,562
Total liabilities	20,433,895	14,480,375
Commitments and contingencies (Note 7)
Stockholders' equity:
Common stock, $0.01 par value; 75,000,000 shares authorized; issued and outstanding 35,018,336 at September 30, 2012 and 22,427,955 at December 31, 2011	1,598,679	1,472,776
Additional paid-in capital	365,787,830	341,811,657
Accumulated deficit	(358,332,729)	(332,600,022)
Accumulated other comprehensive income	169,777	40,713
Total stockholders' equity	9,223,557	10,725,124
Total liabilities and stockholders' equity	$ 29,657,452	$ 25,205,499

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Commitments and Contingencies (Details)	9 Months Ended		1 Months Ended	9 Months Ended	1 Months Ended			9 Months Ended		1 Months Ended	9 Months Ended
	Sep. 30, 2012 USD ($)	Dec. 31, 2011 USD ($)	Sep. 30, 2010 Caliper Life Sciences [Member] USD ($) sqft	Sep. 30, 2012 Caliper Life Sciences [Member]	Dec. 31, 2011 BMR-Gateway Boulevard LLC [Member] USD ($)	Dec. 31, 2010 BMR-Gateway Boulevard LLC [Member] USD ($) sqft	Sep. 30, 2012 BMR-Gateway Boulevard LLC [Member] USD ($) sqft	Sep. 30, 2012 Scientific and Administrative Facility [Member] USD ($)	Dec. 31, 2011 Scientific and Administrative Facility [Member] USD ($)	Jan. 31, 2011 Stem Cell Sciences UK [Member] GBP (£) sqft	Sep. 30, 2012 Stem Cell Sciences UK [Member] USD ($)
Commitments and Contingencies (Textual) [Abstract]
Area of facility			13,200			43,000
Term of lease			2 years		11 years 6 months			15 years
Rent over term of lease			$ 1,081,000			$ 17,869,000
Deferred rent		2,603			1,301,000		1,374,000	299,000	452,000
Additional area of facility							30,000
Area of leased space										5,000
Area of lease reduced										1,900
Rental payments										61,000
Annual payments											50,000
Useful life	15 years										14 years
Litigation costs											700,000
Royalty payments											650,000
Operating lease payments								1,172,000
Cash outlay net of subtenant rent								1,450,000
Lease term expires				Sep. 30, 2013				Jun. 30, 2013
Receipt of sub-tenant income								412,000
Commitments and Contingencies (Additional Textual) [Abstract]
Proceeds from the issuance of industrial revenue bonds	5,000,000
Period of maturity	Aug. 01, 2014
Interest rate for remaining bond series	9.50%
Outstanding principal	381,000	523,000
Operating expenses	$ 690,000

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Condensed Consolidated Statements of Cash Flows (Unaudited) (USD $)	9 Months Ended
	Sep. 30, 2012		Sep. 30, 2011
Cash flows from operating activities:
Net loss	$ (25,732,707)		$ (14,116,780)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	759,527		917,147
Stock-based compensation	2,227,145		2,636,445
Gain on sale of marketable securities			(83,750)
Loss on disposal of fixed assets			32,145
Change in fair value of warrant liability	9,974,685		(6,500,377)
Changes in operating assets and liabilities:
Other receivables	19,432		252
Trade receivables	(40,584)		(281,709)
Prepaid and other current assets	170,667		465,514
Other assets, non-current	32,926		18,830
Accounts payable and accrued expenses	(1,613,123)		(142,120)
Accrued wind-down expenses	(817,110)		(820,708)
Deferred revenue	(665)		(4,541)
Deferred rent	69,997		1,034,088
Net cash used in operating activities	(14,949,810)		(16,845,564)
Cash flows from investing activities:
Purchase of marketable securities	(8,109,933)		(10,223,957)
Proceeds from the sale and maturity of marketable securities	5,362,000		5,134,206
Purchases of property, plant and equipment	(19,729)		(330,740)
Proceeds from sale of property, plant and equipment			42,427
Net cash used in investing activities	(2,767,662)		(5,378,064)
Cash flows from financing activities:
Proceeds from issuance of common stock, net of issuance costs	16,196,587		10,426,121
Proceeds from the exercise of stock options			2,386
Proceeds from the exercise of warrants, net of issuance costs	4,153,584
Payments related to net share issuance of stock based awards	(59,090)		(396,201)
Repayment of capital lease obligations	(18,521)		(50,246)
Repayment of bonds payable	(141,250)		(130,000)
Net cash provided by financing activities	20,131,310		9,852,060
Increase (decrease) in cash and cash equivalents	2,413,838		(12,371,565)
Effects of foreign exchange rate changes on cash	(12,411)		(42,182)
Cash and cash equivalents, beginning of period	13,311,261		19,707,821
Cash and cash equivalents, end of period	15,712,688		7,294,074
Supplemental disclosure of cash flow information:
Interest paid	40,114		56,585
Supplemental schedule of non-cash investing and financing activities:
Stock issued for an option agreement	50,000	[1]
Equipment acquired under a capital lease	$ 21,721	[2]

[1] In September 2012, we issued 24,753 shares of restricted common stock under the terms of an agreement with a developer of biological materials in return for certain product rights including an exclusive right of first offer to commercialize the developer’s products as may be developed on or before April 18, 2017.

[2] Represents the present value of future minimum capital lease payments for equipment leased in the third quarter of 2012.

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Goodwill and Other Intangible Assets (Details 2) (USD $)	Sep. 30, 2012	Dec. 31, 2011
Components of other intangible assets
Other intangible asset, Cost	$ 3,939,612
Other intangible asset, Impairment	(654,961)
Other intangible asset, Accumulated Amortization	(1,722,141)
Finite Lived Intangible Assets Foreign Currency Translation	314,466
Other intangible assets, Net Carrying Amount	1,876,976	2,011,473
Customer relationships and developed technology [Member]
Components of other intangible assets
Other intangible asset, Cost	1,310,000
Other intangible asset, Accumulated Amortization	(647,222)
Finite Lived Intangible Assets Foreign Currency Translation	146,820
Other intangible assets, Net Carrying Amount	809,598
In-process research and development [Member]
Components of other intangible assets
Other intangible asset, Cost	1,340,000
Other intangible asset, Impairment	(654,961)
Other intangible asset, Accumulated Amortization	(270,687)
Finite Lived Intangible Assets Foreign Currency Translation	131,710
Other intangible assets, Net Carrying Amount	546,062
Trade Names [Member]
Components of other intangible assets
Other intangible asset, Cost	310,000
Other intangible asset, Accumulated Amortization	(79,716)
Finite Lived Intangible Assets Foreign Currency Translation	35,936
Other intangible assets, Net Carrying Amount	266,220
Patents [Member]
Components of other intangible assets
Other intangible asset, Cost	979,612
Other intangible asset, Accumulated Amortization	(724,516)
Finite Lived Intangible Assets Foreign Currency Translation
Other intangible assets, Net Carrying Amount	$ 255,096

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Goodwill and Other Intangible Assets (Tables)

9 Months Ended

Sep. 30, 2012

Goodwill and Other Intangible Assets [Abstract]

Purchase price allocated

	Allocated purchase Price		Estimated life of intangible assets in years
Net tangible assets	$	36,000
Intangible assets:
Customer relationships and developed technology		1,310,000		6 to 9
In-process research and development		1,340,000		N/A
Trade name		310,000		15
Goodwill		2,139,000		N/A
Total	$	5,135,000

Changes in goodwill

Balance as of December 31, 2011	$	1,895,000
Foreign currency translation		72,570
Balance as of September 30, 2012	$	1,967,570

Components of other intangible assets

Other Intangible Asset Class	Cost		Impairment			Accumulated Amortization			Foreign Currency Translation		Net Carrying Amount
Customer relationships and developed technology	$	1,310,000	$	—		$	(647,222	)	$	146,820	$	809,598
In-process research and development		1,340,000		(654,961	)		(270,687	)		131,710		546,062
Trade name		310,000		—			(79,716	)		35,936		266,220
Patents		979,612		—			(724,516	)		—		255,096
Total other intangible assets	$	3,939,612	$	(654,961	)	$	(1,722,141	)	$	314,466	$	1,876,976

Expected future annual amortization expense

For the year ending December 31:
2013	$	267,000
2014	$	267,000
2015	$	266,000
2016	$	261,000
2017	$	238,000

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Goodwill and Other Intangible Assets (Details 3) (USD $)	Sep. 30, 2012
Expected future annual amortization expense
2013	$ 267,000
2014	267,000
2015	266,000
2016	261,000
2017	$ 238,000

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Wind-Down Expenses (Tables)

9 Months Ended

Sep. 30, 2012

Wind-Down Expenses [Abstract]

Summary of changes to our wind-down reserve

	January 1 to March 31, 2012			April 1 to June 30, 2012			July 1 to September 30, 2012			January 1 to September 30, 2012			January 1 to December 31, 2011
Accrued wind-down reserve at beginning of period	$	1,683,000		$	1,418,000		$	1,148,000		$	1,683,000		$	2,644,000
Less actual expenses recorded against estimated reserve during the period		(300,000	)		(280,000	)		(284,000	)		(864,000	)		(1,248,000	)
Additional expense recorded to revise estimated reserve at period-end		35,000			10,000			155,000			200,000			287,000
Revised reserve at period-end		1,418,000			1,148,000			1,019,000			1,019,000			1,683,000
Add deferred rent at period-end		401,000			350,000			299,000			299,000			452,000
Total accrued wind-down expenses at period-end (current and non-current)	$	1,819,000		$	1,498,000		$	1,318,000		$	1,318,000		$	2,135,000
Accrued wind-down expenses, current	$	1,428,000		$	1,498,000		$	1,318,000		$	1,318,000		$	1,361,000
Accrued wind-down expenses, non-current		391,000			—			—			—			774,000
Total accrued wind-down expenses	$	1,819,000		$	1,498,000		$	1,318,000		$	1,318,000		$	2,135,000

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Summary of Significant Accounting Policies

9 Months Ended

Sep. 30, 2012

Summary of Significant Accounting Policies [Abstract]

Summary of Significant Accounting Policies

Note 1. Summary of Significant Accounting Policies

Nature of Business

StemCells, Inc., a Delaware corporation, is a biopharmaceutical company that operates in one segment, the research, development, and commercialization of stem cell therapeutics and related technologies.

The accompanying financial data as of September 30, 2012 and for the three and nine months ended September 30, 2012 and 2011 have been prepared by us, without audit, pursuant to the rules and regulations of the Securities and Exchange Commission (SEC). Certain information and footnote disclosures normally included in financial statements prepared in accordance with accounting principles generally accepted in the United States (U.S. GAAP) have been condensed or omitted pursuant to these rules and regulations. The December 31, 2011 condensed consolidated balance sheet was derived from audited financial statements, but does not include all disclosures required by U.S. GAAP. However, we believe that the disclosures are adequate to make the information presented not misleading. These condensed consolidated financial statements should be read in conjunction with the consolidated financial statements and the notes thereto included in our Annual Report on Form 10-K for the fiscal year ended December 31, 2011.

We have incurred significant operating losses since inception. We expect to incur additional operating losses over the foreseeable future. We have very limited liquidity and capital resources and must obtain significant additional capital and other resources in order to provide funding for our product development efforts, the acquisition of technologies, businesses and intellectual property rights, preclinical and clinical testing of our products, pursuit of regulatory approvals, acquisition of capital equipment, laboratory and office facilities, establishment of production capabilities, selling, general and administrative expenses and other working capital requirements. We rely on our cash reserves, proceeds from equity and debt offerings, proceeds from the transfer or sale of intellectual property rights, equipment, facilities or investments, government grants and funding from collaborative arrangements, to fund our operations. If we exhaust our cash reserves and are unable to obtain adequate financing, we may be unable to meet our operating obligations and we may be required to initiate bankruptcy proceedings. The financial statements do not include any adjustments to reflect the possible future effects on the recoverability and classification of assets or the amounts and classification of liabilities that may result from the outcome of this uncertainty.

Reverse Stock Split

We effected a 1-for-10 reverse stock split on July 6, 2011. As a result of the reverse stock split, the outstanding shares of common stock issued and outstanding were reduced from approximately 139 million to 13.9 million. Concurrent with the reverse stock split, we reduced the authorized number of common shares from 250 million to 75 million. The reverse stock split proportionately reduced all issued and outstanding shares of our common stock, as well as common stock underlying stock options, warrants and other common stock based equity grants outstanding immediately prior to the effectiveness of the reverse stock split. The exercise price on outstanding equity-based grants was proportionately increased, and the number of shares available under our equity-based plans was proportionately reduced. Share and per share data (except par value) for the periods presented reflect the effects of this reverse stock split. References to numbers of shares of common stock and per share data in the accompanying financial statements and notes thereto have been adjusted to reflect the reverse stock split on a retroactive basis.

Principles of Consolidation

The condensed consolidated financial statements include the accounts of StemCells, Inc., and our wholly-owned subsidiaries, including StemCells California, Inc., Stem Cell Sciences Holdings Ltd, and Stem Cell Sciences (UK) Ltd. All significant intercompany accounts and transactions have been eliminated.

Use of Estimates

The preparation of financial statements in conformity with U.S. GAAP requires management to make judgments, assumptions and estimates that affect the amounts reported in our condensed consolidated financial statements and accompanying notes. Actual results could differ materially from these estimates.

Significant estimates include the following:

• the grant date fair value of stock-based awards recognized as compensation expense (see Note 5, “Stock-Based Compensation”);

• accrued wind-down expenses (see Note 6, “Wind-Down Expenses”);

• the fair value of warrants recorded as a liability (see Note 8, “Warrant Liability”); and

• the fair value of goodwill and other intangible assets (see Note 4, “Goodwill and Other Intangible Assets”).

Financial Instruments

Cash and Cash Equivalents

Cash equivalents are money market accounts, money market funds and investments with maturities of 90 days or less from the date of purchase.

Marketable Securities

Our existing marketable securities are designated as available-for-sale securities. These securities are carried at fair value (see Note 2, “Financial Instruments”), with the unrealized gains and losses reported as a component of stockholders’ equity. Management determines the appropriate designation of its investments (current or non-current) in marketable securities at the time of purchase and reevaluates such designation as of each balance sheet date. The cost of securities sold is based upon the specific identification method.

If the estimated fair value of a security is below its carrying value, we evaluate whether we have the intent and ability to retain our investment for a period of time sufficient to allow for any anticipated recovery to the cost of the investment, and whether evidence indicating that the cost of the investment is recoverable within a reasonable period of time outweighs evidence to the contrary. Other-than-temporary declines in estimated fair value of all marketable securities are charged to “Other income (expense), net” in the accompanying condensed consolidated statements of operations. No such impairment was recognized during the three and nine months ended September 30, 2012 or 2011.

Trade and Other Receivables

Our receivables generally consist of interest income on our financial instruments, revenue from licensing agreements and grants, revenue from product sales, and rent from our sub-lease tenants.

Warrant Liability

We account for our warrants in accordance with U.S. GAAP which defines how freestanding contracts that are indexed to and potentially settled in a company’s own stock should be measured and classified. Authoritative accounting guidance prescribes that only warrants issued by us under contracts that cannot be net-cash settled, and are both indexed to and settled in our common stock, can be classified as equity. As part of both our November 2008 and November 2009 financings, we issued warrants with five year terms to purchase 1,034,483 and 400,000 shares of our common stock at $23.00 and $15.00 per share, respectively. As part of our December 2011 financing, we issued Series A Warrants with a five year term to purchase 8,000,000 shares at $1.40 per share and Series B Warrants with a ninety trading day term to purchase 8,000,000 units at $1.25 per unit. Each unit underlying the Series B Warrants consisted of one share of our common stock and one Series A Warrant. In the first and second quarter of 2012, an aggregate of 2,700,000 Series B Warrants were exercised. For the exercise of these warrants, we issued 2,700,000 shares of our common stock and 2,700,000 Series A Warrants with an exercise price of $1.40 per share. The remaining 5,300,000 Series B Warrants expired unexercised by their terms on May 2, 2012. As terms of the warrants issued in 2008 and 2009, as well as the Series A and Series B warrants, do not meet the specific conditions for equity classification, we are required to classify the fair value of these warrants as a liability, with subsequent changes in fair value to be recorded as income (loss) due to change in fair value of warrant liability. The fair value of the warrants issued in the 2008 and 2009 financings is determined using the Black-Scholes-Merton (Black-Scholes) option pricing model and the fair value of the Series A and Series B Warrants is determined using a Monte Carlo simulation model (see Note 8, “Warrant Liability”). The fair value is affected by changes in inputs to these models including our stock price, expected stock price volatility, the contractual term, and the risk-free interest rate. The use of a Monte Carlo simulation model requires input of additional assumptions including the progress of our R&D programs and its affect on potential future financings. We will continue to classify the fair value of the warrants as a liability until the warrants are exercised, expire or are amended in a way that would no longer require these warrants to be classified as a liability.

Goodwill and Other Intangible Assets

Goodwill and intangible assets deemed to have indefinite lives are not amortized but are subject to annual impairment tests. If the assumptions and estimates used to allocate the purchase price are not correct, or if business conditions change, purchase price adjustments or future asset impairment charges could be required. We test goodwill for impairment on an annual basis or more frequently if we believe indicators of impairment exist. Impairment evaluations involve management estimates of asset useful lives and future cash flows. Significant management judgment is required in the forecasts of future operating results that are used in the evaluations, and it is possible, even likely, that the plans and estimates used may be incorrect. If our actual results, or the plans and estimates used in future impairment analysis are lower than the original estimates used to assess the recoverability of these assets, we could incur additional impairment charges in a future period. We completed our annual impairment testing during the fourth quarter of 2011, and determined that there was no impairment of goodwill.

Prior to fiscal year 2001, we capitalized certain patent costs, which are being amortized over the estimated life of the patent and would be expensed at the time such patents are deemed to have no continuing value. Since 2001, all patent costs are expensed as incurred. License costs are capitalized and amortized over the estimated life of the related license agreement.

Revenue Recognition

We currently recognize revenue resulting from the licensing and use of our technology and intellectual property, from government grants, from services provided to third parties, and from product sales. Licensing agreements may contain multiple elements, such as upfront fees, payments related to the achievement of particular milestones and royalties. Revenue from upfront fees for licensing agreements that contain multiple elements are generally deferred and recognized on a straight-line basis over the term of the agreement. Fees associated with substantive at risk performance-based milestones are recognized as revenue upon completion of the scientific or regulatory event specified in the agreement, and royalties received are recognized as earned. Revenue from licensing agreements is recognized net of a fixed percentage due to licensors as royalties. Grant revenue from government agencies are funds received to cover specific expenses and are recognized as earned upon either the incurring of reimbursable expenses directly related to the particular research plan or the completion of certain development milestones as defined within the terms of the relevant collaborative agreement or grant. Revenue from services to third parties is recognized when we have provided the agreed upon services. Revenue from product sales are recognized when the product is shipped and the order fulfilled.

Stock-Based Compensation

Compensation expense for stock-based payment awards to employees is based on their grant date fair value as calculated and amortized over their vesting period. See Note 5, “Stock-Based Compensation” for further information.

We use the Black-Scholes model to calculate the fair value of stock-based awards.

Per Share Data

Basic net income or loss per share is computed by dividing net income or loss by the weighted average number of shares of common stock outstanding during the period. Diluted net income or loss per share is computed based on the weighted average number of shares of common stock and other dilutive securities. To the extent these securities are anti-dilutive, they are excluded from the calculation of diluted earnings per share.

The following is a reconciliation of the numerators and denominators of the basic and diluted net income or loss per share computations:

	Three months ended September 30,						Nine months ended September 30,
	2012			2011			2012			2011
Net loss	$	(16,336,790	)	$	(4,334,352	)	$	(25,732,707	)	$	(14,116,780	)
Weighted average shares outstanding used to compute basic and diluted net income or loss per share		30,168,475			14,009,341			25,992,764			13,831,749
Basic and diluted net loss per share	$	(0.54	)	$	(0.31	)	$	(0.99	)	$	(1.02	)

The following outstanding potentially dilutive common stock equivalents were excluded from the computation of diluted net income or loss per share because the effect would have been anti-dilutive as of September 30:

	2012		2011
Options		474,917		895,962
Restricted stock units		1,516,199		338,041
Warrants		10,689,083		1,434,483
Total		12,680,199		2,668,486

Comprehensive Income (Loss)

Comprehensive income (loss) is comprised of net income or loss and other comprehensive income or loss (OCL). OCL includes certain changes in stockholders’ equity that are excluded from net income or loss. Specifically, we include in OCL changes in unrealized gains and losses on our marketable securities and unrealized gains and losses on foreign currency translations. Accumulated other comprehensive income was $169,777, as of September 30, 2012, and $40,713, as of December 31, 2011.

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Condensed Consolidated Balance Sheets (Unaudited) (Parenthetical) (USD $)	Sep. 30, 2012	Dec. 31, 2011
Condensed Consolidated Balance Sheets [Abstract]
Common stock, par value	$ 0.01	$ 0.01
Common stock, shares authorized	75,000,000	75,000,000
Common stock, shares issued	35,018,336	22,427,955
Shares of common stock	35,018,336	22,427,955

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Subsequent Events

9 Months Ended

Sep. 30, 2012

Subsequent Events [Abstract]

Subsequent Events

Note 11. Subsequent Events

Subsequent to the end of the third quarter, 688,171 Series A Warrants were exercised at an exercise price of $1.40 per share. We will receive gross proceeds of approximately $963,000 and issue 688,171 shares of our common stock.

In October 2012, we sold a total of 1,691,410 shares of our common stock at an average price per share of $2.20 for gross proceeds of approximately $3,714,000. The shares were sold under a sales agreement entered into in June 2009 and the sales agent is paid compensation equal to 3% of gross proceeds pursuant to the terms of the agreement. The shares were offered under our shelf registration statement previously filed with, and declared effective by, the SEC.

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Document and Entity Information	9 Months Ended
	Sep. 30, 2012	Oct. 26, 2012
Document and Entity Information [Abstract]
Entity Registrant Name	STEMCELLS INC
Entity Central Index Key	0000883975
Document Type	10-Q
Document Period End Date	Sep. 30, 2012
Amendment Flag	false
Document Fiscal Year Focus	2012
Document Fiscal Period Focus	Q3
Current Fiscal Year End Date	--12-31
Entity Filer Category	Accelerated Filer
Entity Common Stock, Shares Outstanding		37,440,305

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Summary of Significant Accounting Policies (Policies)

9 Months Ended

Sep. 30, 2012

Summary of Significant Accounting Policies [Abstract]

Nature of Business

Nature of Business

StemCells, Inc., a Delaware corporation, is a biopharmaceutical company that operates in one segment, the research, development, and commercialization of stem cell therapeutics and related technologies.

The accompanying financial data as of September 30, 2012 and for the three and nine months ended September 30, 2012 and 2011 have been prepared by us, without audit, pursuant to the rules and regulations of the Securities and Exchange Commission (SEC). Certain information and footnote disclosures normally included in financial statements prepared in accordance with accounting principles generally accepted in the United States (U.S. GAAP) have been condensed or omitted pursuant to these rules and regulations. The December 31, 2011 condensed consolidated balance sheet was derived from audited financial statements, but does not include all disclosures required by U.S. GAAP. However, we believe that the disclosures are adequate to make the information presented not misleading. These condensed consolidated financial statements should be read in conjunction with the consolidated financial statements and the notes thereto included in our Annual Report on Form 10-K for the fiscal year ended December 31, 2011.

We have incurred significant operating losses since inception. We expect to incur additional operating losses over the foreseeable future. We have very limited liquidity and capital resources and must obtain significant additional capital and other resources in order to provide funding for our product development efforts, the acquisition of technologies, businesses and intellectual property rights, preclinical and clinical testing of our products, pursuit of regulatory approvals, acquisition of capital equipment, laboratory and office facilities, establishment of production capabilities, selling, general and administrative expenses and other working capital requirements. We rely on our cash reserves, proceeds from equity and debt offerings, proceeds from the transfer or sale of intellectual property rights, equipment, facilities or investments, government grants and funding from collaborative arrangements, to fund our operations. If we exhaust our cash reserves and are unable to obtain adequate financing, we may be unable to meet our operating obligations and we may be required to initiate bankruptcy proceedings. The financial statements do not include any adjustments to reflect the possible future effects on the recoverability and classification of assets or the amounts and classification of liabilities that may result from the outcome of this uncertainty.

Reverse Stock Split

Reverse Stock Split

We effected a 1-for-10 reverse stock split on July 6, 2011. As a result of the reverse stock split, the outstanding shares of common stock issued and outstanding were reduced from approximately 139 million to 13.9 million. Concurrent with the reverse stock split, we reduced the authorized number of common shares from 250 million to 75 million. The reverse stock split proportionately reduced all issued and outstanding shares of our common stock, as well as common stock underlying stock options, warrants and other common stock based equity grants outstanding immediately prior to the effectiveness of the reverse stock split. The exercise price on outstanding equity-based grants was proportionately increased, and the number of shares available under our equity-based plans was proportionately reduced. Share and per share data (except par value) for the periods presented reflect the effects of this reverse stock split. References to numbers of shares of common stock and per share data in the accompanying financial statements and notes thereto have been adjusted to reflect the reverse stock split on a retroactive basis.

Principles of Consolidation

Principles of Consolidation

The condensed consolidated financial statements include the accounts of StemCells, Inc., and our wholly-owned subsidiaries, including StemCells California, Inc., Stem Cell Sciences Holdings Ltd, and Stem Cell Sciences (UK) Ltd. All significant intercompany accounts and transactions have been eliminated.

Use of Estimates

Use of Estimates

The preparation of financial statements in conformity with U.S. GAAP requires management to make judgments, assumptions and estimates that affect the amounts reported in our condensed consolidated financial statements and accompanying notes. Actual results could differ materially from these estimates.

Significant estimates include the following:

• the grant date fair value of stock-based awards recognized as compensation expense (see Note 5, “Stock-Based Compensation”);

• accrued wind-down expenses (see Note 6, “Wind-Down Expenses”);

• the fair value of warrants recorded as a liability (see Note 8, “Warrant Liability”); and

• the fair value of goodwill and other intangible assets (see Note 4, “Goodwill and Other Intangible Assets”).

Financial Instruments

Financial Instruments

Cash and Cash Equivalents

Cash equivalents are money market accounts, money market funds and investments with maturities of 90 days or less from the date of purchase.

Marketable Securities

Our existing marketable securities are designated as available-for-sale securities. These securities are carried at fair value (see Note 2, “Financial Instruments”), with the unrealized gains and losses reported as a component of stockholders’ equity. Management determines the appropriate designation of its investments (current or non-current) in marketable securities at the time of purchase and reevaluates such designation as of each balance sheet date. The cost of securities sold is based upon the specific identification method.

If the estimated fair value of a security is below its carrying value, we evaluate whether we have the intent and ability to retain our investment for a period of time sufficient to allow for any anticipated recovery to the cost of the investment, and whether evidence indicating that the cost of the investment is recoverable within a reasonable period of time outweighs evidence to the contrary. Other-than-temporary declines in estimated fair value of all marketable securities are charged to “Other income (expense), net” in the accompanying condensed consolidated statements of operations. No such impairment was recognized during the three and nine months ended September 30, 2012 or 2011.

Trade and Other Receivables

Our receivables generally consist of interest income on our financial instruments, revenue from licensing agreements and grants, revenue from product sales, and rent from our sub-lease tenants.

Warrant Liability

We account for our warrants in accordance with U.S. GAAP which defines how freestanding contracts that are indexed to and potentially settled in a company’s own stock should be measured and classified. Authoritative accounting guidance prescribes that only warrants issued by us under contracts that cannot be net-cash settled, and are both indexed to and settled in our common stock, can be classified as equity. As part of both our November 2008 and November 2009 financings, we issued warrants with five year terms to purchase 1,034,483 and 400,000 shares of our common stock at $23.00 and $15.00 per share, respectively. As part of our December 2011 financing, we issued Series A Warrants with a five year term to purchase 8,000,000 shares at $1.40 per share and Series B Warrants with a ninety trading day term to purchase 8,000,000 units at $1.25 per unit. Each unit underlying the Series B Warrants consisted of one share of our common stock and one Series A Warrant. In the first and second quarter of 2012, an aggregate of 2,700,000 Series B Warrants were exercised. For the exercise of these warrants, we issued 2,700,000 shares of our common stock and 2,700,000 Series A Warrants with an exercise price of $1.40 per share. The remaining 5,300,000 Series B Warrants expired unexercised by their terms on May 2, 2012. As terms of the warrants issued in 2008 and 2009, as well as the Series A and Series B warrants, do not meet the specific conditions for equity classification, we are required to classify the fair value of these warrants as a liability, with subsequent changes in fair value to be recorded as income (loss) due to change in fair value of warrant liability. The fair value of the warrants issued in the 2008 and 2009 financings is determined using the Black-Scholes-Merton (Black-Scholes) option pricing model and the fair value of the Series A and Series B Warrants is determined using a Monte Carlo simulation model (see Note 8, “Warrant Liability”). The fair value is affected by changes in inputs to these models including our stock price, expected stock price volatility, the contractual term, and the risk-free interest rate. The use of a Monte Carlo simulation model requires input of additional assumptions including the progress of our R&D programs and its affect on potential future financings. We will continue to classify the fair value of the warrants as a liability until the warrants are exercised, expire or are amended in a way that would no longer require these warrants to be classified as a liability.

Goodwill and Other Intangible Assets

Goodwill and Other Intangible Assets

Goodwill and intangible assets deemed to have indefinite lives are not amortized but are subject to annual impairment tests. If the assumptions and estimates used to allocate the purchase price are not correct, or if business conditions change, purchase price adjustments or future asset impairment charges could be required. We test goodwill for impairment on an annual basis or more frequently if we believe indicators of impairment exist. Impairment evaluations involve management estimates of asset useful lives and future cash flows. Significant management judgment is required in the forecasts of future operating results that are used in the evaluations, and it is possible, even likely, that the plans and estimates used may be incorrect. If our actual results, or the plans and estimates used in future impairment analysis are lower than the original estimates used to assess the recoverability of these assets, we could incur additional impairment charges in a future period. We completed our annual impairment testing during the fourth quarter of 2011, and determined that there was no impairment of goodwill.

Prior to fiscal year 2001, we capitalized certain patent costs, which are being amortized over the estimated life of the patent and would be expensed at the time such patents are deemed to have no continuing value. Since 2001, all patent costs are expensed as incurred. License costs are capitalized and amortized over the estimated life of the related license agreement.

Revenue Recognition

Revenue Recognition

We currently recognize revenue resulting from the licensing and use of our technology and intellectual property, from government grants, from services provided to third parties, and from product sales. Licensing agreements may contain multiple elements, such as upfront fees, payments related to the achievement of particular milestones and royalties. Revenue from upfront fees for licensing agreements that contain multiple elements are generally deferred and recognized on a straight-line basis over the term of the agreement. Fees associated with substantive at risk performance-based milestones are recognized as revenue upon completion of the scientific or regulatory event specified in the agreement, and royalties received are recognized as earned. Revenue from licensing agreements is recognized net of a fixed percentage due to licensors as royalties. Grant revenue from government agencies are funds received to cover specific expenses and are recognized as earned upon either the incurring of reimbursable expenses directly related to the particular research plan or the completion of certain development milestones as defined within the terms of the relevant collaborative agreement or grant. Revenue from services to third parties is recognized when we have provided the agreed upon services. Revenue from product sales are recognized when the product is shipped and the order fulfilled.

Stock-Based Compensation

Stock-Based Compensation

Compensation expense for stock-based payment awards to employees is based on their grant date fair value as calculated and amortized over their vesting period. See Note 5, “Stock-Based Compensation” for further information.

We use the Black-Scholes model to calculate the fair value of stock-based awards.

Per Share Data

Per Share Data

Basic net income or loss per share is computed by dividing net income or loss by the weighted average number of shares of common stock outstanding during the period. Diluted net income or loss per share is computed based on the weighted average number of shares of common stock and other dilutive securities. To the extent these securities are anti-dilutive, they are excluded from the calculation of diluted earnings per share.

Comprehensive Income (Loss)

Comprehensive Income (Loss)

Comprehensive income (loss) is comprised of net income or loss and other comprehensive income or loss (OCL). OCL includes certain changes in stockholders’ equity that are excluded from net income or loss. Specifically, we include in OCL changes in unrealized gains and losses on our marketable securities and unrealized gains and losses on foreign currency translations. Accumulated other comprehensive income was $169,777, as of September 30, 2012, and $40,713, as of December 31, 2011.

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Condensed Consolidated Statements of Operations (Unaudited) (USD $)	3 Months Ended		9 Months Ended
	Sep. 30, 2012	Sep. 30, 2011	Sep. 30, 2012	Sep. 30, 2011
Revenue:
Revenue from licensing agreements, grants and other	$ 60,739	$ 41,265	$ 471,501	$ 162,614
Revenue from product sales	203,256	182,321	685,364	516,536
Total revenue	263,995	223,586	1,156,865	679,150
Cost of product sales	71,891	60,501	208,127	167,390
Gross profit	192,104	163,085	948,738	511,760
Operating expenses:
Research and development	3,478,142	4,524,334	11,165,599	15,103,845
Selling, general and administrative	1,636,438	1,733,229	5,336,105	5,912,220
Wind-down expenses	154,742	68,694	199,799	258,749
Total operating expenses	5,269,322	6,326,257	16,701,503	21,274,814
Loss from operations	(5,077,218)	(6,163,172)	(15,752,765)	(20,763,054)
Other income (expense):
Change in fair value of warrant liability	(11,239,465)	1,697,194	(9,974,685)	6,500,377
Realized gain on sale of marketable securities				83,750
Interest income	2,372	3,514	9,393	11,332
Interest expense	(11,392)	(16,585)	(40,014)	(56,585)
Other income (expense), net	(11,087)	144,697	25,364	107,400
Total other income (expense), net	(11,259,572)	1,828,820	(9,979,942)	6,646,274
Net loss	$ (16,336,790)	$ (4,334,352)	$ (25,732,707)	$ (14,116,780)
Basic and diluted net loss per share	$ (0.54)	$ (0.31)	$ (0.99)	$ (1.02)
Weighted average number of common shares outstanding, basic and diluted	30,168,475	14,009,341	25,992,764	13,831,749

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Wind-Down Expenses

9 Months Ended

Sep. 30, 2012

Wind-Down Expenses [Abstract]

Wind-Down Expenses

Note 6. Wind-Down Expenses

Rhode Island

In October 1999, we relocated to California from Rhode Island and established a wind down reserve for the estimated lease payments and operating costs of our scientific and administrative facility in Rhode Island. Even though we intend to dispose of the facility at the earliest possible time, we cannot determine with certainty a fixed date by which such disposal will occur. In light of this uncertainty, we periodically re-evaluate and adjust the reserve. We consider various factors such as our lease payments through to the end of the lease, operating expenses, the current real estate market in Rhode Island, and estimated subtenant income based on actual and projected occupancy.

The summary of the changes to our wind-down reserve related to this facility for 2012 and 2011 were as follows:

	January 1 to March 31, 2012			April 1 to June 30, 2012			July 1 to September 30, 2012			January 1 to September 30, 2012			January 1 to December 31, 2011
Accrued wind-down reserve at beginning of period	$	1,683,000		$	1,418,000		$	1,148,000		$	1,683,000		$	2,644,000
Less actual expenses recorded against estimated reserve during the period		(300,000	)		(280,000	)		(284,000	)		(864,000	)		(1,248,000	)
Additional expense recorded to revise estimated reserve at period-end		35,000			10,000			155,000			200,000			287,000
Revised reserve at period-end		1,418,000			1,148,000			1,019,000			1,019,000			1,683,000
Add deferred rent at period-end		401,000			350,000			299,000			299,000			452,000
Total accrued wind-down expenses at period-end (current and non-current)	$	1,819,000		$	1,498,000		$	1,318,000		$	1,318,000		$	2,135,000
Accrued wind-down expenses, current	$	1,428,000		$	1,498,000		$	1,318,000		$	1,318,000		$	1,361,000
Accrued wind-down expenses, non-current		391,000			—			—			—			774,000
Total accrued wind-down expenses	$	1,819,000		$	1,498,000		$	1,318,000		$	1,318,000		$	2,135,000

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Stock-Based Compensation

9 Months Ended

Sep. 30, 2012

Stock-Based Compensation [Abstract]

Stock-Based Compensation

Note 5. Stock-Based Compensation

We currently grant stock-based awards under two equity incentive plans. As of September 30, 2012, we had 642,266 shares authorized to be granted under the two plans. Under these plans we may grant various types of equity awards to our employees, directors and consultants, at prices determined by our Board of Directors, including incentive stock options, nonqualified stock options, stock appreciation rights, restricted stock, restricted stock units, and performance-based shares. Incentive stock options may only be granted to employees under these plans with a grant price not less than the fair market value of the stock on the date of grant. We also use these plans to grant shares to employees for the employer match of employee 401(k) plan contributions.

Our stock-based compensation expense for the three and nine months ended September 30 was as follows:

	Three months ended September 30,						Nine months ended September 30,
	2012			2011			2012			2011
Research and development expense	$	314,393		$	343,845		$	966,570		$	1,304,846
Selling, general and administrative expense		452,760			320,539			1,260,574			1,308,265
Total employee stock-based compensation	$	767,153		$	664,384		$	2,227,144		$	2,613,111
Effect on basic and diluted net loss per share	$	(0.03	)	$	(0.05	)	$	(0.09	)	$	(0.19	)

As of September 30, 2012, we had approximately $2,835,000 of total unrecognized compensation expense related to unvested awards of stock options and restricted stock units granted under our various equity incentive plans that we expect to recognize over a weighted-average vesting period of 1.9 years.

Stock Options

Generally, stock options granted to employees have a maximum term of ten years, and vest over a four year period from the date of grant; 25% vest at the end of one year, and 75% vest monthly over the remaining three-year service period. We may grant options with different vesting terms from time to time. Upon employee termination of service, any unexercised vested option will be forfeited three months following termination or the expiration of the option, whichever is earlier. Unvested options are forfeited on termination.

A summary of our stock option activity for the three months ended September 30, 2012 is as follows:

	Number of options			Weighted-average exercise price ($) per share
Balance at June 30, 2012		854,958			20.26
Granted		—			—
Exercised		—			—
Cancelled		(380,041	)		21.93
Outstanding options at September 30, 2012		474,917			18.91

A summary of changes in unvested options for the three months ended September 30, 2012 is as follows:

	Number of options			Weighted-average exercise price ($) per share		Weighted-average grant date fair value ($) per option
Unvested options at June 30, 2012		103,993			11.54		9.28
Granted		—			—		—
Vested		(14,466	)		12.04		9.71
Cancelled		(11,778	)		14.29		11.83
Unvested options at September 30, 2012		77,749			11.04		8.82

The estimated fair value of options vested was approximately $140,000 in the three months ended September 30, 2012.

Restricted Stock Units

We have granted restricted stock units (RSUs) to certain employees and members of the Board of Directors which entitle the holders to receive shares of our common stock upon vesting of the RSUs. The fair value of restricted stock units granted is based upon the market price of the underlying common stock as if it were vested and issued on the date of grant.

A summary of changes in unvested restricted stock units for the three months ended September 30, 2012 is as follows:

	Number of RSUs			Weighted-average grant date fair value ($) per RSU
Unvested restricted stock units at June 30, 2012		1,467,533			2.12
Granted(1)		52,000			2.15
Vested		(3,333	)		12.59
Cancelled		—			—
Balance unvested at September 30, 2012		1,516,200			2.10

(1) 20,000 of these restricted stock units vest and convert into shares of our common stock after one year from the date of grant. 32,000 of these restricted stock units will vest and convert into shares of our common stock over a four year period from the date of grant; one-fourth of the award will vest on each grant date anniversary following the grant.

Stock Appreciation Rights

In July 2006, we granted cash-settled Stock Appreciation Rights (SARs) to certain employees that give the holder the right, upon exercise, to the difference between the price per share of our common stock at the time of exercise and the exercise price of the SARs.

The SARs have a maximum term of ten years with an exercise price of $20.00, which is equal to the market price of our common stock at the date of grant. The SARs vest 25% on the first anniversary of the grant date and 75% vest monthly over the remaining three-year service period. All of the outstanding SARs as of September 30, 2012 are fully vested. Compensation expense is based on the fair value of SARs which is calculated using the Black-Scholes option pricing model.

The stock-based compensation expense and liability are re-measured at each reporting date through the earlier of date of settlement or forfeiture of the SARs.

A summary of the changes in SARs for the three months ended September 30, 2012 is as follows:

	Number of SARs
Outstanding at June 30, 2012		115,187
Granted		—
Exercised		—
Forfeited and expired		(4,594	)
Outstanding SARs at September 30, 2012		110,593
SARs exercisable at September 30, 2012		110,593

For the three months ended September 30, 2012 and 2011, the re-measured liability and expense for the respective periods related to the SARs were not significant.

The compensation expense related to the SARs recognized for the three months ended September 30, 2012 may not be representative of compensation expense for future periods and its resulting effect on net loss and net loss per share attributable to common stockholders, due to changes in the fair value calculation which is dependent on the stock price, volatility, interest and forfeiture rates, additional grants and subsequent periods of vesting. We will continue to recognize compensation cost each period, which will be the change in fair value from the previous period through the earlier date of settlement or forfeiture of the SARs.

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Stock-Based Compensation (Tables)

9 Months Ended

Sep. 30, 2012

Stock-Based Compensation [Abstract]

Stock-based compensation expense

	Three months ended September 30,						Nine months ended September 30,
	2012			2011			2012			2011
Research and development expense	$	314,393		$	343,845		$	966,570		$	1,304,846
Selling, general and administrative expense		452,760			320,539			1,260,574			1,308,265
Total employee stock-based compensation	$	767,153		$	664,384		$	2,227,144		$	2,613,111
Effect on basic and diluted net loss per share	$	(0.03	)	$	(0.05	)	$	(0.09	)	$	(0.19	)

Stock option activity

	Number of options			Weighted-average exercise price ($) per share
Balance at June 30, 2012		854,958			20.26
Granted		—			—
Exercised		—			—
Cancelled		(380,041	)		21.93
Outstanding options at September 30, 2012		474,917			18.91

Summary of changes in unvested options

	Number of options			Weighted-average exercise price ($) per share		Weighted-average grant date fair value ($) per option
Unvested options at June 30, 2012		103,993			11.54		9.28
Granted		—			—		—
Vested		(14,466	)		12.04		9.71
Cancelled		(11,778	)		14.29		11.83
Unvested options at September 30, 2012		77,749			11.04		8.82

Summary of changes in unvested restricted stock units

	Number of RSUs			Weighted-average grant date fair value ($) per RSU
Unvested restricted stock units at June 30, 2012		1,467,533			2.12
Granted(1)		52,000			2.15
Vested		(3,333	)		12.59
Cancelled		—			—
Balance unvested at September 30, 2012		1,516,200			2.10

(1) 20,000 of these restricted stock units vest and convert into shares of our common stock after one year from the date of grant. 32,000 of these restricted stock units will vest and convert into shares of our common stock over a four year period from the date of grant; one-fourth of the award will vest on each grant date anniversary following the grant.

Summary of changes in Stock appreciation rights

	Number of SARs
Outstanding at June 30, 2012		115,187
Granted		—
Exercised		—
Forfeited and expired		(4,594	)
Outstanding SARs at September 30, 2012		110,593
SARs exercisable at September 30, 2012		110,593

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Summary of Significant Accounting Policies (Tables)

9 Months Ended

Sep. 30, 2012

Summary of Significant Accounting Policies [Abstract]

Reconciliation of the numerators and denominators of the basic and diluted earnings per share computations

	Three months ended September 30,						Nine months ended September 30,
	2012			2011			2012			2011
Net loss	$	(16,336,790	)	$	(4,334,352	)	$	(25,732,707	)	$	(14,116,780	)
Weighted average shares outstanding used to compute basic and diluted net income or loss per share		30,168,475			14,009,341			25,992,764			13,831,749
Basic and diluted net loss per share	$	(0.54	)	$	(0.31	)	$	(0.99	)	$	(1.02	)

Outstanding potentially dilutive common stock

	2012		2011
Options		474,917		895,962
Restricted stock units		1,516,199		338,041
Warrants		10,689,083		1,434,483
Total		12,680,199		2,668,486

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Common Stock

9 Months Ended

Sep. 30, 2012

Common Stock [Abstract]

Common Stock

Note 9. Common Stock

In the third quarter of 2012, we sold a total of 7,956,061 shares of our common stock at an average price per share of $2.10 for gross proceeds of approximately $16,738,000. The shares were sold under a sales agreement entered into in June 2009 and the sales agent is paid compensation equal to 3% of gross proceeds pursuant to the terms of the agreement. The shares were offered under our shelf registration statement previously filed with, and declared effective by, the SEC.

In the first and second quarters of 2012, an aggregate of 2,700,000 Series B Warrants were exercised and we received gross proceeds of $3,375,000. The remaining 5,300,000 Series B Warrants expired unexercised by their terms on May 2, 2012. For the exercise of these warrants, we issued 2,700,000 shares of our common stock and 2,700,000 Series A Warrants. The Series A Warrants have an initial exercise price of $1.40 per share and will expire on the fifth anniversary of the closing date of the initial financing transaction in December 2011.

In the third quarter of 2012, an aggregate of 1,445,400 Series A Warrants were exercised. For the exercise of these warrants, we issued 1,445,400 shares of our common stock and received gross proceeds of $977,900 and $1,045,660 in the third and fourth quarters of 2012 respectively.

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Commitments and Contingencies

9 Months Ended

Sep. 30, 2012

Commitments and Contingencies [Abstract]

Commitments and Contingencies

Note 7. Commitments and Contingencies

Leases

Capital Leases

We entered into direct financing transactions with the State of Rhode Island and received proceeds from the issuance of industrial revenue bonds totaling $5,000,000 to finance the construction of our pilot manufacturing facility in Rhode Island. The related lease agreements are structured such that lease payments fully fund all semiannual interest payments and annual principal payments through maturity in August 2014. The interest rate for the remaining bond series is 9.5%. The bond contains certain restrictive covenants which limit, among other things, the payment of cash dividends and the sale of the related assets. The outstanding principal was approximately $381,000 at September 30, 2012 and $523,000 at December 31, 2011.

Operating Leases

We lease various real properties under operating leases that generally require us to pay taxes, insurance, maintenance, and minimum lease payments. Some of our leases have options to renew.

Operating Leases — California

In September 2010, we entered into a two-year sublease agreement with Caliper Life Sciences, Inc., for approximately 13,200 square feet in a facility located in Mountain View, California. In June 2012, the sublease term was extended to September 30, 2013. We will pay approximately $1,081,000 in aggregate as rent over the term of the lease.

In December 2010, we entered into a commercial lease agreement with BMR-Gateway Boulevard LLC (“BMR”), as landlord, for approximately 43,000 square feet of office and research space at BMR’s Pacific Research Center in Newark, California. The initial term of the lease is approximately eleven and one-half years, and we relocated our corporate headquarters and core research activities from a facility located at the Stanford Research Park in Palo Alto, California, to this facility in July 2011. The lease for the Palo Alto facility expired on August 31, 2011. We will pay approximately $17,869,000 in aggregate as rent over the term of the lease, which we recognize as operating lease expense on a straight-line basis. Deferred rent was approximately $1,374,000 as of September 30, 2012, and approximately $1,301,000 as of December 31, 2011. We constructed laboratories, offices and related infrastructure within the leased space during the first several months of the lease. As part of the lease, BMR has agreed to provide various financial allowances so that we can build initial and future laboratories, offices and other improvements, subject to customary terms and conditions relating to landlord-funded tenant improvements. As part of the lease, we have, until January 2013, an option to lease up to an additional 30,000 square feet in the building.

Operating Leases — Rhode Island

We entered into a fifteen-year lease agreement for a scientific and administrative facility (SAF) in Rhode Island in connection with a sale and leaseback arrangement in 1997. The lease term expires June 30, 2013 and includes escalating rent payments which we recognize on a straight-line basis. Deferred rent expense for this facility was approximately $299,000 at September 30, 2012 and $452,000 at December 31, 2011, and is included as part of the wind-down accrual on the accompanying condensed consolidated balance sheets. For the year 2012, we expect to pay approximately $1,172,000 in operating lease payments and estimated operating expenses of approximately $690,000, before receipt of sub-tenant income and we expect to receive, in aggregate, approximately $412,000 in sub-tenant rent and operating expenses. As a result of the above transactions, our estimated cash outlay net of sub-tenant rent for the SAF will be approximately $1,450,000 for 2012.

Operating Leases — United Kingdom

In January 2011, we amended the existing lease agreements of our wholly-owned subsidiary, Stem Cell Sciences (U.K.) Ltd, effectively reducing our leased space from approximately 5,000 square feet to approximately 1,900 square feet of office and lab space. The lease by its terms was extended to September 30, 2013. We expect to pay approximately 61,000 GBP as rental payments for 2012. StemCells, Inc. is the guarantor of Stem Cell Sciences (U.K.) Ltd’s obligations under the existing lease.

With the exception of the operating leases discussed above, we have not entered into any significant off balance sheet financial arrangements and have not established any special purpose entities. We have not guaranteed any debts or commitments of other entities or entered into any options on non-financial assets.

Contingencies

In July 2006, we filed suit against Neuralstem, Inc. in the Federal District Court for the District of Maryland, alleging that Neuralstem’s activities violate claims in four of the patents we exclusively licensed from NeuroSpheres, specifically U.S. Patent No. 6,294,346 (claiming the use of human neural stem cells for drug screening), U.S. Patent No. 7,101,709 (claiming the use of human neural stem cells for screening biological agents), U.S. Patent No. 5,851,832 (claiming methods for proliferating human neural stem cells), and U.S. Patent No. 6,497,872 (claiming methods for transplanting human neural stem cells). In May 2008, we filed a second patent infringement suit against Neuralstem and its two founders, Karl Johe and Richard Garr. In this suit, which we filed in the Federal District Court for the Northern District of California, we allege that Neuralstem’s activities infringe claims in two patents we exclusively license from NeuroSpheres, specifically U.S. Patent No. 7,361,505 (claiming composition of matter of human neural stem cells derived from any source material) and U.S. Patent No. 7,115,418 (claiming methods for proliferating human neural stem cells). In addition, we allege various state law causes of action against Neuralstem arising out of its repeated derogatory statements to the public about our patent portfolio. Also in May 2008, Neuralstem filed suit against us and NeuroSpheres in the Federal District Court for the District of Maryland seeking a declaratory judgment that the ‘505 and ‘418 patents are either invalid or are not infringed by Neuralstem and that Neuralstem has not violated California state law. In August 2008, the California court transferred our lawsuit against Neuralstem to Maryland for resolution on the merits. In July 2009, the Maryland District Court granted our motion to consolidate these two cases with the litigation we initiated against Neuralstem in 2006. Discovery is ongoing in these cases and we anticipate a trial date in 2013.

In addition to the actions described above, in April 2008, we filed an opposition to Neuralstem’s European Patent No. 0 915 968 (methods of isolating, propagating and differentiating CNS stem cells), because the claimed invention is believed by us to be unpatentable over prior art, including the patents exclusively licensed by us from NeuroSpheres. In December 2010, the European Patent Office ruled that all composition claims in Neuralstem’s ‘968 European patent were invalid and unpatentable over prior art including several of the NeuroSpheres patents licensed to us. Neuralstem has appealed this decision.

Effective 2008, as part of an indemnification agreement with NeuroSpheres, we are entitled to offset all litigation costs incurred in this patent infringement suit, against amounts that would otherwise be owed to NeuroSpheres under our exclusive license agreements with NeuroSpheres, such as annual maintenance fees, milestones and royalty payments. Under the terms of our license agreements, we are required to make annual payments of $50,000 to NeuroSpheres, and we expect to make these annual payments through the remaining life of the patent which, at December 31, 2010, was approximately 14 years. We have therefore capitalized $700,000 (14 years at $50,000 per year) to offset litigation costs. The amount capitalized is not dependent on the achievement of any milestones or related to any other contingent payments which may become due under the arrangement. We will reduce this asset by $50,000 per year in lieu of the cash payments due to NeuroSpheres. As the $50,000 annual payments are fully creditable against royalties due to NeuroSpheres, we have classified the capitalized amount as prepaid royalties under “Other assets, non-current” on our accompanying Consolidated Balance Sheets. We have concluded that the estimated balance of $650,000, as of September 30, 2012, is a fair estimate and realizable against future milestone and royalty payments to NeuroSpheres, and that litigation costs incurred above this amount will be expensed as incurred. Management will reevaluate this estimate on a quarterly basis based on actual costs and other relevant factors.

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Warrant Liability

9 Months Ended

Sep. 30, 2012

Warrant Liability [Abstract]

Warrant Liability

Note 8. Warrant Liability

We use various option pricing models, such as the Black-Scholes option pricing model and a Monte Carlo simulation model, to estimate fair value of warrants issued. In using these models, we make certain assumptions about risk-free interest rates, dividend yields, volatility, expected term of the warrants and other assumptions. Risk-free interest rates are derived from the yield on U.S. Treasury debt securities. Dividend yields are based on our historical dividend payments, which have been zero to date. Volatility is estimated from the historical volatility of our common stock as traded on NASDAQ. The expected term of the warrants is based on the time to expiration of the warrants from the date of measurement.

In November 2008, we sold 1,379,310 units to institutional investors at a price of $14.50 per unit, for gross proceeds of $20,000,000. The units, each of which consisted of one share of common stock and a warrant to purchase 0.75 shares of common stock at an exercise price of $23.00 per share, were offered as a registered direct offering under a shelf registration statement previously filed with, and declared effective by, the SEC. We received total proceeds, net of offering expenses and placement agency fees, of approximately $18,637,000. We recorded the fair value of the warrants to purchase 1,034,483 shares of our common stock as a liability. The fair value of the warrant liability is revalued at the end of each reporting period, with the change in fair value of the warrant liability recorded as a gain or loss in our condensed consolidated statements of operations. The fair value of the warrants will continue to be classified as a liability until such time as the warrants are exercised, expire or an amendment of the warrant agreement renders these warrants to be no longer classified as a liability.

The assumptions used for the Black-Scholes option pricing model are as follows:

	To Calculate Fair Value of Warrant Liability at
	September 30, 2012			December 31, 2011
Expected life (years)		1.6			2.4
Risk-free interest rate		0.2	%		0.3	%
Expected volatility		108.1	%		74.1	%
Expected dividend yield		0	%		0	%

	At September 30, 2012		At December 31, 2011		Change in Fair Value of Warrant Liability
Fair value of liability for warrants issued in 2008	$	129,785	$	2,224	$	127,561

In November 2009, we sold 1,000,000 units to institutional investors at a price of $12.50 per unit, for gross proceeds of $12,500,000. The units, each of which consisted of one share of common stock and a warrant to purchase 0.40 shares of common stock at an exercise price of $15.00 per share, were offered as a registered direct offering under a shelf registration statement previously filed with, and declared effective by, the SEC. We received total proceeds, net of offering expenses and placement agency fees, of approximately $11,985,000. We recorded the fair value of the warrants to purchase 400,000 shares of our common stock as a liability. The fair value of the warrant liability is revalued at the end of each reporting period, with the change in fair value of the warrant liability recorded as a gain or loss in our condensed consolidated statements of operations. The fair value of the warrants will continue to be classified as a liability until such time as the warrants are exercised, expire or an amendment of the warrant agreement renders these warrants to be no longer classified as a liability.

The assumptions used for the Black-Scholes option pricing model are as follows:

	To Calculate Fair Value of Warrant Liability at
	September 30, 2012			December 31, 2011
Expected life (years)		2.6			3.3
Risk-free interest rate		0.3	%		0.5	%
Expected volatility		90.1	%		90.8	%
Expected dividend yield		0	%		0	%

	At September 30, 2012		At December 31, 2011		Change in Fair Value of Warrant Liability
Fair value of liability for warrants issued in 2009	$	104,703	$	28,971	$	75,732

In December 2011, we raised gross proceeds of $10,000,000 through a public offering of 8,000,000 units and 8,000,000 Series B Warrants. The combination of units and Series B Warrants were sold at a public offering price of $1.25 per unit. Each Series B Warrant gave the holder the right to purchase one unit at an exercise price of $1.25 per unit and was exercisable until May 2, 2012, the 90th trading day after the date of issuance. Each unit consists of one share of our common stock and one Series A Warrant. Each Series A Warrant gives the holder the right to purchase one share of our common stock at an initial exercise price of $1.40 per share. The Series A Warrants are immediately exercisable upon issuance and will expire on the fifth anniversary of the closing date of the initial financing transaction in December 2011. The shares were offered under our shelf registration statement previously filed with previously filed with, and declared effective by, the SEC.

In the first and second quarter of 2012, an aggregate of 2,700,000 Series B Warrants were exercised. For the exercise of these warrants, we issued 2,700,000 shares of our common stock and 2,700,000 Series A Warrants with an initial exercise price of $1.40 per share and received gross proceeds of $3,375,000. The remaining 5,300,000 Series B Warrants expired unexercised by their terms on May 2, 2012.

In the third quarter of 2012, an aggregate of 1,445,400 Series A Warrants were exercised. For the exercise of these warrants, we issued 1,445,400 shares of our common stock and received gross proceeds of $977,900 and $1,045,660 in the third and fourth quarter of 2012 respectively.

The assumptions used for the Monte Carlo simulation model to value the Series A Warrants at September 30, 2012 are as follows:

Risk-free interest rate per year	0.5	%
Expected volatility per year	95.3	%
Expected dividend yield	0	%
Expected life in years	4.2

The use of a Monte Carlo simulation model requires the input of additional subjective assumptions including the progress of our R&D programs and its affect on potential future financings.

The following table is a summary of the changes in fair value of warrant liability for the Series A Warrants for the three-month period ended September 30, 2012:

	Series A
	Number of Warrants			Fair value $
Balance at June 30, 2012		10,700,000		$	5,390,018
Less exercised		(1,445,400	)		(728,106	)
Changes in fair value		—			9,586,748
Balance at September 30, 2012		9,254,600		$	14,248,660

The following table is a summary of our outstanding warrants and fair value of our warrant liability as of September 30, 2012:

Warrants	Number Outstanding		Exercise Price ($) per share		Fair value
Warrants issued in 2008		1,034,483		23.00	$	129,785
Warrants issued in 2009		400,000		15.00		104,703
Series A Warrants		9,254,660		1.40		14,248,660
Total		10,689,143			$	14,483,148

The fair value of the warrant liability is revalued at the end of each reporting period, with the change in fair value of the warrant liability recorded as a gain or loss in our condensed consolidated statements of operations. The fair value of the warrants will continue to be classified as a liability until such time as the warrants are exercised, expire or an amendment of the warrant agreement renders these warrants to be no longer classified as a liability.

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California Institute for Regenerative Medicine Funding Program

9 Months Ended

Sep. 30, 2012

California Institute for Regenerative Medicine Funding Program [Abstract]

California Institute for Regenerative Medicine Funding Program

Note 10. California Institute for Regenerative Medicine Funding Program

In July 2012, the California Institute for Regenerative Medicine (CIRM) approved an award to us for up to $20 million under CIRM’s Disease Team Therapy Development Award program (RFA 10-05). The award is to fund preclinical development of our HuCNS-SC cells in cervical spinal cord injury over a maximum four-year period, with the goal of filing an investigational new drug application (IND) in that time.

In September 2012, CIRM approved a second award to us for up to $20 million under RFA 10-05. The award is to fund preclinical development of our proprietary HuCNS-SC cells in Alzheimer’s disease over a maximum four-year period, with the goal of filing an IND in that time.

Funding to for-profit companies under RFA 10-05 is expected to be structured as forgivable loans, in accordance with mutually agreed upon terms and conditions and CIRM regulations. As of September 30, 2012, we and CIRM were in discussions regarding the terms and conditions of the funding, and no funds had yet been disbursed to us from CIRM.

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Goodwill and Other Intangible Assets (Details 1) (USD $)	9 Months Ended
	Sep. 30, 2012
Changes in goodwill
Balance as of December 31, 2011	$ 1,895,000
Foreign currency translation	72,570
Balance as of September 30, 2012	$ 1,967,570

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Warrant Liability (Details Textual) (USD $)	1 Months Ended			3 Months Ended	9 Months Ended	12 Months Ended	3 Months Ended		6 Months Ended	9 Months Ended	12 Months Ended	1 Months Ended			6 Months Ended	9 Months Ended	12 Months Ended
	May 02, 2012	Nov. 30, 2009	Nov. 30, 2008	Sep. 30, 2012	Sep. 30, 2012	Dec. 31, 2011	Dec. 31, 2012 Series A Warrants [Member]	Sep. 30, 2012 Series A Warrants [Member]	Jun. 30, 2012 Series A Warrants [Member]	Sep. 30, 2012 Series A Warrants [Member]	Dec. 31, 2011 Series A Warrants [Member]	May 02, 2012 Series B Warrant [Member]	Nov. 30, 2009 Series B Warrant [Member]	Nov. 30, 2008 Series B Warrant [Member]	Jun. 30, 2012 Series B Warrant [Member]	Sep. 30, 2012 Series B Warrant [Member]	Dec. 31, 2011 Series B Warrant [Member]
Warrant Liability (Textual) [Abstract]
Gross proceeds	$ 5,300,000			$ 3,375,000	$ 4,153,584		$ 1,045,660	$ 977,900				$ 5,300,000	$ 12,500,000	$ 20,000,000		$ 3,375,000	$ 10,000,000
Number of shares of common stock								1,445,400	2,700,000	1,445,400			0.40	0.75		2,700,000
Exercise price		15.00	23.00		1.40
Warrants issued													400,000	1,034,483
Warrants sold at public offering price																	1.25
Exercise price of warrant																1.40	1.25
Exercise price of common stock											$ 1.40
Number of warrants exercised					688,171			1,445,400		1,445,400					2,700,000	2,700,000
Number of units raised through public offering																	8,000,000
Warrants issued										2,700,000						2,700,000
Warrant Liability (Additional Textual) [Abstract]
Units sold to institutional investors		1,000,000	1,379,310
Price per unit sold to institutional investors		$ 12.50	$ 14.50
Total proceeds, net of offering expenses and placement agency fees		$ 11,985,000	$ 18,637,000
Date of issuance warrant						90th trading day

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Fair Value Measurement (Tables)

9 Months Ended

Sep. 30, 2012

Fair Value Measurement [Abstract]

Financial assets and liabilities measured at fair value

	Fair Value Measurement at Report Date Using
	Quoted Prices in Active Markets for Identical Assets (Level 1)		Significant Other Observable Inputs (Level 2)		Unobservable Inputs (Level 3)		As of September 30, 2012
Financial assets:
Cash equivalents:
Money market funds	$	1,170,798	$	—	$	—	$	1,170,798
U.S. Treasury debt obligations		14,260,825		—		—		14,260,825
Marketable securities:
Debt securities		—		6,031,735		—		6,031,735
Total financial assets	$	15,431,623	$	6,031,735	$	—	$	21,463,358
Financial liabilities:
Bond obligation	$	—	$	381,250	$	—	$	381,250
Warrant liabilities		—		234,488		14,248,660		14,483,148
Total financial liabilities	$	—	$	615,738	$	14,248,660	$	14,864,398

Roll forward for financial assets and liabilities measured at fair value using significant Other observable inputs (Level 2)

	Level 2 Beginning Balance 12/31/11 $		Net transfers (to) from Level 1 $		Change included in earnings $		Settled $			Level 2 Ending Balance 09/30/12 $
Marketable debt securities		3,280,591		2,751,144		—		—			6,031,735
Bond obligation		522,500		—		—		(141,250	)		381,250
Warrant liabilities		31,195		—		203,293		—			234,488

Roll forward for liabilities measured at fair value using significant unobservable inputs (Level 3)

	Warrant Liabilities
Balance at December 31, 2011	$	6,011,120
Less fair value of warrants exercised		(1,823,907	)
Less fair value of warrants expired		(3,560,063	)
Add fair value of warrants issued		1,714,436
Add change in fair value of warrants		11,907,074
Balance at September 30, 2012	$	14,248,660

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Summary of Significant Accounting Policies (Details) (USD $)	3 Months Ended		9 Months Ended
	Sep. 30, 2012	Sep. 30, 2011	Sep. 30, 2012	Sep. 30, 2011
Reconciliation of the numerators and denominators of the basic and diluted earnings per share computations
Net loss	$ (16,336,790)	$ (4,334,352)	$ (25,732,707)	$ (14,116,780)
Weighted average shares outstanding used to compute basic and diluted net income or loss per share	30,168,475	14,009,341	25,992,764	13,831,749
Basic and diluted net loss per share	$ (0.54)	$ (0.31)	$ (0.99)	$ (1.02)

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Warrant Liability (Details 3) (USD $)	3 Months Ended
	Sep. 30, 2012
Summary of changes in fair value of warrant liability
Number of warrants exercised	(1,445,400)
Fair value of warrants exercised	$ (728,106)
Number of warrants, ending balance	10,689,143
Series A Warrants [Member]
Summary of changes in fair value of warrant liability
Number of warrants, beginning balance	10,700,000
Fair value of warrant liability, beginning balance	5,390,018
Fair value, changes in fair value at period end	9,586,748
Fair value of warrant liability, ending balance	$ 14,248,660
Number of warrants, ending balance	9,254,600

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Stock-Based Compensation (Details 3) (Restricted stock units [Member], USD $)	3 Months Ended
	Sep. 30, 2012
Restricted stock units [Member]
Unvested restricted stock units
Number of RSUs, Beginning balance	1,467,533
Number of RSUs, Granted	52,000
Number of RSUs, Vested	(3,333)
Number of RSUs, Cancelled
Number of RSUs, Ending balance	1,516,200
Weighted-average grant date fair value per RSU, Beginning balance	$ 2.12
Weighted-average grant date fair value per RSU, Granted	$ 2.15
Weighted-average grant date fair value per RSU, Vested	$ 12.59
Weighted-average grant date fair value per RSU, Cancelled
Weighted-average grant date fair value per RSU, Ending balance	$ 2.10

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Condensed Consolidated Statements of Comprehensive Income (Unaudited) (USD $)	3 Months Ended		9 Months Ended
	Sep. 30, 2012	Sep. 30, 2011	Sep. 30, 2012	Sep. 30, 2011
Condensed Consolidated Statements of Comprehensive Income [Abstract]
Net loss	$ (16,336,790)	$ (4,334,352)	$ (25,732,707)	$ (14,116,780)
Other comprehensive income (loss)
Foreign currency translation adjustments	98,706	(133,593)	125,854	66,441
Unrealized gains (losses) on marketable securities	587	(5,413)	3,210	(123,905)
Other comprehensive income (loss)	99,293	(139,006)	129,064	(57,464)
Comprehensive loss	$ (16,237,497)	$ (4,473,358)	$ (25,603,643)	$ (14,174,244)

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Goodwill and Other Intangible Assets

9 Months Ended

Sep. 30, 2012

Goodwill and Other Intangible Assets [Abstract]

Goodwill and Other Intangible Assets

Note 4. Goodwill and Other Intangible Assets

On April 1, 2009, we acquired the operations of Stem Cell Sciences Plc (SCS) for an aggregate purchase price of approximately $5,135,000. The acquired operations includes proprietary cell technologies relating to embryonic stem cells, induced pluripotent stem (iPS) cells, and tissue-derived (adult) stem cells; expertise and infrastructure for providing cell-based assays for drug discovery; a cell culture products business; and an intellectual property portfolio with claims relevant to cell processing, reprogramming and manipulation, as well as to gene targeting and insertion.

The purchase price was allocated as follows:

	Allocated purchase Price		Estimated life of intangible assets in years
Net tangible assets	$	36,000
Intangible assets:
Customer relationships and developed technology		1,310,000		6 to 9
In-process research and development		1,340,000		N/A
Trade name		310,000		15
Goodwill		2,139,000		N/A
Total	$	5,135,000

In-process research and development assets relate to: 1) the acquisition of certain intellectual property rights not expected to expire until 2027 related to our program focused on developing genetically engineered rat models of human disease (our “Transgenic Rat Program”); and 2) the acquisition of certain technology related to the commercialization of our SC Proven cell culture products and the development and commercialization of cell-based assay platforms for use in drug discovery and development (our “Assay Development Program”).

At the time of valuation (April 2009), our Transgenic Rat Program was in its nascent stage and our Assay Development Program was expected to achieve proof of concept by 2012. Neither program was expected to begin generating revenue until 2011-2012. In December 2011, in part because of management’s decision to focus on our therapeutic product development programs and not to allocate time and resources to the assays technology, we determined that we could not predict the future cash flows from the intangible IPR&D asset related to the Assay Development Program. Therefore, at December 31, 2011, we determined that the intangible asset was impaired and wrote off the approximately $655,000 carrying value of the asset.

Trade name relates to the “SC Proven” trademark of our cell culture products which we expect to market for 15 years from the date of acquisition, based on which, we estimated a remaining useful life of 15 years from the valuation date.

The following table presents changes in goodwill:

Balance as of December 31, 2011	$	1,895,000
Foreign currency translation		72,570
Balance as of September 30, 2012	$	1,967,570

The components of our other intangible assets at September 30, 2012 are summarized below:

Other Intangible Asset Class	Cost		Impairment			Accumulated Amortization			Foreign Currency Translation		Net Carrying Amount
Customer relationships and developed technology	$	1,310,000	$	—		$	(647,222	)	$	146,820	$	809,598
In-process research and development		1,340,000		(654,961	)		(270,687	)		131,710		546,062
Trade name		310,000		—			(79,716	)		35,936		266,220
Patents		979,612		—			(724,516	)		—		255,096
Total other intangible assets	$	3,939,612	$	(654,961	)	$	(1,722,141	)	$	314,466	$	1,876,976

Amortization expense was approximately $66,000 in the third quarter of 2012.

The expected future annual amortization expense for each of the next five years based on current balances of our intangible assets is approximately as follows:

For the year ending December 31:
2013	$	267,000
2014	$	267,000
2015	$	266,000
2016	$	261,000
2017	$	238,000

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Summary of Significant Accounting Policies (Details 1)	Sep. 30, 2012	Sep. 30, 2011
Outstanding potentially dilutive common stock
Total	12,680,199	2,668,486
Options [Member]
Outstanding potentially dilutive common stock
Total	474,917	895,962
Restricted stock units [Member]
Outstanding potentially dilutive common stock
Total	1,516,199	338,041
Warrant [Member]
Outstanding potentially dilutive common stock
Total	10,689,083	1,434,483

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Stock-Based Compensation (Details) (USD $)	3 Months Ended		9 Months Ended
	Sep. 30, 2012	Sep. 30, 2011	Sep. 30, 2012	Sep. 30, 2011
Share-based Compensation [Abstract]
Total employee stock-based compensation expense	$ 767,153	$ 664,384	$ 2,227,144	$ 2,613,111
Effect on basic and diluted net loss per share	$ (0.03)	$ (0.05)	$ (0.09)	$ (0.19)
Research and development expense [Member]
Share-based Compensation [Abstract]
Total employee stock-based compensation expense	314,393	343,845	966,570	1,304,846
Selling, general and administrative expense [Member]
Share-based Compensation [Abstract]
Total employee stock-based compensation expense	$ 452,760	$ 320,539	$ 1,260,574	$ 1,308,265

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Financial Instruments (Tables)

9 Months Ended

Sep. 30, 2012

Financial Instruments [Abstract]

Available-for-sale marketable securities

	Amortized Cost		Gross Unrealized Gains		Gross Unrealized (Losses)			Fair Value
September 30, 2012
Cash	$	281,065	$	—	$	—		$	281,065
Cash equivalents		15,431,623		—		—			15,431,623
Marketable debt securities, current		6,031,219		516		—			6,031,735
Total cash, cash equivalents, and marketable securities	$	21,743,907	$	516	$	—		$	21,744,423
December 31, 2011
Cash	$	291,093	$	—	$	—		$	291,093
Cash equivalents		13,020,168		—		—			13,020,168
Marketable debt securities, current		3,283,209		—		(2,618	)		3,280,591
Total cash, cash equivalents, and marketable securities	$	16,594,470	$	—	$	(2,618	)	$	16,591,852