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Note 1 - Significant Accounting Policies and Concentrations of Risk Textual (Details) - USD ($)
$ in Thousands
1 Months Ended 12 Months Ended
Dec. 31, 2020
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Significant Accounting Policies and Concentrations of Risk [Line Items]        
Restricted cash   $ 1,472 $ 3,345  
Long-term investment maturity, minimum (in months)   12 years    
Inventory adjustments   $ 932    
Reserves   (1,177) (245)  
Advertising expense   14,891 5,705 $ 6,567
Interest expense, debt, total   99,092 59,294 14,501
Amortization of debt financing costs and original issue discounts   $ (916) $ (531) $ 1,217
Antidilutive securities excluded from computation of earnings per share, amount (in shares)   25,596 26,034 14,957
Reclassification from accumulated other comprehensive income, current period, before tax     $ 1  
Foreign Exchange Contract | Not Designated as Hedging Instrument        
Significant Accounting Policies and Concentrations of Risk [Line Items]        
Derivative, loss on derivative       $ 632
Derivative, gain on derivative       662
Computer Equipment        
Significant Accounting Policies and Concentrations of Risk [Line Items]        
Property, plant and equipment, useful life (in years)   3 years    
Laboratory Equipment, Office Equipment and Software        
Significant Accounting Policies and Concentrations of Risk [Line Items]        
Property, plant and equipment, useful life (in years)   5 years    
Furniture and fixtures        
Significant Accounting Policies and Concentrations of Risk [Line Items]        
Property, plant and equipment, useful life (in years)   7 years    
Royalty Receivable        
Significant Accounting Policies and Concentrations of Risk [Line Items]        
Restricted cash   $ 23 1,924  
Collateral for Credit        
Significant Accounting Policies and Concentrations of Risk [Line Items]        
Restricted cash   $ 1,449 $ 1,421  
Maximum        
Significant Accounting Policies and Concentrations of Risk [Line Items]        
Maturity period of high quality marketable securities (in years)   3 years    
Average maturity period of high quality marketable securities (in months)   12 months    
Maturity period of short term investment (in months)   12 months    
Senior Credit Facility | MidCap Financial Services, LLC        
Significant Accounting Policies and Concentrations of Risk [Line Items]        
Write off of deferred debt issuance cost $ 1,211     $ 1,211