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Note 9 - Common Stock (Tables)
9 Months Ended
Sep. 30, 2019
Notes Tables  
Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block]
           
 
 
 
 
Number of
 
           
 
 
 
 
Shares
 
           
 
 
 
 
Outstanding
 
   
Exercisable
 
Expiration
 
Exercise
   
Under
 
Issuance Date
 
for
 
Date
 
Price
   
Warrants
 
                         
October 2014
 
Common Shares
 
October 13, 2019
  $
424.00
     
288
 
November 2014
 
Common Shares
 
November 12, 2019
  $
424.00
     
125
 
February 2015
 
Common Shares
 
February 17, 2025
  $
400.00
     
754
 
March 2015
 
Common Shares
 
March 26, 2025
  $
272.00
     
14
 
May 2015
 
Common Shares
 
May 12, 2025
  $
424.00
     
362
 
May 2015
 
Common Shares
 
May 17, 2020
  $
424.00
     
215
 
December 2015
 
Common Shares
 
December 16, 2025
  $
560.00
     
267
 
April 2016
 
Common Shares
 
April 1, 2026
  $
608.00
     
250
 
May 2016
 
Common Shares
 
May 11, 2021
  $
774.00
     
50
 
June 2016
 
Common Shares
 
June 20, 2026
  $
498.00
     
1,004
 
May 2017
 
Common Shares
 
May 25, 2027
  $
950.00
     
2,220
 
   
 
 
 
   
 
     
5,549