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Note 5 - Stockholders' Equity - Stock Options Issued Outside of the 2007 Equity Incentive Plan by Exercise Price Range (Details) - $ / shares
12 Months Ended
Dec. 31, 2016
Mar. 31, 2017
Mar. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Options Outstanding (in shares) 30,065,352        
Outside of the 2007 Plan [Member]          
Options Outstanding (in shares) 20,148,766 20,732,292 19,658,498 19,394,975 17,965,291
Weighted Average Exercise Price (in dollars per share) $ 0.40        
Weighted Average Remaining Contractual Life (Year) 4 years        
Currently Exercisable, Number Of Shares (in shares) 19,998,766        
Currently Exercisable, Weighted Average Exercise Price (in dollars per share) $ 0.40        
Exercise Price Range, Lower Limit (in dollars per share) 0.18        
Exercise Price Range, Upper Limit (in dollars per share) $ 1        
Outside of the 2007 Plan [Member] | Exercise Price Range 1 [Member]          
Options Outstanding (in shares) 7,733,259        
Weighted Average Exercise Price (in dollars per share) $ 0.18        
Weighted Average Remaining Contractual Life (Year) 91 days        
Currently Exercisable, Number Of Shares (in shares) 7,733,259        
Currently Exercisable, Weighted Average Exercise Price (in dollars per share) $ 0.18        
Outside of the 2007 Plan [Member] | Exercise Price Range 2 [Member]          
Options Outstanding (in shares) 2,400,000        
Weighted Average Exercise Price (in dollars per share) $ 0.99        
Weighted Average Remaining Contractual Life (Year) 91 days        
Currently Exercisable, Number Of Shares (in shares) 2,400,000        
Currently Exercisable, Weighted Average Exercise Price (in dollars per share) $ 0.99        
Outside of the 2007 Plan [Member] | Exercise Price Range 3 [Member]          
Options Outstanding (in shares) 691,975        
Weighted Average Exercise Price (in dollars per share) $ 0.55        
Weighted Average Remaining Contractual Life (Year) 2 years        
Currently Exercisable, Number Of Shares (in shares) 691,975        
Currently Exercisable, Weighted Average Exercise Price (in dollars per share) $ 0.55        
Outside of the 2007 Plan [Member] | Exercise Price Range 4 [Member]          
Options Outstanding (in shares) 800,000        
Weighted Average Exercise Price (in dollars per share) $ 1        
Weighted Average Remaining Contractual Life (Year) 5 years        
Currently Exercisable, Number Of Shares (in shares) 800,000        
Currently Exercisable, Weighted Average Exercise Price (in dollars per share) $ 1        
Outside of the 2007 Plan [Member] | Exercise Price Range 5 [Member]          
Options Outstanding (in shares) 168,750        
Weighted Average Exercise Price (in dollars per share) $ 0.40        
Weighted Average Remaining Contractual Life (Year) 6 years        
Currently Exercisable, Number Of Shares (in shares) 168,750        
Currently Exercisable, Weighted Average Exercise Price (in dollars per share) $ 0.40        
Outside of the 2007 Plan [Member] | Exercise Price Range 6 [Member]          
Options Outstanding (in shares) 1,497,986        
Weighted Average Exercise Price (in dollars per share) $ 0.30        
Weighted Average Remaining Contractual Life (Year) 6 years        
Currently Exercisable, Number Of Shares (in shares) 1,497,986        
Currently Exercisable, Weighted Average Exercise Price (in dollars per share) $ 0.30        
Outside of the 2007 Plan [Member] | Exercise Price Range 7 [Member]          
Options Outstanding (in shares) 3,122,093        
Weighted Average Exercise Price (in dollars per share) $ 0.32        
Weighted Average Remaining Contractual Life (Year) 7 years        
Currently Exercisable, Number Of Shares (in shares) 3,122,093        
Currently Exercisable, Weighted Average Exercise Price (in dollars per share) $ 0.32        
Exercise Price Range, Lower Limit (in dollars per share) 0.25        
Exercise Price Range, Upper Limit (in dollars per share) $ 0.65        
Outside of the 2007 Plan [Member] | Exercise Price Range 8 [Member]          
Options Outstanding (in shares) 2,120,947        
Weighted Average Exercise Price (in dollars per share) $ 0.37        
Weighted Average Remaining Contractual Life (Year) 8 years        
Currently Exercisable, Number Of Shares (in shares) 2,120,947        
Currently Exercisable, Weighted Average Exercise Price (in dollars per share) $ 0.37        
Exercise Price Range, Lower Limit (in dollars per share) 0.33        
Exercise Price Range, Upper Limit (in dollars per share) $ 0.47        
Outside of the 2007 Plan [Member] | Exercise Price Range 9 [Member]          
Options Outstanding (in shares) 1,388,166        
Weighted Average Exercise Price (in dollars per share) $ 0.47        
Weighted Average Remaining Contractual Life (Year) 9 years        
Currently Exercisable, Number Of Shares (in shares) 1,238,116        
Currently Exercisable, Weighted Average Exercise Price (in dollars per share) $ 0.47        
Exercise Price Range, Lower Limit (in dollars per share) 0.33        
Exercise Price Range, Upper Limit (in dollars per share) $ 0.65        
Outside of the 2007 Plan [Member] | Exercise Price Range 10 [Member]          
Options Outstanding (in shares) 225,641        
Weighted Average Exercise Price (in dollars per share) $ 0.76        
Weighted Average Remaining Contractual Life (Year) 10 years        
Currently Exercisable, Number Of Shares (in shares) 225,641        
Currently Exercisable, Weighted Average Exercise Price (in dollars per share) $ 0.76        
Exercise Price Range, Lower Limit (in dollars per share) 0.60        
Exercise Price Range, Upper Limit (in dollars per share) $ 0.83