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Note 10 - Income Taxes (Tables)
12 Months Ended
Dec. 31, 2015
Notes Tables  
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
 
 
Year Ended

December 31,
 
 
 
2015
 
 
2014
 
                 
Income tax provision (benefit) at statutory rate
    (34 )%     (34 )%
State income taxes, net of federal benefit
    (6 )%     (6 )%
Merger transaction costs
    0 %     6 %
Change in valuation allowance
    39 %     37 %
Other
    1 %     (3 )%
Effective tax rate
    0 %     0 %
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
 
 
December 31,
 
 
 
2015
 
 
2014
 
Deferred tax assets:
               
Net operating loss carryforwards
  $ 10,726     $ 5,770  
Capitalized start up costs
    7,225       7,751  
Research and development credits
    248       189  
Accruals and reserves
    497       169  
Total deferred tax assets
    18,696       13,879  
Deferred tax liabilities:
               
Fixed assets and depreciation
    (8 )     (13 )
Valuation allowance
    (18,688 )     (13,866 )
                 
Net deferred tax assets
  $ -     $ -  
Schedule of Unrecognized Tax Benefits Roll Forward [Table Text Block]
 
 
Year Ended
December 31,
 
 
 
2015
 
 
2014
 
                 
Balance at the beginning of the year
  $ 97     $ 83  
Additions based upon tax positions related to the current year
    31       14  
Balance at the end of the year
  $ 128     $ 97