Note 1 - Business and Liquidity (Details Textual) - USD ($)	3 Months Ended		9 Months Ended
	Sep. 30, 2018	Sep. 30, 2017	Sep. 30, 2018	Sep. 30, 2017	Dec. 31, 2017	Dec. 31, 2016
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total	$ (2,379,735)	$ (2,246,126)	$ (8,409,213)	$ (7,145,868)
Net Cash Provided by (Used in) Operating Activities, Total			(3,051,288)	(3,074,645)
Working Capital	1,075,985		1,075,985
Assets, Current, Total	752,328		752,328		$ 1,158,843
Retained Earnings (Accumulated Deficit), Ending Balance	(109,591,476)		(109,591,476)		(101,204,846)
Cash and Cash Equivalents, at Carrying Value, Ending Balance	533,542	1,251,951	533,542	1,251,951	$ 990,457	$ 1,910,153
Revenue from Contract with Customer, Including Assessed Tax	$ 277,026	$ 172,045	$ 866,793	$ 318,040