Exhibit 10.51

November 30, 2012

VIA HAND DELIVERY

Bruce Tomlinson

P.O. Box 5013

Incline Village, NV 89450

Re:Separation Agreement

Dear Bruce:

This letter, upon your signature, will constitute the Separation Agreement (“Agreement”) between you and PDL BioPharma, Inc. and its affiliates (“PDL” or “the Company”), and co-employer TriNet HR Corporation (with the Company/PDL, collectively referred to as “Releasees”) and the terms of your separation from employment with the Company.

1.Resignation Date. You agree that you have resigned from your employment with the Company effective November 30, 2012. Your last day of work is today, November 30, 2012 (the “Resignation Date”). From and after that date, you will no longer represent to anyone that you are still an employee or representative of the Company and you will not say or do anything purporting to bind the Releasees.

2.Effective Date and Rescission. You have up to twenty-one days after you receive this Agreement to review it. You hereby acknowledge that you received this Agreement on November 30, 2012; hence, the Agreement must be signed by you and returned to me no later than the close of business on December 21, 2012. You are advised to consult an attorney of your own choosing (at your own expense) before signing this Agreement. Furthermore, you have up to seven days after you sign this Agreement to revoke it. If you wish to revoke this Agreement after signing it, you may do so by delivering a letter of revocation to me so that I receive it within this seven-day period. If you do not revoke this Agreement, the eighth day after the date you sign it will be the “Effective Date.” Because of the seven-day revocation period, no part of this Agreement will become effective or enforceable until the Effective Date.

3.Salary and Benefits Paid. You acknowledge that you have been paid your earned salary, accrued vacation pay, and all other amounts PDL owes you through the Resignation Date and that the check in the amount of $1,608.17 and the direct deposit made on November 30, 2012, are in full satisfaction of such obligations of PDL. You will receive by separate cover information regarding your rights to health insurance continuation under the terms of COBRA and your retirement benefits. To the extent that you have such rights, nothing in this Agreement will impair those rights. You acknowledge that the only payments and benefits that you are entitled to receive from the Releasees in the future are those specified in this Agreement.

4.Return of Property. You will immediately return to the Company any building key(s), security pass, and other access or identification cards (including business cards) and any Company property that is currently in your possession, custody or control, including any documents, computer equipment (other than the Sony laptop and Apple iPad once we remove all PDL information therefrom), and any information you have about the Company's practices, procedures, finances, trade secrets, customer lists, or product marketing. By no later than November 30, 2012, you will also submit any

expense reports with appropriate receipts for any expenses for which you seek reimbursement from the PDL.

5.Representation Regarding Property. You represent that as of November 30, 2012, you will have returned to the Company all property that belongs to the Company, other than the Sony laptop and Apple iPad, including but not limited to all documents that belong to the Company, and files stored on your computer(s) that contain information belonging to the Company and that after you have done so, all such files and documents have been permanently deleted or destroyed.

6.Severance Payment. In consideration of your acceptance of all the terms of this Agreement, but without otherwise admitting your entitlement to such payments, the Company will pay you as follows:

a.$112,101.88 (one hundred and twelve thousand one hundred and one dollars and eighty eight cents). The Company's payments under this sub-paragraph are contingent upon your irrevocable agreement that these payments are in lieu of and will forever extinguish your right to claim that the Releasees have an obligation to make any further payment to you or on your behalf.

b.Customary payroll deductions shall be made from payments described in 6.a. Payment shall be paid within 10 business days of the “Effective Date” of this Agreement as defined in paragraph 2 above.

c.The Company shall be entitled to recover all or a portion of the amounts provided in subsection 6.a. if the Company in good faith determines that you (i) intentionally or knowingly, through fraud or intentional misconduct, misstated financial information determined necessary for the proper functioning of the Company, (ii) are aware of any significant misstated financial information or other significant inaccuracy with respect to the Company's financial information, whether used internally or disclosed to the public, and have failed to attempt to remedy such misstatement and report same to the current management of the Company, whether or not such misstatement or inaccuracy requires restatement of the Company's public disclosures, or (iii) have violated any of the terms of this Agreement, including any of sections 10, 12 or 13 hereof. In the event that the Company, in its discretion, demands repayment of such amounts under this subsection, you will be obligated to repay such amount in cash within ten (10) days of the Company's written demand. The Company's rights under this subsection are not in lieu of and are not a waiver or release regarding any further or separate legal action for damages or other legal remedies based on fraud, intentional misconduct or gross negligence committed by you during your employment at the Company.

7.Lease. The Company will make commercially reasonable efforts to assume the obligations under your residential lease in Incline Village by December 14, 2012. You will assist the Company in discussions with the landlord of the property. In the event that the Company is unable to assume the obligations under the lease, it will reimburse you for the rent costs through June 30, 2013. In any event, you will vacate the residential property by December 14, 2012.

8.Release. In consideration for the payments and benefits described in Section 6 above, you on your own behalf and on behalf of your heirs, executors, administrators and assigns hereby fully and forever waive, release, discharge and promise never to assert any claims or causes of action, whether or not now known, suspected or unsuspected, against the Releasees or each of its predecessors, successors or past or present subsidiaries, affiliates, branches, representative offices or parents (collectively, including

the Releasees, the “entities”) and the entities' stockholders, directors, officers, employees, consultants, attorneys, agents, assigns, and employee benefit plans with respect to any matter, including (without limitation) any matter related to your employment with the Releasees or the resignation of that employment, including (without limitation) claims to attorney fees or costs, claims of wrongful discharge, constructive discharge, emotional distress, defamation, invasion of privacy, interference with a leave of absence, personal injury, fraud, breach of contract or breach of the covenant of good faith and fair dealing and any claims of discrimination or harassment based on sex, age, race, national origin, disability, or any other basis under Title VII of the Civil Rights Act of 1964, the Fair Labor Standards Act, the Equal Pay Act of 1963, the Civil Rights Act of 1866, the Age Discrimination in Employment Act of 1967, the Americans with Disabilities Act, the Family Medical Leave Act, or any other federal, state, municipal or local law or regulation relating to employment or employment discrimination including but not limited to Nev. Rev. Stat. §§613.310, 613.320, 613.330, 613.333, 613.335 and 613.345 (prohibiting discrimination based on various protected factors), , and including any claims you may have related to your Severance Agreement entered into as of June 11, 2012, or your offer of employment letter dated April 20, 2012, or any other agreement which you have signed in relation to your employment at the Company. You further understand and agree that this waiver includes all claims, known and unknown, suspected and unsuspected, to the greatest extent permitted by applicable law. However, this release covers only claims arising prior to the execution of this Agreement and only those claims that may be waived by applicable law.

9.Promise not to make Claims. You also waive and release and promise never to assert any claims against any of the Releasees or entities, even if you do not believe that you have such claims. You understand and agree that claims or facts in addition to or different from those which are now known or believed by you to exist may hereafter be discovered, but it is your intention by entering into this Agreement to release all claims you have or may have against the Releasees and the entities, their officers, directors, employees, agents, and representatives, whether known or unknown, suspected or unsuspected.

10.Proprietary Information; No Solicitation. You acknowledge that, because of your position with the Company, you have specific knowledge of many types of information which is proprietary to the Company, including, but not limited to, its current and planned technology; its finances, financial planning and financial condition, its current and planned corporate strategies; strategic customers and business partners; and the identity, skills, compensation and interests of its employees. You further agree to the following:

a. You will not, directly or indirectly, solicit, recruit, or induce to leave the employ of or work for the Company any employee, agent, independent contractor or consultant of the Company;

b. You will not, unless required or otherwise permitted by law, disclose to others any proprietary information of the Company including, but not limited to, the Company's current and planned technology; its finances, financial planning and financial condition, its current and planned corporate strategies; strategic customers and business partners; and the identity, skills, compensation and interest of its employees. You agree to keep and treat all such proprietary information as confidential; and

c.You acknowledge and agree (i) that any violation of this Section 10 would cause immediate and irreparable damage to PDL, and (ii) that determining the amount of damage caused to PDL by any such violation would be extremely difficult or impossible. You therefore agree that PDL's remedies at law are inadequate, and you consent to the issuance of injunctive relief, including but not limited to, a temporary restraining order, a preliminary injunction, and a permanent injunction, by a court of appropriate jurisdiction in order to restrain any actual or threatened violation of this Section without limiting any remedy PDL may have at law or equity.

d. You will at all times in the future honor and abide by your obligations under the Employee Proprietary Information and Invention Assignment you signed on April 23, 2012, a copy of which is attached hereto and incorporated as though fully set forth herein.

11.Disputes. To ensure the rapid and economical resolution of disputes that may arise in connection with your employment, you and the Releasees agree that any and all disputes, claims, or causes of action, in law or equity, arising from or relating to the enforcement, breach, performance, or interpretation of this Agreement, your employment, or the resignation of your employment, shall be resolved, to the fullest extent permitted by law, by final, binding and confidential arbitration in Carson City, Nevada conducted by Judicial Arbitration and Mediation Services, Inc. (“JAMS”) or its successor, under the then applicable rules of JAMS. You acknowledge that by agreeing to this arbitration procedure, both you and the Releasees waive the right to resolve any such dispute through a trial by jury or judge or by administrative proceeding. The arbitrator shall: (i) have the authority to compel adequate discovery for the resolution of the dispute and to award such relief as would otherwise be permitted by law; and (ii) issue a written arbitration decision including the arbitrator's essential findings and conclusions and a statement of the award. The Company shall pay all JAMS' arbitration fees in excess of those administrative fees you would be required to pay if the dispute were decided in a court of law. Nothing in this Agreement is intended to prevent either you or the Releasees from obtaining injunctive relief in court to prevent irreparable harm pending the conclusion of any arbitration. Notwithstanding the provisions of this paragraph, any claims by either party arising under the Employee Proprietary Information and Invention Assignment Agreement or involving trade secrets shall be resolved through the courts and not through the arbitration procedure described above. This provision shall supersede all prior agreements between the parties relating to dispute resolution, including mediation or arbitration.

12.Confidentiality of Agreement. In consideration of this Agreement, you also agree to keep confidential and not disclose the terms of this Agreement, the payments being paid under it or the fact of its payment, except that you may disclose this information in confidence to your spouse, domestic partner, attorney, accountant or other professional advisor to whom you must make the disclosure in order for them to render professional services to you. In addition, you are entitled to disclose the terms of this Agreement to federal and state unemployment officials, but only to the extent that such disclosure is necessary for you to receive unemployment benefits. You will instruct them, however, to maintain the confidentiality of this information just as you must.

13.No Disparagement. You agree that you shall not make any negative or disparaging remarks about the Company, its officers, employees, directors, products, services or business practices.

14.Breach. In the event that you breach any of your obligations under this Agreement or as otherwise imposed by law, the Releasees will be entitled to recover all payments paid under the Agreement and to obtain all other relief provided by law or equity and to recover reasonable attorney fees and costs incurred in any litigation, arbitration or other proceeding brought to enforce the terms of this Agreement.

15.References. If contacted by a prospective employer for reference information, the Releasees will confirm only your dates of employment and position held.

16.Entire Agreement; Governing Law. You agree that no promise, inducement or other agreement not expressly contained in this Agreement or referred to in this Agreement, has been made conferring any benefit upon you, and that this Agreement contains the entire agreement between you and the Releasees with respect to its subject matter, including but not limited to the resignation of your

employment. All prior agreements, understandings, representations, oral agreements and writings are expressly superseded hereby and are of no further force and effect, and you expressly agree that you are not relying on any representations that are not contained in this Agreement. This Agreement is entered into and governed by the laws of the State of Nevada.

17.No Admission of Wrongdoing. Nothing contained in this Agreement will constitute or be treated as an admission by you, the Releasees or the entities of liability, any wrongdoing or any violation of law.

18.Contractual Relationship. You acknowledge that any employment or contractual relationship between PDL and you ended on November 30, 2012, and that you have no further employment or contractual relationship except as may arise out of this Agreement and that you waive any right or claim to reinstatement as an employee of PDL or to seek employment in the future with PDL or any Releasee(s).

19.Tax Liability. You agree that you shall be exclusively liable for the payment of all federal and state taxes which may be due as a result of the consideration received from this severance package, and you hereby represent that you shall make payments on such taxes at the time and in the amount required of you. In addition, you agree to defend, indemnify and hold harmless Releasees and each of them from payment of taxes, interest and/or penalties that are required of them by any government agency at any time as the result of payment of the consideration set forth herein.

20.Counterparts; Paragraph Headings; Facsimiles; Modifications. You agree that this Agreement may be executed in counterparts, each of which shall be an original, but all of which together shall constitute one agreement. Paragraph headings are for reference only, and are not to be deemed or construed as limiting or expanding the content of any particular paragraph or provision. Execution of a facsimile copy shall have the same force and effect as execution of an original, and a facsimile signature shall be deemed an original and valid signature. This Agreement may be modified only in a written document signed by you and an officer of the Company.

Very truly yours,

/s/ John McLaughlin

John McLaughlin

Chief Executive Officer

By my signature below, I acknowledge that I have had the opportunity to review this Agreement carefully with an attorney of my choice; that I understand the terms of the Agreement; and that I voluntarily agree to them.

/s/ Bruce Tomlinson

Bruce Tomlinson

Date: /s/ 11/30/2012