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Note 9 - Stock-based Compensation and Other Employee Benefit Plans - Stock Options Issued Outside of the 2007 Equity Incentive Plan (Details) - $ / shares
12 Months Ended
Dec. 31, 2015
Sep. 30, 2016
Sep. 30, 2015
Dec. 31, 2014
Weighted Average Exercise Price (in dollars per share) $ 1.06      
Weighted Average Remaining Contractual Life (Year) 2 years      
Options, currently exercisable (in shares) 525,000      
Weighted average exercise price, currently exercisable (in dollars per share) $ 1.06      
Exercise Price, Lower Limit (in dollars per share) 0.40      
Exercise Price, Upper Limit (in dollars per share) $ 1.89      
Outside of the 2007 Plan [Member]        
Options Outstanding (in shares) 19,394,975 20,241,948 19,212,474 17,965,291
Weighted Average Exercise Price (in dollars per share) $ 0.40      
Weighted Average Remaining Contractual Life (Year) 8 years      
Options, currently exercisable (in shares) 19,068,303      
Weighted average exercise price, currently exercisable (in dollars per share) $ 0.40      
Exercise Price, Lower Limit (in dollars per share) 0.18      
Exercise Price, Upper Limit (in dollars per share) $ 1      
Outside of the 2007 Plan [Member] | Exercise Price Range 1 [Member]        
Options Outstanding (in shares) 7,733,259      
Weighted Average Exercise Price (in dollars per share) $ 0.18      
Weighted Average Remaining Contractual Life (Year) 1 year      
Options, currently exercisable (in shares) 7,733,259      
Weighted average exercise price, currently exercisable (in dollars per share) $ 0.18      
Outside of the 2007 Plan [Member] | Exercise Price Range 2 [Member]        
Options Outstanding (in shares) 2,400,000      
Weighted Average Exercise Price (in dollars per share) $ 0.99      
Weighted Average Remaining Contractual Life (Year) 1 year      
Options, currently exercisable (in shares) 2,400,000      
Weighted average exercise price, currently exercisable (in dollars per share) $ 0.99      
Outside of the 2007 Plan [Member] | Exercise Price Range 3 [Member]        
Options Outstanding (in shares) 691,975      
Weighted Average Exercise Price (in dollars per share) $ 0.55      
Weighted Average Remaining Contractual Life (Year) 3 years      
Options, currently exercisable (in shares) 691,975      
Weighted average exercise price, currently exercisable (in dollars per share) $ 0.55      
Outside of the 2007 Plan [Member] | Exercise Price Range 4 [Member]        
Options Outstanding (in shares) 800,000      
Weighted Average Exercise Price (in dollars per share) $ 1      
Weighted Average Remaining Contractual Life (Year) 6 years      
Options, currently exercisable (in shares) 483,333      
Weighted average exercise price, currently exercisable (in dollars per share) $ 1      
Outside of the 2007 Plan [Member] | Exercise Price Range 5 [Member]        
Options Outstanding (in shares) 168,750      
Weighted Average Exercise Price (in dollars per share) $ 0.40      
Weighted Average Remaining Contractual Life (Year) 7 years      
Options, currently exercisable (in shares) 168,750      
Weighted average exercise price, currently exercisable (in dollars per share) $ 0.40      
Outside of the 2007 Plan [Member] | Exercise Price Range 6 [Member]        
Options Outstanding (in shares) 1,456,110      
Weighted Average Exercise Price (in dollars per share) $ 0.30      
Weighted Average Remaining Contractual Life (Year) 7 years      
Options, currently exercisable (in shares) 1,456,110      
Weighted average exercise price, currently exercisable (in dollars per share) $ 0.30      
Outside of the 2007 Plan [Member] | Exercise Price Range 7 [Member]        
Options Outstanding (in shares) 3,288,246      
Weighted Average Exercise Price (in dollars per share) $ 0.28      
Weighted Average Remaining Contractual Life (Year) 8 years      
Options, currently exercisable (in shares) 3,288,246      
Weighted average exercise price, currently exercisable (in dollars per share) $ 0.28      
Exercise Price, Lower Limit (in dollars per share) 0.25      
Exercise Price, Upper Limit (in dollars per share) $ 0.65      
Outside of the 2007 Plan [Member] | Exercise Price Range 8 [Member]        
Options Outstanding (in shares) 1,833,518      
Weighted Average Exercise Price (in dollars per share) $ 0.40      
Weighted Average Remaining Contractual Life (Year) 9 years      
Options, currently exercisable (in shares) 1,833,518      
Weighted average exercise price, currently exercisable (in dollars per share) $ 0.40      
Exercise Price, Lower Limit (in dollars per share) 0.33      
Exercise Price, Upper Limit (in dollars per share) $ 0.47      
Outside of the 2007 Plan [Member] | Exercise Price Range 9 [Member]        
Options Outstanding (in shares) 1,023,112      
Weighted Average Exercise Price (in dollars per share) $ 0.40      
Weighted Average Remaining Contractual Life (Year) 10 years      
Options, currently exercisable (in shares) 1,013,112      
Weighted average exercise price, currently exercisable (in dollars per share) $ 0.40      
Exercise Price, Lower Limit (in dollars per share) 0.35      
Exercise Price, Upper Limit (in dollars per share) $ 0.65