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Note 2 - Summary of Significant Accounting Policies (Tables)
9 Months Ended
Sep. 30, 2017
Notes Tables  
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
   
Nine Months Ended
 
   
September 30,
 
   
2017
   
2016
 
                 
Stock options to purchase common stock
   
2,489,979
     
1,315,808
 
Warrants to purchase common stock
   
642,622
     
425,274
 
Restricted common stock awards
   
-
     
64,405