Note 1 - Business and Organization (Details Textual)	3 Months Ended		9 Months Ended
	Sep. 30, 2017 USD ($)	Sep. 30, 2016 USD ($)	Sep. 30, 2017 USD ($)	Sep. 30, 2016 USD ($)	Aug. 04, 2017	Dec. 31, 2016 USD ($)	Dec. 31, 2015 USD ($)
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest	$ (2,246,126)	$ (2,484,103)	$ (7,145,868)	$ (5,796,831)
Net Cash Provided by (Used in) Operating Activities			(3,074,645)	(2,799,096)
Working Capital	(2,165,714)		(2,165,714)
Assets, Current	1,446,501		1,446,501			$ 2,016,682
Retained Earnings (Accumulated Deficit)	(98,862,024)		(98,862,024)			(91,915,426)
Cash and Cash Equivalents, at Carrying Value	1,251,951	1,731,946	1,251,951	1,731,946		$ 1,910,153	$ 1,763,114
Cash and Cash Equivalents, Period Increase (Decrease)			(658,202)	(31,168)
Revenue, Net	172,045	$ 162,321	318,040	$ 215,249
Long-term Debt, Gross	6,360,618		6,360,618
Convertible Debt	50,000		50,000
Accounts Payable and Accrued Liabilities	$ 455,547		$ 455,547
Number of Wholly-Owned Subsidiaries	7		7
Clyra [Member]
Noncontrolling Interest, Ownership Percentage by Parent	46.30%		46.30%		46.30%