Exhibit 23.1

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

We have issued our report, dated March 14, 2007, on the financial statements and internal controls over financial reporting of Nanophase Technologies Corporation as of December 31, 2006. We hereby consent to the use of our report in the Registration Statement on Form S-3 of Nanophase Technologies Corporation. We also consent to the reference to our Firm under the caption “Experts” in the Prospectus.

Schaumburg, Illinois
May 22, 2007

/s/ McGladrey & Pullen, LLP  

McGladrey & Pullen, LLP