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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
 CTNXzytFswHnrPAA+IjwEDGD4dSOxGmsnOBF8ZcHxsJ3ScETO4/Y12WnUV0I+X/V
 s+qzRD+8SU7arz41Plfm8g==

<SEC-DOCUMENT>0001144204-08-055630.txt : 20081001
<SEC-HEADER>0001144204-08-055630.hdr.sgml : 20081001
<ACCEPTANCE-DATETIME>20081001172319
ACCESSION NUMBER:		0001144204-08-055630
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20080929
FILED AS OF DATE:		20081001
DATE AS OF CHANGE:		20081001

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MISONIX INC
		CENTRAL INDEX KEY:			0000880432
		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY APPARATUS & FURNITURE [3821]
		IRS NUMBER:				112148932
		STATE OF INCORPORATION:			NY
		FISCAL YEAR END:			0630

	BUSINESS ADDRESS:	
		STREET 1:		1938 NEW HIGHWAY
		CITY:			FARMINGDALE
		STATE:			NY
		ZIP:			11747
		BUSINESS PHONE:		5166949555

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	MEDSONIC INC
		DATE OF NAME CHANGE:	19930328

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			MCMANUS MICHAEL A JR
		CENTRAL INDEX KEY:			0001051997

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-10986
		FILM NUMBER:		081100687

	BUSINESS ADDRESS:	
		STREET 1:		C/O AMERICAN HOME MORTGAGE HOLDINGS INC
		STREET 2:		520 BROADHOLLOW ROAD
		CITY:			MELVILLE
		STATE:			NY
		ZIP:			11747
		BUSINESS PHONE:		7182797760

	MAIL ADDRESS:	
		STREET 1:		241-02 NORTHERN BLVD
		CITY:			DOUGLASTON
		STATE:			NY
		ZIP:			11362
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>v127567_ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2008-09-29</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000880432</issuerCik>
        <issuerName>MISONIX INC</issuerName>
        <issuerTradingSymbol>MSON</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001051997</rptOwnerCik>
            <rptOwnerName>MCMANUS MICHAEL A JR</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>100 WHITE PLAINS ROAD</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>BRONXVILLE</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10708</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>President, CEO</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock, par value $.01</value>
            </securityTitle>
            <transactionDate>
                <value>2008-09-29</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>P</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>10000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>1.84</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>193251</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <ownerSignature>
        <signatureName>/s/ Michael A. McManus</signatureName>
        <signatureDate>2008-10-01</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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