Note 1 - Business and Organization (Details Textual) - USD ($)	3 Months Ended
	Mar. 31, 2017	Mar. 31, 2016	Dec. 31, 2016	Dec. 31, 2015
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest	$ (2,060,076)	$ (1,644,393)
Net Cash Provided by (Used in) Operating Activities	(1,176,252)
Working Capital	713,172
Assets, Current	1,409,971		$ 2,016,682
Retained Earnings (Accumulated Deficit)	(93,912,246)		(91,915,426)
Cash and Cash Equivalents, at Carrying Value	1,175,525	1,022,290	$ 1,910,153	$ 1,763,114
Revenues	46,017
Cash and Cash Equivalents, Period Increase (Decrease)	(734,628)	$ (740,824)
Long-term Debt, Gross	5,760,668
Convertible Debt	5,430,668
Accounts Payable and Accrued Liabilities	$ 236,699