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Intangible Assets - Additional Information (Details) - USD ($)
$ in Millions
3 Months Ended 6 Months Ended
Jun. 30, 2016
Jun. 30, 2015
Jun. 30, 2016
Jun. 30, 2015
Mar. 31, 2016
Dec. 31, 2015
Acquired Indefinite-lived Intangible Assets [Line Items]            
Indefinite-lived intangible assets $ 318   $ 318     $ 432
In-process research and development impairment     114 $ 0    
Cost of goods sold            
Acquired Indefinite-lived Intangible Assets [Line Items]            
Amortization of intangible assets 210 $ 207 420 $ 413    
YM Biosciences            
Acquired Indefinite-lived Intangible Assets [Line Items]            
Indefinite-lived intangible assets $ 201   201   $ 201 $ 315
In-process research and development impairment     $ 114