Note 2 - Furniture and Equipment (Details) - Furniture and Equipment (USD $) In Thousands, unless otherwise specified	Dec. 31, 2014	Dec. 31, 2013
Property, Plant and Equipment [Line Items]
Furniture and Equipment	$ 14,232	$ 14,414
Less accumulated depreciation and amortization	(14,025)	(14,108)
Furniture and equipment, net	207	306
Furniture and Fixtures [Member]
Property, Plant and Equipment [Line Items]
Furniture and Equipment	542	600
Office Equipment [Member]
Property, Plant and Equipment [Line Items]
Furniture and Equipment	1,115	1,266
Software Development [Member]
Property, Plant and Equipment [Line Items]
Furniture and Equipment	1,423	1,448
Laboratory Equipment [Member]
Property, Plant and Equipment [Line Items]
Furniture and Equipment	5,786	5,721
Leased Equipment [Member]
Property, Plant and Equipment [Line Items]
Furniture and Equipment	63	63
Leasehold Improvements [Member]
Property, Plant and Equipment [Line Items]
Furniture and Equipment	$ 5,303	$ 5,316