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Note 8 - Royalty Monetizations (Tables)
12 Months Ended
Dec. 31, 2021
Notes Tables  
Royalty Financing Obligations [Table Text Block]
  

2020 RPI Royalty Agreement

  

2021 RPI Royalty Agreement

  

OMERS Royalty Agreement

  

Total

 

2020 Royalty sale: Royalty financing obligation, net of issuance costs

 $122,609  $  $  $122,609 

Non-cash Interest expense on Royalty financing obligation

  2,108         2,108 

Balance as of December 31, 2020

 $124,717  $  $  $124,717 

2021 Royalty sale: Royalty financing obligations, net of issuance costs

     150,833   147,309   298,142 

Non-cash Interest expense on Royalty financing obligations

  33,308   2,897   1,465   37,670 

Royalty revenues paid and payable

  (10,801)  (353)     (11,154)

Balance as of December 31, 2021

 $147,224  $153,377  $148,774  $449,375 
                 

Effective interest rate

  27.3%  16.5%  8.5%