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Fair Value Measurements - Summary of Assets and Liabilities Recorded at Fair Value (Details) - USD ($)
$ in Millions
Dec. 31, 2022
Dec. 31, 2021
Assets    
Available-for-sale debt securities $ 2,293 $ 2,497
MYR    
Liabilities:    
Liability for MYR GmbH (“MYR”) contingent consideration 275 317
Other publicly traded equity securities    
Assets    
Total 5,248 5,743
Fair value, recurring    
Assets    
Total 7,600 8,320
Liabilities:    
Total 538 583
Fair value, recurring | Galapagos    
Assets    
Marketable equity securities 736 931
Fair value, recurring | Arcus    
Assets    
Marketable equity securities 286 559
Fair value, recurring | MYR    
Liabilities:    
Liability for MYR GmbH (“MYR”) contingent consideration 275 317
Fair value, recurring | U.S. treasury securities    
Assets    
Available-for-sale debt securities 410 407
Fair value, recurring | U.S. government agencies securities    
Assets    
Available-for-sale debt securities 35 4
Fair value, recurring | Non-U.S. government securities    
Assets    
Available-for-sale debt securities 34 50
Fair value, recurring | Certificates of deposit    
Assets    
Available-for-sale debt securities 54 249
Fair value, recurring | Corporate debt securities    
Assets    
Available-for-sale debt securities 1,427 1,363
Fair value, recurring | Residential mortgage and asset-backed securities    
Assets    
Available-for-sale debt securities 333 424
Fair value, recurring | Money market funds    
Assets    
Marketable equity securities 3,831 3,661
Fair value, recurring | Other publicly traded equity securities    
Assets    
Marketable equity securities 175 331
Fair value, recurring | Deferred compensation plan    
Assets    
Marketable equity securities 220 261
Liabilities:    
Deferred compensation plan 220 261
Fair value, recurring | Foreign currency derivative contracts    
Assets    
Foreign currency derivative contracts 60 80
Liabilities:    
Foreign currency derivative contracts 42 5
Fair value, recurring | Fair value | Deferred compensation plan    
Assets    
Marketable equity securities 220 261
Fair value, recurring | Level 1    
Assets    
Total 5,658 6,150
Liabilities:    
Total 220 261
Fair value, recurring | Level 1 | Galapagos    
Assets    
Marketable equity securities 736 931
Fair value, recurring | Level 1 | Arcus    
Assets    
Marketable equity securities 286 559
Fair value, recurring | Level 1 | MYR    
Liabilities:    
Liability for MYR GmbH (“MYR”) contingent consideration 0 0
Fair value, recurring | Level 1 | U.S. treasury securities    
Assets    
Available-for-sale debt securities 410 407
Fair value, recurring | Level 1 | U.S. government agencies securities    
Assets    
Available-for-sale debt securities 0 0
Fair value, recurring | Level 1 | Non-U.S. government securities    
Assets    
Available-for-sale debt securities 0 0
Fair value, recurring | Level 1 | Certificates of deposit    
Assets    
Available-for-sale debt securities 0 0
Fair value, recurring | Level 1 | Corporate debt securities    
Assets    
Available-for-sale debt securities 0 0
Fair value, recurring | Level 1 | Residential mortgage and asset-backed securities    
Assets    
Available-for-sale debt securities 0 0
Fair value, recurring | Level 1 | Money market funds    
Assets    
Marketable equity securities 3,831 3,661
Fair value, recurring | Level 1 | Other publicly traded equity securities    
Assets    
Marketable equity securities 175 331
Fair value, recurring | Level 1 | Deferred compensation plan    
Assets    
Marketable equity securities 220 261
Liabilities:    
Deferred compensation plan 220 261
Fair value, recurring | Level 1 | Foreign currency derivative contracts    
Assets    
Foreign currency derivative contracts 0 0
Liabilities:    
Foreign currency derivative contracts 0 0
Fair value, recurring | Level 2    
Assets    
Total 1,943 2,170
Liabilities:    
Total 42 5
Fair value, recurring | Level 2 | Galapagos    
Assets    
Marketable equity securities 0 0
Fair value, recurring | Level 2 | Arcus    
Assets    
Marketable equity securities 0 0
Fair value, recurring | Level 2 | MYR    
Liabilities:    
Liability for MYR GmbH (“MYR”) contingent consideration 0 0
Fair value, recurring | Level 2 | U.S. treasury securities    
Assets    
Available-for-sale debt securities 0 0
Fair value, recurring | Level 2 | U.S. government agencies securities    
Assets    
Available-for-sale debt securities 35 4
Fair value, recurring | Level 2 | Non-U.S. government securities    
Assets    
Available-for-sale debt securities 34 50
Fair value, recurring | Level 2 | Certificates of deposit    
Assets    
Available-for-sale debt securities 54 249
Fair value, recurring | Level 2 | Corporate debt securities    
Assets    
Available-for-sale debt securities 1,427 1,363
Fair value, recurring | Level 2 | Residential mortgage and asset-backed securities    
Assets    
Available-for-sale debt securities 333 424
Fair value, recurring | Level 2 | Money market funds    
Assets    
Marketable equity securities 0 0
Fair value, recurring | Level 2 | Other publicly traded equity securities    
Assets    
Marketable equity securities 0 0
Fair value, recurring | Level 2 | Deferred compensation plan    
Assets    
Marketable equity securities 0 0
Liabilities:    
Deferred compensation plan 0 0
Fair value, recurring | Level 2 | Foreign currency derivative contracts    
Assets    
Foreign currency derivative contracts 60 80
Liabilities:    
Foreign currency derivative contracts 42 5
Fair value, recurring | Level 3    
Assets    
Total 0 0
Liabilities:    
Total 275 317
Fair value, recurring | Level 3 | Galapagos    
Assets    
Marketable equity securities 0 0
Fair value, recurring | Level 3 | Arcus    
Assets    
Marketable equity securities 0 0
Fair value, recurring | Level 3 | MYR    
Liabilities:    
Liability for MYR GmbH (“MYR”) contingent consideration 275 317
Fair value, recurring | Level 3 | U.S. treasury securities    
Assets    
Available-for-sale debt securities 0 0
Fair value, recurring | Level 3 | U.S. government agencies securities    
Assets    
Available-for-sale debt securities 0 0
Fair value, recurring | Level 3 | Non-U.S. government securities    
Assets    
Available-for-sale debt securities 0 0
Fair value, recurring | Level 3 | Certificates of deposit    
Assets    
Available-for-sale debt securities 0 0
Fair value, recurring | Level 3 | Corporate debt securities    
Assets    
Available-for-sale debt securities 0 0
Fair value, recurring | Level 3 | Residential mortgage and asset-backed securities    
Assets    
Available-for-sale debt securities 0 0
Fair value, recurring | Level 3 | Money market funds    
Assets    
Marketable equity securities 0 0
Fair value, recurring | Level 3 | Other publicly traded equity securities    
Assets    
Marketable equity securities 0 0
Fair value, recurring | Level 3 | Deferred compensation plan    
Assets    
Marketable equity securities 0 0
Liabilities:    
Deferred compensation plan 0 0
Fair value, recurring | Level 3 | Foreign currency derivative contracts    
Assets    
Foreign currency derivative contracts 0 0
Liabilities:    
Foreign currency derivative contracts $ 0 $ 0