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Note 12 - Summary of Stock Options (Tables)
6 Months Ended
Jun. 30, 2022
Notes Tables  
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
  

Six Months Ended June 30, 2022

 
          

Weighted

     
      

Weighted

  

Average

     
  

Number

  

Average

  

Remaining

  

Aggregate

 
  

of

  

Exercise

  

Contractual

  

Intrinsic

 
  

Shares

  

Price

  

Term (years)

  

Value

 

Options outstanding, January 1, 2022

  3,173,103  $7.51   9.0  $- 

Options granted

  955,000  $1.25         

Options exercised

  -            

Options canceled

  (4,094) $7.69         

Options outstanding, June 30, 2022

  4,124,009  $6.06   8.8  $- 
                 

Vested and exercisable and expected to vest, June 30, 2022

  3,873,550  $6.29   8.8  $- 
                 

Vested and exercisable, June 30, 2022

  1,266,335  $13.10   8.3  $- 
Share-Based Payment Arrangement, Option, Exercise Price Range [Table Text Block]
           

Weighted

         
   

Number

  

Weighted

  

Average

  

Number

  

Weighted

 
   

Outstanding

  

Average

  

Remaining

  

Exercisable

  

Average

 

Range of

as of

  

Exercise

  

Contractual

  

as of

  

Exercise

 

Exercise Prices

June 30, 2022

  

Price

  

Term (Years)

  

June 30, 2022

  

Price

 
                      
$0.71

-

$1.26 955,000  $1.25   9.5   98,024  $1.26 
$2.28

-

$2.96 2,207,000  $2.73   9.0   544,316  $2.73 
$3.06

-

$3.40 10,000  $3.20   8.7   3,146  $3.20 
$4.45

-

$4.80 11,900  $4.72   8.4   4,576  $4.71 
$5.10

-

$5.40 88,000  $5.28   8.3   62,907  $5.34 
$6.90

-

$6.90 5,400  $6.90   7.8   3,038  $6.90 
$8.60

-

$8.91 827,800  $8.69   7.4   533,718  $8.69 
$10.90

-

$13.60 15,500  $12.64   7.7   13,209  $12.94 
$380.00

-

$9,920.00 3,409  $2,878.01   5.8   3,401  $2,882.61 
Total:

 

  4,124,009  $6.06   8.8   1,266,335  $13.10 
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
  

Three Months Ended

  

Six Months Ended

 
  

June 30,

  

June 30,

 
  

2022

  

2021

  

2022

  

2021

 
                 

Expected term (in years)

  6   6   6   6 

Average volatility

  89%  83%  88%  83%

Risk-free interest rate

  2.94%  0.98%  1.45%  0.98%

Dividend yield

  0%  0%  0%  0%
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
  

Three Months Ended

  

Six Months Ended

 
  

June 30,

  

June 30,

 
  

2022

  

2021

  

2022

  

2021

 
                 

Cost of revenue

 $64  $60  $129  $115 

Research and development

  120   102   243   200 

Selling, general and administrative

  725   705   1,497   1,362 

Total

 $909  $867  $1,869  $1,677