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Note 5 - Share-based Compensation - Stock Options Issued Outside of the 2007 Equity Incentive Plan (Details) - Outside of the 2007 Plan [Member]
9 Months Ended
Sep. 30, 2017
$ / shares
shares
Sep. 30, 2016
$ / shares
shares
Dec. 31, 2016
$ / shares
Dec. 31, 2015
$ / shares
Options outstanding, Balance (in shares) | shares 20,148,766 19,394,975    
Weighted average price per share, Balance (in dollars per share) $ 0.51 $ 0.41 $ 0.40 $ 0.40
Options outstanding, granted (in shares) | shares 6,828,872 484,077    
Weighted average price per share, granted (in dollars per share) $ 0.46 $ 0.38    
Options outstanding, exercised (in shares) | shares 3,866,630 (60,000)    
Exercised, exercise price per share (in dollars per share) $ 0.18 $ 0.25    
Weighted average price per share, exercised (in dollars per share) $ 0.18 $ 0.25    
Options outstanding, Balance (in shares) | shares 19,244,379 19,819,052    
Options outstanding, expired (in shares) | shares (3,866,629)      
Exercise price per share,Expired (in dollars per share) $ 0.18      
Weighted average price per share, expired (in dollars per share) $ 0.18      
Cashless exercise of stock options (in shares) | shares (3,866,630) 60,000    
Minimum [Member]        
Exercise price per share, Balance (in dollars per share) $ 0.18 $ 0.18 0.18 0.18
Exercise price per share, granted (in dollars per share) 0.43 0.33    
Exercised, exercise price per share (in dollars per share)      
Maximum [Member]        
Exercise price per share, Balance (in dollars per share) 1 1 $ 1 $ 1
Exercise price per share, granted (in dollars per share) 0.67 $ 0.45    
Exercised, exercise price per share (in dollars per share)