Consolidated Statements of Comprehensive Loss (Unaudited) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2021	Jun. 30, 2020	Jun. 30, 2021	Jun. 30, 2020
Revenues:
Revenues	$ 49,959	$ 2,871	$ 69,018	$ 7,694
Expenses
Cost of product sales	297	0	6,220	0
Research and development	52,873	27,498	95,308	57,365
Selling, general and administrative	26,325	13,883	48,439	29,748
Royalty	46	0	10	69
Total operating expenses	79,541	41,381	149,977	87,182
Loss from operations	(29,582)	(38,510)	(80,959)	(79,488)
Interest and other income	13	2,758	39	9,204
Interest expense	(13,495)	(2,918)	(26,399)	(5,965)
(Loss) gain on foreign currency	(134)	63	(163)	43
Net loss	(43,198)	(38,607)	(107,482)	(76,206)
Foreign currency translation adjustment	(92)	0	86	0
Unrealized (loss) gain on available for sale investments	(3)	(11)	(2)	(36)
Comprehensive loss	$ (43,293)	$ (38,618)	$ (107,398)	$ (76,242)
Basic and diluted net loss per common share (in dollars per share)	$ (240)	$ (240)	$ (600)	$ (480)
Weighted average shares outstanding (in shares)	178,127	161,569	177,737	157,862
Product [Member]
Revenues:
Revenues	$ 33,430	$ 0	$ 51,301	$ 218
Royalty [Member]
Revenues:
Revenues	128	44	(769)	1,989
Milestone [Member]
Revenues:
Revenues	15,000	0	15,000	0
Collaborative and Other Research and Development [Member]
Revenues:
Revenues	$ 1,401	$ 2,827	$ 3,486	$ 5,487