Inventories (Details) (USD $)	Sep. 30, 2011	Dec. 31, 2010
Product Information [Line Items]
Raw materials	$ 77,383,000	$ 90,183,000
Work-in-process	22,201,000	19,051,000
Finished goods	7,761,000	9,395,000
Total inventory	107,345,000	118,629,000
Obsolete material	0	1,400,000
Exenatide [Member]
Product Information [Line Items]
Raw materials	$ 21,200,000	$ 23,300,000