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Note 12 - Summary of Stock Options (Tables)
9 Months Ended
Sep. 30, 2022
Notes Tables  
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
  

Nine Months Ended September 30, 2022

 
          

Weighted

     
      

Weighted

  

Average

     
  

Number

  

Average

  

Remaining

  

Aggregate

 
  

of

  

Exercise

  

Contractual

  

Intrinsic

 
  

Shares

  

Price

  

Term (years)

  

Value

 

Options outstanding, January 1, 2022

  3,173,103  $7.51   9.0  $- 

Options granted

  959,000  $1.25         

Options exercised

  -            

Options canceled

  (26,397) $8.02         

Options outstanding, September 30, 2022

  4,105,706  $6.05   8.5  $80 
                 

Vested and exercisable and expected to vest, September 30, 2022

  3,895,519  $6.24   8.5  $71 
                 

Vested and exercisable, September 30, 2022

  1,521,946  $11.45   8.1  $- 
Share-Based Payment Arrangement, Option, Exercise Price Range [Table Text Block]
            

Weighted

         
    

Number

  

Weighted

  

Average

  

Number

  

Weighted

 
    

Outstanding

  

Average

  

Remaining

  

Exercisable

  

Average

 
Range of 

as of

  

Exercise

  

Contractual

  

as of

  

Exercise

 
Exercise Prices 

September 30, 2022

  

Price

  

Term (Years)

  

September 30, 2022

  

Price

 
                       
$0.66-

$1.26

  953,167  $1.25   9.3   157,712  $1.26 
$2.28-

$2.96

  2,196,021  $2.73   8.7   688,362  $2.73 
$3.06-

$3.40

  10,000  $3.20   8.5   3,771  $3.20 
$4.45-

$4.80

  11,900  $4.72   8.2   5,319  $4.71 
$5.10-

$5.40

  88,000  $5.28   8.0   63,250  $5.34 
$6.90-

$6.90

  5,400  $6.90   7.5   3,376  $6.90 
$8.60-

$8.91

  822,332  $8.69   7.1   583,220  $8.69 
$10.90-

$13.60

  15,500  $12.64   7.4   13,553  $12.89 
$380.00-

$9,920.00

  3,386  $2,869.31   5.5   3,383  $2,870.91 
Total: 

 

  4,105,706  $6.05   8.5   1,521,946  $11.45 
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
  

Three Months Ended

  

Nine Months Ended

 
  

September 30,

  

September 30,

 
  

2022

  

2021

  

2022

  

2021

 
                 

Expected term (in years)

  6   5   6   6 

Average volatility

  89%  84%  88%  76%

Risk-free interest rate

  2.69%  0.81%  1.46%  0.97%

Dividend yield

  0%  0%  0%  0%
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
  

Three Months Ended

  

Nine Months Ended

 
  

September 30,

  

September 30,

 
  

2022

  

2021

  

2022

  

2021

 
                 

Cost of revenue

 $64  $76  $193  $191 

Research and development

  118   131   361   330 

Selling, general and administrative

  686   881   2,183   2,244 

Total

 $868  $1,088  $2,737  $2,765