<ARTICLE>                     5
<LEGEND>
This schedule contains summary financial information extracted from the BioCryst
Pharmaceuticals, Inc. Financial Statements, and is qualified in its entirety by
reference to such financial statements.


                             
<PERIOD-TYPE>                   9-MOS
<FISCAL-YEAR-END>                             Dec-31-2000
<PERIOD-END>                                  Sep-30-2000
<CASH>                                          8,774,555
<SECURITIES>                                   59,698,971
<RECEIVABLES>                                           0
<ALLOWANCES>                                            0
<INVENTORY>                                             0
<CURRENT-ASSETS>                               26,450,709
<PP&E>                                          5,226,548
<DEPRECIATION>                                  2,403,160
<TOTAL-ASSETS>                                 72,375,439
<CURRENT-LIABILITIES>                             932,514
<BONDS>                                                 0
<PREFERRED-MANDATORY>                                   0
<PREFERRED>                                             0
<COMMON>                                          175,361
<OTHER-SE>                                     71,142,925
<TOTAL-LIABILITY-AND-EQUITY>                   72,375,439
<SALES>                                                 0
<TOTAL-REVENUES>                                7,912,337
<CGS>                                                   0
<TOTAL-COSTS>                                           0
<OTHER-EXPENSES>                                9,689,456
<LOSS-PROVISION>                                        0
<INTEREST-EXPENSE>                                  2,823
<INCOME-PRETAX>                               (1,779,942)
<INCOME-TAX>                                            0
<INCOME-CONTINUING>                                     0
<DISCONTINUED>                                          0
<EXTRAORDINARY>                                         0
<CHANGES>                                               0
<NET-INCOME>                                  (1,779,942)
<EPS-BASIC>                                         (.10)
<EPS-DILUTED>                                       (.10)