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Contractual interest rate for funds borrowed, under the debt agreement.

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Amount, after accumulated amortization, of debt issuance costs. Includes, but is not limited to, legal, accounting, underwriting, printing, and registration costs.

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Contractual rate at which a foreign currency can be purchased or sold.

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Amount of increase in the fair value of derivatives recognized in the income statement.

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Fair value portion of notes payable.

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The cash inflow during the period from additional borrowings in aggregate debt. Includes proceeds from short-term and long-term debt.

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The cash inflow from amounts received from issuance of long-term debt that is wholly or partially secured by collateral. Excludes proceeds from tax exempt secured debt.

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Carrying value as of the balance sheet date, including the current and noncurrent portions, of collateralized debt obligations (with maturities initially due after one year or beyond the operating cycle, if longer). Such obligations include mortgage loans, chattel loans, and any other borrowings secured by assets of the borrower.

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Note 3 - Royalty Monetizations (Details Textual) $ in Thousands			12 Months Ended
	Dec. 07, 2020 USD ($)	Mar. 09, 2011 USD ($)	Dec. 31, 2020 USD ($)	Dec. 31, 2019 USD ($)	Dec. 31, 2018 USD ($)	Dec. 01, 2020 USD ($)	Nov. 30, 2020 ¥ / $
Proceeds from Issuance of Secured Debt			$ 119,867
Future Royalties Payable			124,717	$ 0
RPI 2019 Intermediate Finance Trust [Member]
Future Royalties Payable			125,000
RPI 2019 Intermediate Finance Trust [Member] \| ORLADEYO [Member]
Royalty Purchase Agreement, Royalties, Percentage of Sublicense Revenue in Other Markets	20.00%
RPI 2019 Intermediate Finance Trust [Member] \| ORLADEYO [Member] \| Annual Net Sales Under $350,000 [Member]
Royalty Purchase Agreement, Royalties, Percentage of Annual Net Sales in Key Territories	8.75%
RPI 2019 Intermediate Finance Trust [Member] \| ORLADEYO [Member] \| Annual Net Sales Between $350,000 and $550,000 [Member]
Royalty Purchase Agreement, Royalties, Percentage of Annual Net Sales in Key Territories	2.75%
RPI 2019 Intermediate Finance Trust [Member] \| ORLADEYO [Member] \| Annual Net Sales Over $550,000 [Member]
Royalty Purchase Agreement, Royalties, Percentage of Annual Net Sales in Key Territories	0.00%
RPI 2019 Intermediate Finance Trust [Member] \| ORLADEYO [Member] \| Annual Net Sales Under $150,000 [Member]
Royalty Purchase Agreement, Royalties, Percentage of Annual Net Sales in Other Markets	20.00%
RPI 2019 Intermediate Finance Trust [Member] \| ORLADEYO [Member] \| Annual Net Sales Between $150,000 and $230,000 [Member]
Royalty Purchase Agreement, Royalties, Percentage of Annual Net Sales in Other Markets	10.00%
RPI 2019 Intermediate Finance Trust [Member] \| ORLADEYO [Member] \| Annual Net Sales Over $230,000 [Member]
Royalty Purchase Agreement, Royalties, Percentage of Annual Net Sales in Other Markets	0.00%
RPI 2019 Intermediate Finance Trust [Member] \| BCX9930 [Member]
Royalty Purchase Agreement, Royalties, Percentage of Global Annual Net Sales	1.00%
RPI 2019 Intermediate Finance Trust [Member] \| Future Royalties Payable [Member]
Interest Payable			2,108
Proceeds from Issuance of Debt	$ 125,000
Debt Issuance Costs, Net, Total			$ 2,370
Debt Instrument, Interest Rate, Effective Percentage			24.00%
Foreign Exchange Contract [Member] \| Not Designated as Hedging Instrument [Member]
Derivative, Loss on Derivative			$ 632	347	$ 1,049
Derivative, Gain on Derivative			$ 662	$ 863	$ 941
PhaRMA Notes Member] \| Currency Hedge Agreement [Member]
Derivative, Forward Exchange Rate (in JPY per USD) \| ¥ / $							100
JPR Royalty Sub LLC [Member] \| PhaRMA Notes Member]
Private Placement of Senior Secured Notes		$ 30,000
Debt Instrument, Interest Rate, Stated Percentage		14.00%
Secured Debt, Total						$ 30,000
Interest Payable						$ 20,614
Percentage of Carrying Amount in Excess of Fair Value				3.00%
JPR Royalty Sub LLC [Member] \| PhaRMA Notes Member] \| Fair Value, Inputs, Level 2 [Member]
Notes Payable, Fair Value Disclosure				$ 30,000
JPR Royalty Sub LLC [Member] \| Royalty Monetization [Member]
Debt Instrument, Face Amount		$ 30,000
Proceeds from Issuance of Secured Debt		22,691
Transaction Costs		4,309
Interest Reserve		$ 3,000