Consolidated Statements of Cash Flows (Unaudited) - USD ($)	9 Months Ended
	Sep. 30, 2018	Sep. 30, 2017
Cash flows from operating activities
Net loss	$ (8,409,213)	$ (7,145,868)
Adjustments to reconcile net loss to net cash used in operating activities:
Stock option compensation expense	984,157	801,716
Common stock issued for interest and fees for services from consultants	1,162,919	759,988
Interest expense related to amortization of the discount on convertible notes payable	2,212,612	2,315,396
Debt conversion expense	275,534
Loss on extinguishment of debt	578,312
Deferred offering cost expense	19,059	464
Bad debt expense	1,000	2,500
Depreciation and amortization expense	36,302	21,086
Changes in assets and liabilities:
Accounts receivable	(19,006)	(48,149)
Inventory	7,779	(4,838)
Prepaid expenses and other current assets	(42,856)	(42,734)
Accounts payable and accrued expenses	142,113	345,844
Officer bonus		(80,000)
Net cash used in operating activities	(3,051,288)	(3,074,645)
Cash flows from investing activities
Equipment and Leasehold improvements	(42,656)	(9,000)
Net cash used in investing activities	(42,656)	(9,000)
Cash flows from financing activities
Proceeds from convertible notes and notes payable	880,000	1,266,200
Proceeds from line of credit	430,000	250,000
Proceeds from sale of Clyra shares		750,000
Proceeds from notes payable conversion inducement	356,781
Proceeds from warrant exercise-price reduction	148,854
Proceeds from sale of stock to Lincoln Park Capital	826,279	22,500
Purchase of Clyra shares		(40,000)
Proceeds from exercise of warrants		153,000
Net cash provided by financing activities	2,641,914	2,401,700
Effect of foreign currency translation	(4,885)	23,743
Net change in cash and cash equivalents	(456,915)	(658,202)
Cash and cash equivalents at beginning of period	990,457	1,910,153
Cash and cash equivalents at end of period	533,542	1,251,951
Supplemental disclosures of cash flow information
Interest	5,489	6,731
Income taxes	5,719	5,350
Non-cash investing and financing activities:
Fair value of warrants issued in conjunction with convertible notes payable	570,462	1,067,629
Deemed dividend	297,439	299,111
Cumulative effect of change in accounting		663,560
Common Stock Issued for Financing Commitments [Member]
Non-cash investing and financing activities:
Fair value of stock issued	85,073
Conversion of Convertible Notes Issued with Original Issue Discount [Member]
Non-cash investing and financing activities:
Conversion of debt	10,000
Stock Issued for Line of Credit [Member]
Non-cash investing and financing activities:
Fair value of stock issued		250,000
Stock Issued for Financing Fee, Lincoln Park [Member]
Non-cash investing and financing activities:
Fair value of stock issued		206,000
Stock Issued for Equipment [Member]
Non-cash investing and financing activities:
Fair value of stock issued	10,000
Stock Issued to CEO [Member]
Non-cash investing and financing activities:
Fair value of stock issued		1,005
Stock Issued for Exercise of Stock Options [Member]
Non-cash investing and financing activities:
Fair value of stock issued		1,677
Issuance of Clyra Shares [Member]
Non-cash investing and financing activities:
Fair value of stock issued		411,455
Conversion of Convertible Notes Payable into Common Stock [Member]
Non-cash investing and financing activities:
Fair value of stock issued	$ 5,930,143	$ 836,250