Note 1 - Significant Accounting Policies and Concentrations of Risk (Details) - Summary of Receivables (USD $) In Thousands, unless otherwise specified	Dec. 31, 2014	Dec. 31, 2013
U.S. Department of Health and Human Services [Member] | Billed Revenues [Member]
Note 1 - Significant Accounting Policies and Concentrations of Risk (Details) - Summary of Receivables [Line Items]
Receivables	$ 2,778	$ 1,573
U.S. Department of Health and Human Services [Member] | Unbilled Revenues [Member]
Note 1 - Significant Accounting Policies and Concentrations of Risk (Details) - Summary of Receivables [Line Items]
Receivables	2,778	1,663
Shionogi & Co. Ltd. [Member] | Unbilled Revenues [Member]
Note 1 - Significant Accounting Policies and Concentrations of Risk (Details) - Summary of Receivables [Line Items]
Receivables	1,071	452
Billed Revenues [Member]
Note 1 - Significant Accounting Policies and Concentrations of Risk (Details) - Summary of Receivables [Line Items]
Receivables	2,778	1,573
Unbilled Revenues [Member]
Note 1 - Significant Accounting Policies and Concentrations of Risk (Details) - Summary of Receivables [Line Items]
Receivables	$ 3,849	$ 2,115