0001171843-17-003507.txt : 20170606 0001171843-17-003507.hdr.sgml : 20170606 20170606161513 ACCESSION NUMBER: 0001171843-17-003507 CONFORMED SUBMISSION TYPE: 6-K PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20170606 FILED AS OF DATE: 20170606 DATE AS OF CHANGE: 20170606 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Aptose Biosciences Inc. CENTRAL INDEX KEY: 0000882361 STANDARD INDUSTRIAL CLASSIFICATION: BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836] IRS NUMBER: 000000000 STATE OF INCORPORATION: A6 FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 6-K SEC ACT: 1934 Act SEC FILE NUMBER: 001-32001 FILM NUMBER: 17894313 BUSINESS ADDRESS: STREET 1: 5955 AIRPORT ROAD, SUITE 228 STREET 2: . CITY: MISSISSAUGA STATE: A6 ZIP: L4V 1R9 BUSINESS PHONE: 647-479-9828 MAIL ADDRESS: STREET 1: 5955 AIRPORT ROAD, SUITE 228 CITY: MISSISSAUGA STATE: A6 ZIP: L4V 1R9 FORMER COMPANY: FORMER CONFORMED NAME: Aptose Biosciences Inc., (formerly LORUS THERAPEUTICS INC.) DATE OF NAME CHANGE: 20140905 FORMER COMPANY: FORMER CONFORMED NAME: LORUS THERAPEUTICS INC DATE OF NAME CHANGE: 19990308 FORMER COMPANY: FORMER CONFORMED NAME: IMUTEC PHARMA INC DATE OF NAME CHANGE: 19970113 6-K 1 f6k_060617.htm FORM 6-K EdgarFiling
 

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

Form 6-K

REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934

For the month of June 2017

Commission File Number: 001-32001 

Aptose Biosciences Inc.
(Translation of registrant's name into English)

5955 Airport Road, Suite 228
Mississauga, ON
L4V 1R9
(Address of principal executive office)

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.
Form 20-F [ X ]      Form 40-F [   ]

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1): 

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7): 


On June 6, 2017, the Registrant issued a press release, a copy of which is attached hereto as Exhibit 99.1 and is incorporated herein by reference.

(c) Exhibit 99.1. Press release dated June 6, 2017


SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

      Aptose Biosciences Inc.    
  (Registrant)
   
  
Date: June 6, 2017     /s/ Gregory K. Chow    
  Gregory K. Chow
  Senior Vice President and Chief Financial Officer
  
EX-99.1 2 exh_991.htm PRESS RELEASE EdgarFiling

EXHIBIT 99.1

Aptose Biosciences Announces Results of Annual Meeting of Shareholders

SAN DIEGO and TORONTO, June 06, 2017 (GLOBE NEWSWIRE) -- Aptose Biosciences Inc. (“Aptose” or the “Company”) (NASDAQ:APTO) (TSX:APS), a clinical-stage company developing highly differentiated therapeutics that target the underlying mechanisms of cancer, today announced the voting results from the Company’s annual meeting of shareholders held today, June 6, 2017 (the “Meeting”).

The Company is pleased to announce that all of the nominees listed in the management proxy circular dated April 18, 2017 were elected as directors.  Each of the directors was elected with greater than 94% of the votes cast by shareholders present at the Meeting or represented by proxy. The results of the vote are detailed below:

Nominee Votes For % Votes For Votes Withheld % Votes
        Withheld
Dr. Denis Burger 4,942,137 94.88 266,640 5.12
Dr. Erich Platzer 4,942,126 94.88 266,651 5.12
Dr. William G. Rice 4,939,458 94.83 269,319 5.17
Dr. Bradley Thompson 4,931,745 94.68 277,032 5.32
Dr. Mark D. Vincent 4,943,710 94.91 265,067 5.09
Warren Whitehead 4,944,586 94.93 264,191 5.07

Aptose shareholders also voted to re-appoint KPMG LLP as auditor of the Company.

A total of 26.2% of the issued and outstanding common shares of the Company were represented in person and by proxy at the Meeting.

During the Annual Meeting of Shareholders, the Company also provided a corporate update on CG’806 and APTO-253. Data for CG’806 as a first-in-class pan-FLT3/BTK inhibitor were presented in two poster presentations last month at the 2017 AACR Hematologic Malignancies meeting held in Boston. In a study conducted at The University of Texas MD Anderson Cancer Center, CG’806 demonstrated superior potency against AML cells driven by various mutant forms of FLT3 relative to competitive agents, and achieved complete elimination of AML FLT3-ITD tumors in the absence of toxicity in a murine model. A second poster highlighted studies conducted at Oregon Health & Science University (OHSU) that demonstrated the ability of CG’806 to potently kill primary malignant cells in samples from patients with various hematologic malignancies including AML, CLL and others. The posters can be viewed at the Publications & Presentations section of the Aptose website here.  As noted previously, Aptose has continued formal studies on APTO-253 in an effort to define the root cause of recent manufacturing setbacks related to the intravenous formulation, and to restore the molecule to a state supporting clinical development and potential partnering. APTO-253 inhibits expression of the c-Myc oncogene, which highlights the rationale to develop the molecule as a potential treatment for AML.

Please refer to the Company’s management proxy circular available on SEDAR at www.sedar.com or EDGAR https://www.sec.gov/edgar.shtml for more details on the matters covered at the Meeting.  Final voting results on all matters voted on at the Meeting will also be filed on SEDAR and EDGAR.

About Aptose

Aptose Biosciences is a clinical-stage biotechnology company committed to developing personalized therapies addressing unmet medical needs in oncology. Aptose is advancing new therapeutics focused on novel cellular targets on the leading edge of cancer. The Company's small molecule cancer therapeutics pipeline includes products designed to provide single agent efficacy and to enhance the efficacy of other anti-cancer therapies and regimens without overlapping toxicities. For further information, please visit www.aptose.com. 

 

For further information, please contact:

Aptose Biosciences
Greg Chow, CFO
647-479-9828
gchow@aptose.com

SMP Communications
Susan Pietropaolo
201-923-2049
susan@smpcommunications.com