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Note 3 - Convertible Notes Payable and Lines of Credit (Details Textual) - USD ($)
1 Months Ended 3 Months Ended 6 Months Ended
May 24, 2017
Jan. 13, 2017
Dec. 30, 2016
Dec. 27, 2016
Sep. 17, 2016
Jul. 08, 2016
Jun. 06, 2016
May 15, 2017
Jun. 30, 2017
Mar. 31, 2017
Jun. 30, 2016
Jun. 30, 2017
Jun. 30, 2016
Dec. 31, 2016
Share Price     $ 0.83 $ 0.86 $ 0.70                  
Interest Expense, Debt                 $ 1,119,273   $ 478,525 $ 2,072,829 $ 884,850  
Proceeds from Lines of Credit             $ 300,000              
Line of Credit Facility, Interest Rate During Period             18.00%              
Debt Conversion, Original Debt, Amount                       243,824 183,159  
Line of Credit, Current                 $ 50,000     $ 50,000   $ 50,000
Winter 2016 Unit Offering [Member]                            
Class of Warrant or Right, Exercise Period       30 days                    
Class of Warrant or Right, Exercise Period Condition, Number of Trading Days Common Stock Closes at or above 2 Times the Exercise Price       10 days                    
Proceeds from Issuance of Units                   $ 292,000        
Units Issued During Period, Value, New Issues       $ 600,000                    
Debt Instrument, Convertible, Conversion Price       $ 0.57                    
Class of Warrant or Right, Number of Securities Called by Warrants or Rights                   512,281        
Class of Warrant or Right, Exercise Price of Warrants or Rights       $ 0.70                    
Debt Instrument, Interest Rate, Stated Percentage       12.00%                    
Number of Trading Days Prior to Interest Payment Due Date if Paid by Issuance of Common Stock       20 days                    
Debt Conversion before Maturity, Number of Trading Days Common Stock Closes at or above 3 Times the Unit Price       10 days                    
Class of Warrant or Right, Number of Securities Called by Each Warrant or Right       1                    
Winter 2016 Unit Offering [Member] | Three accredited Investors [Member]                            
Proceeds from Issuance of Units                   $ 125,000        
Class of Warrant or Right, Number of Securities Called by Warrants or Rights                   219,298        
Clyra Medical Technology Inc [Member] | Sanatio [Member]                            
Line of Credit Facility, Maximum Borrowing Capacity                   $ 250,000        
Original Issue Discount, Percentage                   5.00%        
Proceeds from Lines of Credit               $ 75,000   $ 175,000        
Debt Instrument, Interest Rate, Stated Percentage                   10.00%        
Clyra Medical Technology Inc [Member]                            
Subsidiary, Parent Ownership Interest                   54.00%        
The 2015 Unit Offering [Member]                            
Debt Instrument, Convertible, Conversion Price                        
Class of Warrant or Right, Exercise Price of Warrants or Rights                        
Proceeds from Convertible Debt                         $ 535,000  
Debt Instrument, Interest Rate, Stated Percentage                     12.00%   12.00%  
Warrants Issued Concurrently With One Year Convertible Note [Member]                            
Class of Warrant or Right, Number of Securities Called by Warrants or Rights     400,000     400,000                
Class of Warrant or Right, Exercise Price of Warrants or Rights $ 0.42   $ 0.75     $ 0.65                
Class of Warrant or Right, Expiration Term     5 years     5 years                
Warrant Issued in Exchange of Cancelled Line of Credit [Member]                            
Class of Warrant or Right, Number of Securities Called by Warrants or Rights         515,583                  
Class of Warrant or Right, Exercise Price of Warrants or Rights         $ 0.70                  
Warrants Issued Concurrently to the Summer 2017 Unit Offering [Member]                            
Class of Warrant or Right, Exercise Period 30 days                          
Class of Warrant or Right, Exercise Period Condition, Number of Trading Days Common Stock Closes at or above 2 Times the Exercise Price 10 days                          
Class of Warrant or Right, Exercise Price of Warrants or Rights $ 0.65                          
Class of Warrant or Right, Number of Securities Called by Each Warrant or Right 1                          
One Year Convertible Notes [Member]                            
Debt Instrument, Convertible, Conversion Price     $ 0.57     $ 0.45               $ 0.57
Debt Conversion, Original Debt, Amount   $ 280,000                        
Debt Conversion, Converted Instrument, Shares Issued   640,889                        
Proceeds from Convertible Debt     $ 250,000     $ 250,000                
Debt Instrument, Face Amount     $ 280,000     $ 280,000                
Debt Instrument, Interest Rate, Stated Percentage     3.00%     3.00%                
Summer 2017 Unit Offering [Member]                            
Proceeds from Issuance of Private Placement $ 1,500,000                          
Debt Instrument, Convertible, Conversion Price $ 0.42                          
Debt Instrument, Interest Rate, Stated Percentage 12.00%                          
Number of Trading Days Prior to Interest Payment Due Date if Paid by Issuance of Common Stock 20 days                          
Debt Conversion before Maturity, Number of Trading Days Common Stock Closes at or above 3 Times the Unit Price 10 days                          
Conversion of Line of Credit to 2015 Unit Offering [Member]                            
Debt Conversion, Original Debt, Accrued Interest Amount         $ 33,571                  
Debt Instrument, Convertible, Conversion Price         $ 0.55                  
Debt Conversion, Original Debt, Amount         $ 250,000                  
Promissory Notes Issued in 2015 Unit Offering and Accrued Interest Into Common Stock [Member]                            
Debt Conversion, Original Debt, Amount                       $ 250,000    
Debt Conversion, Converted Instrument, Shares Issued                       406,789    
Line of Credit [Member]                            
Debt Instrument, Term                       270 days