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Consolidated Statements of Stockholders' Deficit Parentheticals - shares
shares in Thousands
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Exercise of stock options, net (in shares) 3,044    
Employee stock purchase plan sales, net (in shares) 260 321 246
Issuance of common stock, net (in shares)   3,846 22,044
Warrants issued (in shares)     3,511
Warrants exercised (in shares) 253    
Common Stock      
Exercise of stock options, net (in shares)   3,299 510
Employee stock purchase plan sales, net (in shares) 260 321 246