Exhibit 31.2

CERTIFICATIONS

I, Stuart Grant, certify that:

1.	I have reviewed this Amendment No. 1 to the annual report on Form 10-K/A of BioCryst Pharmaceuticals, Inc.; and
2.	Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report.

Date: January 19, 2011	/s/ Stuart Grant
	Stuart Grant
	Chief Financial Officer