Significant Accounting Policies (Details Textual) (USD $) In Thousands, unless otherwise specified	3 Months Ended		6 Months Ended		12 Months Ended
	Jun. 30, 2012	Jun. 30, 2011	Jun. 30, 2012	Jun. 30, 2011	Dec. 31, 2011	Mar. 09, 2011
Significant Accounting Policies (Textual) [Abstract]
Royalty and milestone payments						$ 30,000
Manufacturing cost of finished goods	3,980		3,980		3,980
Cumulative mark-to-market adjustments - loss	997	998	959	2,340
Hedge collateral under the agreement	4,970		4,970
Potential common shares			9,172	8,128
Average maturity for portfolio investments			24 months
Gross Unrealized Gains	(9)	9		(14)
Significant Accounting Policies (Additional Textual) [Abstract]
Research and development expenses		387		858
Additional Research and development expenses		80		176
Restricted cash	300		300
Maturity of investments			12 months
Reduction in supplies inventory and related reserve					635
Manufacturing cost of finished goods	3,980		3,980		3,980
Accrued expenses	5,459		5,459		8,622
Interest expenses	1,160	1,166	2,320	1,455
Amortization of deferred financing costs	110	105	220	136
Cumulative mark-to-market adjustments - loss	997	998	959	2,340
Hedge collateral under the agreement	4,970		4,970
Potential common shares			9,172	8,128
Average maturity for portfolio investments			24 months
Amortization of deferred financing costs			220	137
Maximum [Member]
Significant Accounting Policies (Textual) [Abstract]
Maturity period for high-quality marketable securities			3 years
Average portfolio maturity period for high-quality marketable securities			2 years
Maturity period of investments			12 months
Minimum [Member]
Significant Accounting Policies (Textual) [Abstract]
Maturity period of investments			3 months
JPR Royalty Sub LLC [Member]
Significant Accounting Policies (Textual) [Abstract]
Royalty and milestone payments						30,000
Shionogi (Japan) [Member]
Significant Accounting Policies (Textual) [Abstract]
Collateral credit card program in royalty revenue paid	1,930		1,930
RAPIACTA [Member]
Significant Accounting Policies (Textual) [Abstract]
Royalty payments received			$ 1,666		$ 1,216