CONSOLIDATED STATEMENTS OF OPERATIONS (USD $) In Thousands, except Per Share data, unless otherwise specified	12 Months Ended
	Dec. 31, 2013	Dec. 31, 2012	Dec. 31, 2011
Revenue:
Net product revenue	$ 25,244	$ 2,012
License revenue	55,838
Total revenue	81,082	2,012
Operating expenses:
Cost of goods sold	4,868	187
Inventory impairment and commitment fee	10,225	0
Research and development	29,677	32,065	24,604
Selling, general and administrative	158,235	109,665	22,472
Non-recurring charges	32,691
Total operating expenses	235,696	141,917	47,076
Loss from operations	(154,614)	(139,905)	(47,076)
Interest and other expense (income):
Interest expense (income), net	19,532	(199)	(240)
Other expense	703
Total interest and other income (expense)	20,235	(199)	(240)
Loss from continuing operations before income taxes	(174,849)	(139,706)	(46,836)
Provision for income taxes	97	27	190
Loss from continuing operations	(174,946)	(139,733)	(47,026)
Income (loss) from discontinued operations, net of tax	490	(148)	886
Net loss	$ (174,456)	$ (139,881)	$ (46,140)
Basic and diluted net loss per share:
Continuing operations (in dollars per share)	$ (1.72)	$ (1.42)	$ (0.56)
Discontinued operations (in dollars per share)	$ 0.00	$ 0.00	$ 0.01
Net loss per share (in dollars per share)	$ (1.72)	$ (1.42)	$ (0.55)
Shares used in per share computation:
Basic and diluted (in shares)	101,174	98,289	84,392