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Note 1 - Business and Organization (Details Textual) - USD ($)
1 Months Ended 3 Months Ended 6 Months Ended
Aug. 14, 2017
Jun. 30, 2017
Jun. 30, 2016
Jun. 30, 2017
Jun. 30, 2016
Dec. 31, 2016
Dec. 31, 2015
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest   $ (2,517,794) $ (1,668,335) $ (4,577,870) $ (3,312,728)    
Net Cash Provided by (Used in) Operating Activities, Continuing Operations       (2,048,628) (1,693,661)    
Working Capital   (3,175,349)   (3,175,349)      
Assets, Current   561,346   561,346   $ 2,016,682  
Retained Earnings (Accumulated Deficit)   (96,256,129)   (96,256,129)   (91,915,426)  
Cash and Cash Equivalents, at Carrying Value   433,539 $ 889,029 433,539 889,029 $ 1,910,153 $ 1,763,114
Cash and Cash Equivalents, Period Increase (Decrease)       (1,476,614) $ (874,085)    
Long-term Debt, Gross   5,805,668   5,805,668      
Convertible Debt   4,830,097   4,830,097      
Accounts Payable and Accrued Liabilities   $ 344,438   $ 344,438      
Subsequent Event [Member]              
Proceeds from Issuance of Private Placement $ 800,000