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Income Taxes - Schedule of Difference Between Provision For Income Taxes and Federal Statutory Income Tax Rate to Income Before Provision for Income Taxes (Details)
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Components of Income Tax Expense (Benefit), Continuing Operations [Abstract]      
Federal statutory rate 21.00% 21.00% 21.00%
State taxes, net of federal benefit 4.20% 0.40% 0.60%
Foreign earnings at different rates (10.00%) 2.50% (0.90%)
Research and other credits (6.90%) (1.90%) (1.10%)
US tax on foreign earnings 7.20% 4.30% 2.10%
Deferred tax - intra-entity transfer of intangible assets 0.60% (24.00%) 7.50%
Settlement of tax examinations (10.20%) (2.40%) (1.90%)
Acquired IPR&D and related charges 56.20% 0.00% 0.00%
Changes in valuation allowance 6.70% 0.00% 0.00%
Non-taxable unrealized gain / loss on investment 23.00% (5.00%) 0.00%
Other 2.90% 1.10% 2.70%
Effective tax rate 94.70% (4.00%) 30.00%