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Note 9 - Debt Textual (Details)
$ in Thousands
1 Months Ended 12 Months Ended
Dec. 07, 2020
USD ($)
Feb. 05, 2019
USD ($)
Dec. 31, 2020
USD ($)
Dec. 31, 2022
USD ($)
Dec. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Dec. 28, 2022
Jul. 29, 2022
USD ($)
Debt Instrument [Line Items]                
Repayments of lines of credit       $ 0 $ 0 $ 52,420    
Long-term debt, total     $ 122,609   298,142 122,609    
MidCap Financial Services, LLC | Senior Credit Facility                
Debt Instrument [Line Items]                
Debt instrument, face amount   $ 100,000            
Repayments of lines of credit $ 43,298              
Debt instrument, basis spread on variable rate   8.00%            
Debt instrument, minimum LIBOR   0.50%            
Debt instrument, term (month)   30 months            
Extinguishment of debt, amount     40,000          
Payment for debt extinguishment or debt prepayment cost     3,298          
Write off of deferred debt issuance cost     $ 1,211     $ 1,211    
Credit Agreement | Athyrium                
Debt Instrument [Line Items]                
Debt instrument, face amount $ 200,000              
Debt instrument, LIBOR floor 1.75%              
Debt instrument, LIBOR cap 3.50%     3.50%        
Debt instrument, exit fee, percentage of principal 2.00%              
Debt instrument, commitment fee percentage 1.00%              
Long-term debt, gross       $ 200,000        
Paid-in-kind interest       23,387 16,009      
Long-term debt, total       $ 240,452        
Effective interest rate       11.88%        
Credit Agreement | Athyrium | Prior to the Second Anniversary                
Debt Instrument [Line Items]                
Debt instrument, prepayment fee, percentage of principal voluntary payments 102.00%              
Debt instrument, prepayment fee, percentage of accrued interest 0.0050              
Credit Agreement | Athyrium | Between the Second and Third Anniversaries                
Debt Instrument [Line Items]                
Debt instrument, prepayment fee, percentage of principal voluntary payments 2.00%              
Credit Agreement | Athyrium | Between the Third and Fourth Anniversaries                
Debt Instrument [Line Items]                
Debt instrument, prepayment fee, percentage of principal voluntary payments 1.00%              
Credit Agreement | Athyrium | After Fourth Anniversary                
Debt Instrument [Line Items]                
Debt instrument, prepayment fee, percentage of principal voluntary payments 0.00%              
Credit Agreement | Athyrium | Term Loan A Drawn                
Debt Instrument [Line Items]                
Debt instrument, covenant, minimum unrestricted cash and cash equivalents $ 15,000              
Credit Agreement | Athyrium | Term Loan A and B Drawn                
Debt Instrument [Line Items]                
Debt instrument, covenant, minimum unrestricted cash and cash equivalents 20,000              
Credit Agreement | Athyrium | Term Loans A, B and C Drawn                
Debt Instrument [Line Items]                
Debt instrument, covenant, minimum unrestricted cash and cash equivalents 15,000              
Credit Agreement | Athyrium | Term Loans A, B and C Drawn and Cure Right Exercised                
Debt Instrument [Line Items]                
Debt instrument, covenant, minimum unrestricted cash and cash equivalents $ 20,000              
Credit Agreement | Athyrium | London Interbank Offered Rate (LIBOR)                
Debt Instrument [Line Items]                
Debt instrument, basis spread on variable rate 8.25%     8.25%        
Debt Instrument Libor Interest Rate             0.0473  
Credit Agreement | Athyrium | London Interbank Offered Rate (LIBOR) | PIK Interest Payment is Made                
Debt Instrument [Line Items]                
Debt instrument, basis spread on variable rate 10.25%              
Credit Agreement | Athyrium | Term A Loan                
Debt Instrument [Line Items]                
Proceeds from issuance of long-term Debt, total $ 125,000              
Debt instrument, unamortized discount (premium) and debt issuance costs, net, total       $ 12,828 8,483      
Amortization of debt issuance costs       $ 916 $ 531      
Credit Agreement | Athyrium | Term B Loan                
Debt Instrument [Line Items]                
Debt instrument, face amount               $ 25,000
Credit Agreement | Athyrium | Term C Loan                
Debt Instrument [Line Items]                
Debt instrument, face amount               50,000
Credit Agreement | Athyrium | Term B And C Loan                
Debt Instrument [Line Items]                
Debt instrument, face amount               75,000
Deferred debt fees and issuance costs               $ 3,428
Credit Agreement | Athyrium | Term Loans                
Debt Instrument [Line Items]                
Effective interest rate       12.87% 12.17%      
Secured Credit Facility, First Tranche | MidCap Financial Services, LLC | Senior Credit Facility                
Debt Instrument [Line Items]                
Debt instrument, face amount   $ 50,000            
Repayments of long-term debt, total   30,000            
Secured Credit Facility, Second Tranche | MidCap Financial Services, LLC | Senior Credit Facility                
Debt Instrument [Line Items]                
Debt instrument, face amount   30,000            
Secured Credit Facility, Third Tranche | MidCap Financial Services, LLC | Senior Credit Facility                
Debt Instrument [Line Items]                
Debt instrument, face amount   $ 20,000