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Note 2 - Stock-based Compensation (Details Textual)
$ / shares in Units, shares in Thousands
1 Months Ended 3 Months Ended 12 Months Ended
Aug. 31, 2013
shares
Mar. 31, 2017
USD ($)
$ / shares
shares
Mar. 31, 2016
USD ($)
shares
Dec. 31, 2014
shares
Dec. 31, 2016
shares
Number of Stock-based Compensation Plans   2      
Allocated Share-based Compensation Expense   $ 2,462,000 $ 2,645    
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized   19,865,000      
Employee Service Share-based Compensation Nonvested Awards Compensation Cost Expected to be Recognized For Remainder of Fiscal Year   6,313,000      
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Expected to be Recognized Year Two   6,402,000      
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Expected to be Recognized Year Three   4,482,000      
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Expected to be Recognized Year Four   2,344,000      
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Expected to be Recognized Year Five   324,000      
Incentive Plan [Member]          
Allocated Share-based Compensation Expense   $ 2,326,000 $ 2,556,000    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross | shares     0    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value | $ / shares   $ 3.75      
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant | shares   591     2,273
Incentive Plan [Member] | Employee Stock Option [Member] | Minimum [Member]          
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term   5 years      
Incentive Plan [Member] | Employee Stock Option [Member] | Maximum [Member]          
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term   10 years      
Incentive Plan [Member] | Employee Stock Option [Member] | Non-employee Directors [Member]          
Share-based Compensation Arrangement by Share-based Payment Award, First Vesting Period After Grant Date   1 year      
Incentive Plan [Member] | Employee Stock Option [Member] | Vest 25% Each Year Until Fully Vested [Member]          
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights, Percentage   25.00%      
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period   4 years      
Incentive Plan [Member] | Performance Shares [Member] | Vest Upon Successful Completion of Specific Development Milestones [Member]          
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross | shares 1,032     1,250  
Incentive Plan [Member] | Performance Shares [Member] | Vest Upon Successful Completion of Specific Development Milestones [Member] | August 2013 [Member]          
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights, Percentage   75.00%      
Share-based Compensation Arrangement by Shar-based Payment Award, Awards Unvested, Percentage   25.00%      
Incentive Plan [Member] | Performance Shares [Member] | Vest Upon Successful Completion of Specific Development Milestones [Member] | December 2014 [Member]          
Share-based Compensation Arrangement by Shar-based Payment Award, Awards Unvested, Percentage   100.00%      
Employee Stock Purchase Plan [Member]          
Allocated Share-based Compensation Expense   $ 136,000 $ 89,000    
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized | shares   1,475      
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant | shares   364      
Percentage of Salary to Purchase Common Stock, Maximum   15.00%      
Percentage of Common Stock Shares, Beginning   85.00%      
Share-based Compensation Arrangement by Share-based Payment Award, Maximum Number of Shares Per Employee | shares   3      
Shar-based Compensation Arrangement by Shar-based Payment Award, Maximum Number of Shares Per Employee, Amount   $ 25,000      
Stock Issued During Period, Shares, Employee Stock Purchase Plans | shares   58