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Consolidated Statements of Cash Flows (Unaudited) - USD ($)
3 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Cash flows from operating activities    
Net loss $ (2,429,568) $ (2,325,676)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock option compensation expense 320,090 280,288
Common stock issued for interest and fees for services from consultants 361,118 261,409
Interest expense related to amortization of the discount on convertible notes payable 635,297 771,124
Deferred offering cost expense 3,688
Bad debt expense 15,000
Depreciation and amortization expense 10,323 7,924
Changes in assets and liabilities:    
Accounts receivable (7,897) (9,442)
Inventories (2,832) 9,818
Prepaid expenses and other current assets (12,745) (143,293)
Accounts payable and accrued expenses 126,895 36,596
Officer bonus (80,000)
Net cash used in operating activities (995,631) (1,176,252)
Cash flows from investing activities    
Leasehold improvements (18,753)
Net cash used in investing activities (18,753)
Cash flows from financing activities    
Proceeds from line of credit 390,000 175,000
Proceeds from convertible notes 380,000 125,000
Proceeds from sale of stock to Lincoln Park Capital 168,220
Proceeds from exercise of warrants 153,000
Net cash provided by financing activities 938,220 453,000
Effect of foreign currency translation 7,649 (11,376)
Net change in cash and cash equivalents (68,515) (734,628)
Cash and cash equivalents at beginning of period 990,457 1,910,153
Cash and cash equivalents at end of period 921,942 1,175,525
Supplemental disclosures of cash flow information    
Interest
Income taxes 5,350
Non-cash investing and financing activities:    
Conversion of debt 141,763
Fair value of warrants issued in conjunction with convertible notes payable 281,751 125,000
Deemed dividend 297,439
Common Stock Issued for Settlement of Accounts Payable and Interest [Member]    
Non-cash investing and financing activities:    
Settlement of accounts payable and interest in shares of common stock 261,409
Conversion of Convertible Notes Payable into Common Stock [Member]    
Non-cash investing and financing activities:    
Fair value of stock issued 400,000
Stock Issued for Financing Fee [Member]    
Non-cash investing and financing activities:    
Fair value of stock issued $ 85,073