Note 1 - Business and Liquidity (Details Textual) - USD ($)	3 Months Ended
	Mar. 31, 2018	Mar. 31, 2017	Dec. 31, 2017	Dec. 31, 2016
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total	$ (2,429,568)	$ (2,325,676)
Net Cash Provided by (Used in) Operating Activities, Total	(995,631)	(1,176,252)
Working Capital	(3,938,814)
Assets, Current, Total	1,113,802		$ 1,158,843
Retained Earnings (Accumulated Deficit), Ending Balance	(103,825,209)		(101,204,846)
Cash and Cash Equivalents, at Carrying Value, Ending Balance	921,942	1,175,525	$ 990,457	$ 1,910,153
Revenue from Contract with Customer, Including Assessed Tax	$ 263,029	$ 46,017