FORM 6-K
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
Report of Foreign Issuer
Pursuant to Rule 13a-16 or 15d-16 of
the Securities Exchange Act of 1934
For the Month of August, 2012
Commission File Number 1-32001
Lorus Therapeutics Inc.
(Translation of registrant’s name into English)
2 Meridian Road, Toronto, Ontario M9W 4Z7
(Address of principal executive offices)
Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.
Form 20-F x Form 40-F ¨
Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1): ____
Note: Regulation S-T Rule 101(b)(1) only permits the submission in paper of a Form 6-K if submitted solely to provide an attached annual report to security holders.
Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7): ____
Note: Regulation S-T Rule 101(b)(7) only permits the submission in paper of a Form 6-K if submitted to furnish a report or other document that the registrant foreign private issuer must furnish and make public under the laws of the jurisdiction in which the registrant is incorporated, domiciled or legally organized (the registrant’s “home country”), or under the rules of the home country exchange on which the registrant’s securities are traded, as long as the report or other document is not a press release, is not required to be and has not been distributed to the registrant’s security holders, and, if discussing a material event, has already been the subject of a Form 6-K submission or other Commission filing on EDGAR.
Indicate by check mark whether the registrant by furnishing the information contained in this Form is also thereby furnishing the information to the Commission pursuant to Rule 12g3-2(b) under the Securities Exchange Act of 1934.
Yes ¨ No x
If “Yes” is marked, indicate below the file number assigned to the registrant in connection with Rule 12g3-2(b):82-_______________.
SIGNATURE
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.
Lorus Therapeutics Inc. | ||
Date: August 13, 2012 | By: | /s/ “Elizabeth Williams” |
Elizabeth Williams | ||
Director of Finance and Controller |
EXHIBIT INDEX
99.1 | News Release Dated June 14, 2012 - Lorus Therapeutics Announces Clinical Study Progress with its Anticancer Drug LOR-253 and Expansion to a Second Major Site |
99.2 | News Release Dated June 28, 2012 - Lorus Therapeutics Announces Issuance of Canadian Patent for Novel Anticancer Therapy IL-17E |
99.3 | News Release Dated August 8, 2012 - Lorus Therapeutics Reports Results for Fiscal Year 2012 |
Exhibit 99.1
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NEWS RELEASE |
Lorus Therapeutics Announces Clinical Study Progress with its Anticancer Drug LOR-253
and Expansion to a Second Major Site
TORONTO, CANADA, June 14, 2012 - Lorus Therapeutics Inc. (TSX: LOR) (“Lorus”), a biopharmaceutical company specializing in the discovery, research and development of pharmaceutical products and technologies for the management of cancer, today announced the addition of MD Anderson Cancer Center as a second site in the ongoing Lorus Phase I clinical trial with its first-in-class anticancer drug LOR-253, under the direction of Dr. Jennifer Wheler as the Principal Investigator.
This study, being conducted in patients with solid tumors for whom no effective therapy is available or in patients who were unresponsive to conventional therapy, is already in progress at another leading research institution, Memorial Sloan Kettering Cancer Center in New York, with Dr. Andrea Cercek as Principal Investigator and Dr. Leonard Saltz as Co-Investigator.
These two sites are among the most widely recognized centers for cancer research and clinical oncology trials in the United States.
The study has already successfully completed the accelerated drug dose escalation stage (Stage 1), with further escalation under way in the non-accelerated dose escalation stage (Stage 2) for the purpose of determining the maximal tolerated dose level and recommended Phase II dose. With dosing already at more than 5 times the starting dose level, this is an important point in the trial to expand the investigation to another site for further dose escalation and evaluation of the effects of the drug as a single agent.
The addition of a second site expands patient availability for enrollment now that the study has entered Stage 2. Upon completion of the final dose of this stage, the study will be further expanded to include biopsy-suitable patients for evaluating direct drug effects in the tumors.
LOR-253 is an inducer of the intracellular tumor suppressor factor KLF4 as a principal mechanism of action for its anticancer activity. The MD Anderson Cancer Center is not only the largest oncology clinical trial center in the United States, but also has an ongoing research program on KLF4 as a cancer target.
Lorus’ President and CEO, Dr Aiping Young, commented: “We are delighted to have the opportunity to collaborate with the MD Anderson Cancer Center on our LOR-253 clinical program, with the added benefit of their established expertise on biomarkers for targeted cancer therapy including KLF4”.
About LOR-253
LOR-253 represents a new class of anticancer agent, which we believe may offer a competitive advantage over conventional drugs. This drug candidate has shown selective and potent antitumor activity in preclinical investigations with a variety of human cancers, including colon cancer and non-small cell lung cancer, and has demonstrated an excellent therapeutic window due to its low toxicity. LOR-253 is a first-in-class small molecule that has been optimized to inhibit the novel cancer target Metal-Responsive Transcription Factor 1 (MTF-1). MTF-1 is over-expressed in selective cancer indications, and its down-regulation by LOR-253 results in induction of the novel tumor suppressor Krüppel-like factor 4 (KLF4), leading to the down-regulation of cyclin D1, an important regulator of cell cycle progression and cell proliferation. MTF-1 down-regulation also results in decreased expression of genes involved in the adaptation of tumors to hypoxia (low oxygen content) and angiogenesis. Increased angiogenesis and alterations in the cyclin D1 regulatory pathway have been linked to the development of cancer.
About Lorus
Lorus is a biopharmaceutical company focused on the discovery, research and development of novel therapeutics in cancer. Lorus’ goal is to capitalize on its research, preclinical, clinical and regulatory expertise by developing new drug candidates that can be used, either alone, or in combination with other drugs, to successfully manage cancer. The Company also has expertise in antimicrobial drug discovery. Lorus Therapeutics Inc. is listed on the Toronto Stock Exchange under the symbol LOR.
Forward Looking Statements
This press release may contain forward-looking statements within the meaning of Canadian and U.S. securities laws. Such statements include, but are not limited to, statements relating to: our ability to fund our operations and ongoing and future clinical research programs, our research program plans, our plans to conduct clinical trials, our ability to enroll the necessary patients to complete ongoing clinical trials, the successful and timely completion of clinical studies and the regulatory approval process, our ability to continue as a going concern, , the Company’s plans, objectives, expectations and intentions and other statements including words such as “continue”, “believe”, “plan”, “expect”, “intend”, “will”, “should”, “may”, and other similar expressions. Such statements reflect our current views with respect to future events and are subject to risks and uncertainties and are necessarily based upon a number of estimates and assumptions that, while considered reasonable by us are inherently subject to significant business, economic, competitive, political and social uncertainties and contingencies. Many factors could cause our actual results, performance or achievements to be materially different from any future results, performance, or achievements that may be expressed or implied by such forward-looking statements, including, among others: our ability to continue as a going concern, our ability to obtain the capital required for research and operations, the inherent risks in early stage drug development including demonstrating efficacy, development time/cost and the regulatory approval process; the progress of our clinical trials; our ability to find and enter into agreements with potential partners; our ability to attract and retain key personnel; changing market conditions; and other risks detailed from time-to-time in our ongoing quarterly filings, annual information forms, annual reports and annual filings with Canadian securities regulators and the United States Securities and Exchange Commission.
Should one or more of these risks or uncertainties materialize, or should the assumptions set out in the section entitled “Risk Factors” in our Annual Information Form underlying those forward-looking statements prove incorrect, actual results may vary materially from those described herein. These forward-looking statements are made as of the date of this press release and we do not intend, and do not assume any obligation, to update these forward-looking statements, except as required by law. We cannot assure you that such statements will prove to be accurate as actual results and future events could differ materially from those anticipated in such statements. Investors are cautioned that forward-looking statements are not guarantees of future performance and accordingly investors are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty therein.
Lorus Therapeutics Inc.’s recent press releases are available through the Company’s website at www.lorusthera.com. For Lorus' regulatory filings on SEDAR, please go to www.Sedar.com.
Enquiries:
For further information, please contact:
Grace Tse, 416-798-1200 ext. 380; ir@lorusthera.com
Christine Stewart, 416-644-2020; cstewart@renmarkfinancial.com
Exhibit 99.2
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NEWS RELEASE |
Lorus Therapeutics Announces Issuance of Canadian Patent
for Novel Anticancer Therapy IL-17E
TORONTO, CANADA, June 28, 2012 - Lorus Therapeutics Inc. (TSX: LOR) (“Lorus”), a biopharmaceutical company specializing in the discovery, research and development of pharmaceutical products and technologies for the management of cancer, today announced that the Canadian Intellectual Property Office has issued Lorus’ patent for its cancer immunotherapy agent, IL-17E.
The Canadian patent protects the use of IL-17E to treat cancer, including many different solid tumors such as colon, breast, ovarian, pancreatic, and lung cancers as well as melanoma until 2026. The patent also covers treatment of these cancers with IL-17E in combination with several approved anticancer therapeutics, including Avastin (bevacizumab), Gemzar (gemcitabine), Tarceva (erlotinib), Taxotere (docetaxel), Taxol (paclitaxel) and cisplatin.
“The allowance of our Canadian patent for IL-17E is an important milestone that adds substantial value to our IP portfolio,” said Dr. Aiping Young, Lorus' President and CEO. “We're very pleased with the broad range of cancer types covered by this patent, since this will not only significantly expand the market potential of this unique anticancer agent, but also greatly enhance the partnership potential of this program.”
In addition to the Canadian patent, Lorus has pending patents for anticancer uses of IL-17E in Europe and the United States.
About IL-17E
IL-17E (also known as IL-25) is a recently identified cytokine that plays an important role in inflammation. Lorus has discovered that human IL-17E has potent anticancer properties against a range of solid tumors, including human melanoma, pancreatic, colon, lung, ovarian and breast tumor models with very low toxicity. IL-17E is highly potent and does not require further modification or optimization before proceeding to the formal IND-enabling preclinical studies planned to support advancing to a Phase I clinical trial. Lorus has selected pancreatic cancer and malignant melanoma as the initial lead cancer indications for this agent. An estimated 43,920 new cases of pancreatic cancer will be diagnosed in the US this year and 37,390 Americans will to succumb to the disease, making it the fourth most common cause of cancer deaths in the US. Pancreatic cancer is a difficult-to-treat tumor type with an overall five year survival rate of 4%, the lowest for any cancer. Melanoma is the fifth most common cancer in the US with an estimated 76,250 new cases expected to being diagnosed this year. Approximately 9,180 Americans are expected to die from malignant melanoma in 2012.
About Lorus
Lorus is a biopharmaceutical company focused on the discovery, research and development of novel therapeutics in cancer. Lorus’ goal is to capitalize on its research, preclinical, clinical and regulatory expertise by developing new drug candidates that can be used, either alone, or in combination with other drugs, to successfully manage cancer. The Company also has expertise in antimicrobial drug discovery. Lorus Therapeutics Inc. is listed on the Toronto Stock Exchange under the symbol LOR.
Forward Looking Statements
This press release may contain forward-looking statements within the meaning of Canadian and U.S. securities laws. Such statements include, but are not limited to, statements relating to: our ability to fund future research, our research program plans, our plans to conduct clinical trials, the successful and timely completion of clinical studies and the regulatory approval process, our ability to continue as a going concern, our ability to obtain partners to assist in the further development of our product candidates, the establishment of corporate alliances, the Company’s plans, objectives, expectations and intentions and other statements including words such as “continue”, “believe”, “plan”, “expect”, “intend”, “will”, “should”, “may”, and other similar expressions. Such statements reflect our current views with respect to future events and are subject to risks and uncertainties and are necessarily based upon a number of estimates and assumptions that, while considered reasonable by us are inherently subject to significant business, economic, competitive, political and social uncertainties and contingencies. Many factors could cause our actual results, performance or achievements to be materially different from any future results, performance, or achievements that may be expressed or implied by such forward-looking statements, including, among others: our ability to continue as a going concern, our ability to obtain the capital required for research and operations, the inherent risks in early stage drug development including demonstrating efficacy, development time/cost and the regulatory approval process; the progress of our clinical trials; our ability to find and enter into agreements with potential partners; our ability to attract and retain key personnel; changing market conditions; and other risks detailed from time-to-time in our ongoing quarterly filings, annual information forms, annual reports and annual filings with Canadian securities regulators and the United States Securities and Exchange Commission.
Should one or more of these risks or uncertainties materialize, or should the assumptions set out in the section entitled “Risk Factors” in our Annual Information Form underlying those forward-looking statements prove incorrect, actual results may vary materially from those described herein. These forward-looking statements are made as of the date of this press release and we do not intend, and do not assume any obligation, to update these forward-looking statements, except as required by law. We cannot assure you that such statements will prove to be accurate as actual results and future events could differ materially from those anticipated in such statements. Investors are cautioned that forward-looking statements are not guarantees of future performance and accordingly investors are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty therein.
Lorus Therapeutics Inc.’s recent press releases are available through the Company’s website at www.lorusthera.com. For Lorus' regulatory filings on SEDAR, please go to www.Sedar.com.
Enquiries:
For further information, please contact:
Grace Tse, 416-798-1200 ext. 380; ir@lorusthera.com
Christine Stewart, 416-644-2020; cstewart@renmarkfinancial.com
Exhibit 99.3
![]() |
NEWS RELEASE |
Lorus Therapeutics Reports Results for Fiscal Year 2012
TORONTO, CANADA - August 8, 2012 - Lorus Therapeutics Inc. (TSX: LOR) (“Lorus” or the “Company”) a biopharmaceutical company specializing in the discovery, research and development of pharmaceutical products and technologies for the management of cancer, today reported financial results for the twelve months ended May 31, 2012. Unless specified otherwise, all amounts are in Canadian dollars.
2012 TO DATE HIGHLIGHTS
Corporate Highlights
• Subsequent to year-end in June 2012 the Company completed a private placement whereby Lorus issued 20,625,000 units consisting of one common share and one common share purchase warrant at a price of $0.32 for gross proceeds of $6.6 million. In connection with the private placement the Company paid a cash finders fee equal to 6% of the gross proceeds of the private placement and issued 1,237,500 finder’s warrants (exercisable into units) at an exercise price of $0.32 each. Following the offering the Company repaid all outstanding promissory notes and no longer has any liabilities outside of accounts payable and accruals.
• In August 2011 the Company completed a unit offering of 5,484,000 units at a price of $0.40 per unit, representing gross proceeds of approximately $2.2 million. Each unit is comprised of one common share and one common share purchase warrant.
• In June 2012 the Company received proceeds of $178 thousand on the exercise of 396 thousand warrants related to the August 2011 financing.
Drug Development Highlights
• LOR-253 Program:
• Announced the addition of MD Anderson Cancer Center as a second site in the ongoing Phase I clinical trial with Lorus’ lead small molecule and first-in-class anticancer drug LOR-253, under the direction of Dr. Jennifer Wheler as the Principal Investigator. This study, being conducted in patients with solid tumors for whom no effective therapy is available or in patients who were unresponsive to conventional therapy, is already in progress at another leading research institution, Memorial Sloan Kettering Cancer Center in New York, with Dr. Andrea Cercek as Principal Investigator and Dr. Leonard Saltz as Co-Investigator. These two sites are among the most widely recognized centers for cancer research and clinical oncology trials in the United States.
• The LOR-253 Phase I study successfully completed the accelerated drug dose escalation stage (Stage 1), with further escalation under way in the non-accelerated dose escalation stage (Stage 2) for the purpose of determining the maximum tolerated dose level and recommended Phase II dose. A favorable safety profile has been observed to this point in the trial, since dosing has exceeded 5 times the starting dose level without reaching the maximum tolerated dose.
• Presented new preclinical data for LOR-253 at the American Association for Cancer Research annual meeting supporting the treatment of lung and colon cancers with LOR-253 in combination with a variety of chemotherapy agents. The studies examined the anticancer activities of LOR-253 given in combination with approved anticancer agents at different doses and schedules. The preclinical data showed that initial treatment of non-small cell lung cancer (NSCLC) cells with chemotherapy drugs docetaxel, paclitaxel, or cisplatin, followed by treatment with LOR-253, had significant and synergistic anticancer activity compared to each of the drugs given alone.
• Announced the presentation of positive nonclinical toxicity data for LOR-253 at the Annual Meeting of the American College of Toxicology. The poster presentation detailed the results of nonclinical toxicity and toxicokinetic studies conducted with LOR-253. The studies were part of the formal safety evaluation of LOR-253 to support first-in-man clinical trials in cancer, and to determine the starting dose of LOR-253 in patients. Overall, LOR-253 had a favorable nonclinical toxicology profile in certain animal species and was well tolerated at doses higher than efficacious dose levels established in animal models of human cancers. Of significance, the data show that the effective dose could be potentially increased by a factor of eight to fifteen before observing levels of toxicity.
• Allowed composition of matter patents by the United States Patent and Trademark Office, the Canadian Patent Office and the Australian Patent Office for LOR-253. .
• IL-17E
• Entered into a global license with Genentech in respect of certain patents owned by Genentech for IL-17E. This license allows Lorus to develop IL-17E as a novel and exciting treatment for a large number of cancers. Lorus scientists were the first to discover the anticancer properties of IL-17E and the Company has patents pending for the use of IL-17E in cancer in the major world markets
• The Canadian Intellectual Property Office issued Lorus a patent for its anticancer immunotherapy agent IL-17E, protecting the use of IL-17E to treat cancer, including many different solid tumors such as colon, breast, ovarian, pancreatic, and lung cancers as well as melanoma until 2026. The patent also covers treatment of these cancers with IL-17E in combination with several approved anticancer therapeutics.
• Other Programs:
• Announced promising results obtained from preclinical studies on Lorus’ lead antimicrobial small molecule compound LOR-220. The studies examined the antibacterial activity of LOR-220 against drug sensitive and drug resistant bacteria that had been isolated from patients with bacteremia and other bacterial infections. LOR-220 showed potent antibacterial activity against a panel of 330 clinical isolates of bacteria, including Streptococcus pneumoniae, methicillin-resistant Staphylococcus aureus (MRSA), and Vancomycin-resistant enterococci (VRE) among the so-called “superbugs”. In addition, LOR-220 demonstrated higher antibacterial activity than that of Vancomycin and Linezolid, both of which are antibiotics currently used to treat serious bacterial infections. LOR-220 also significantly improved survival of mice infected with two different species of VRE, which, when left untreated, led to 100% lethality.
“We are pleased with the completion of a significant financing subsequent to the year ended May 31, 2012,” said Dr. Aiping Young, President and CEO of Lorus. “The proceeds from the financing will allow us to capitalize upon the achievements in our LOR-253 development program during the year by bringing the trial to completion as well as to initiate a development program for IL-17E. We look forward to continuing to advance our product platforms in fiscal 2013 and working towards achieving development milestones, partnerships and providing financial stability.”
FINANCIAL RESULTS
Net loss and total comprehensive loss for the year ended May 31, 2012 was $4.6 million ($0.23 per share) compared to $5.0 million ($0.38 per share) in the year ended May 31, 2011. The decrease in net loss and total comprehensive loss of $381 thousand in the year ended May 31, 2012 compared with the prior year is due primarily to a reduction in research and development expenses of $348 thousand in the current year. The decrease in research and development costs is due to reduced program expenditures relating to no further spending on our RNA-Targeted Therapies. In the prior year we incurred costs related to the development of a Phase III clinical trial protocol. The spending on our RNA-Targeted Therapies was partially redirected by higher resources allocated to the development of our small molecule program, including the LOR-253 Phase 1 clinical trial currently underway, as well as the LOR-500 discovery program.
Research and development expenses totaled $2.2 million in the year ended May 31, 2012 compared to $2.5 million during the prior year. Research and development expenses consist of the following:
2012 | 2011 | ||||||
Program costs (see below) | $ | 1,900 | 2,298 | ||||
Deferred share unit costs | 91 | ─ | |||||
Stock based compensation | 146 | 181 | |||||
Depreciation of equipment | 33 | 39 | |||||
$ | 2,170 | 2,518 |
Program costs by program:
2012 | 2011 | ||||||
Small molecule program | $ | 1,900 | 1,672 | ||||
Immunotherapy | ─ | ─ | |||||
RNA-targeted therapies | ─ | 626 | |||||
$ | 1,900 | 2,298 |
The decrease in research and development expenses is attributable to a reduction in program spending to $1.9 million compared with $2.3 million in the prior year and is due to no further spending on our RNA-targeted therapies, compared with $626 thousand in the prior year. Higher resources allocated to the development of our small molecule program offset this reduction, in particular the ongoing Phase I clinical trial for LOR-253 and the LOR-500 discovery program. The reduction in program expenditures is offset by higher deferred share unit costs which represent the fair value of units allocated to research and development expense issued in March 2012. No deferred share units were issued in the year ended May 31, 2011.
General and administrative expenses totaled $2.4 million for the year ended May 31, 2012 compared to $2.4 million in the prior year. General and administrative expenses consisted of the following:
2012 | 2011 | |||||
General and administrative excluding salaries | $ | 1,240 | 1,354 | |||
Salaries | 605 | 747 | ||||
Deferred share unit costs | 213 | ─ | ||||
Stock based compensation | 361 | 302 | ||||
Depreciation of equipment | 11 | 17 | ||||
$ | 2,430 | 2,420 |
General and administrative expenses excluding salaries decreased during the year ended May 31, 2012 compared with the prior year. This decrease is mainly attributable to expenses related to a terminated financing incurred during the year ended May 31, 2011 offset by higher legal costs during the current year. Salary expenses decreased in the year ended May 31, 2012 compared with the prior year due to headcount reductions in the current year. Deferred share unit costs incurred in the current year relate to the fair value of units allocated to general and administrative expense issued in March 2012. No deferred share units were issued in the year ended May 31, 2011.
At May 31, 2012 we had cash and cash equivalents of $320 thousand compared to $911 thousand at May 31, 2011. Subsequent to year-end we completed a private placement raising gross proceeds of $6.6 million providing additional capital for fiscal year 2013. In connection with the private placement the Company paid a cash finder’s fee equal to 6% of the gross proceeds of the private placement. In addition the Company repaid all outstanding promissory notes and no longer has any liabilities outside of accounts payable and accruals.
Management has forecasted that the Company’s current level of cash and cash equivalents, including the $6.6 million investment described above, will be sufficient to execute its current planned expenditures for the next ten to twelve months without further investment. The Company is currently evaluating several future funding alternatives. Management believes that it will complete one of these arrangements in sufficient time to continue to execute its planned expenditures, however, there can be no assurance that the capital will be available as necessary to meet continuing expenditures, or if the capital is available, that it will be on terms acceptable to the Company.
Lorus Therapeutics Inc. | ||||
Consolidated Statements of Loss and Comprehensive Loss | ||||
(amounts in 000's of Canadian dollars, except for per common share data)
Years ended May 31, 2012 and 2011 |
||||
2012 | 2011 | |||
REVENUE | $ ― | $ ― | ||
EXPENSES | ||||
Research and development | 2,170 | 2,518 | ||
General and administrative | 2,430 | 2,420 | ||
Operating expenses | 4,600 | 4,938 | ||
Finance expense | 20 | 71 | ||
Finance income | (6) | (14) | ||
Net finance expense (income) | 14 | 57 | ||
Net loss and total comprehensive loss for the year | 4,614 | 4,995 | ||
Basic and diluted loss per common share | $ 0.23 | $ 0.38 | ||
Weighted average number of common shares | ||||
outstanding used in the calculation of: | ||||
Basic and diluted loss per share | 20,260 | 13,157 |
About Lorus
Lorus is a biopharmaceutical company focused on the discovery, research and development of novel therapeutics in cancer. Lorus’ goal is to capitalize on its research, preclinical, clinical and regulatory expertise by developing new drug candidates that can be used, either alone, or in combination with other drugs, to successfully manage cancer. Through its own discovery efforts and an acquisition and in-licensing program, Lorus is building a portfolio of promising anticancer drugs. Lorus Therapeutics Inc. is listed on the Toronto Stock Exchange under the symbol LOR.
Forward Looking Statements
This press release contains forward-looking statements within the meaning of Canadian and U.S. securities laws. Such statements include, but are not limited to, statements relating to: financings, the establishment of corporate alliances, the Company’s plans, objectives, expectations and intentions and other statements including words such as “continue”, “expect”, “intend”, “will”, “should”, “would”, “may”, and other similar expressions. Such statements reflect our current views with respect to future events and are subject to risks and uncertainties and are necessarily based upon a number of estimates and assumptions that, while considered reasonable by us are inherently subject to significant business, economic, competitive, political and social uncertainties and contingencies. Many factors could cause our actual results, performance or achievements to be materially different from any future results, performance or achievements described in this press release. Such expressed or implied forward looking statements could include, among others: our ability to continue to operate as a going concern; our ability to obtain the capital required for research and operations; the inherent risks in early stage drug development including demonstrating efficacy; development time/cost and the regulatory approval process; the progress of our clinical trials; our ability to find and enter into agreements with potential partners; our ability to attract and retain key personnel; changing market conditions; and other risks detailed from time-to-time in our ongoing quarterly filings, annual information forms, annual reports and annual filings with Canadian securities regulators and the United States Securities and Exchange Commission.
Should one or more of these risks or uncertainties materialize, or should the assumptions set out in the section entitled “Risk Factors” in our filings with Canadian securities regulators and the United States Securities and Exchange Commission underlying those forward-looking statements prove incorrect, actual results may vary materially from those described herein. These forward-looking statements are made as of the date of this press release and we do not intend, and do not assume any obligation, to update these forward-looking statements, except as required by law. We cannot assure you that such statements will prove to be accurate as actual results and future events could differ materially from those anticipated in such statements. Investors are cautioned that forward-looking statements are not guarantees of future performance and accordingly investors are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty therein.
Lorus Therapeutics Inc.’s recent press releases are available through its website at www.lorusthera.com. For Lorus' regulatory filings on SEDAR, please go to www.Sedar.com.
For further information, please contact:
Elizabeth Williams, 416-798-1200 ext. 372; ewilliams@lorusthera.com