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Consolidated Statements of Cash Flows - USD ($)
12 Months Ended
Sep. 30, 2017
Sep. 30, 2016
Sep. 30, 2015
CASH FLOWS FROM OPERATING ACTIVITIES:      
Net loss $ (34,380,295) $ (81,723,002) $ (91,940,882)
(Gain) loss on disposal of fixed assets     (19,195)
Change in value of derivatives (890,362) 301,022 (2,869,267)
Contingent consideration - fair value adjustments   (5,862,464) 1,891,533
Noncash impairment expense   2,050,817  
Acquired in-process research and development     10,142,786
Stock-based compensation 7,891,595 11,595,816 10,232,897
Depreciation and amortization 4,690,440 3,260,045 2,336,207
Amortization/(accretion) of note premiums (43,519) 231,902 1,110,524
Changes in operating assets and liabilities:      
Accounts receivable 7,203 (75,000)  
Prepaid expenses and Other Current Assets 2,814,509 (1,020,734) (3,485,421)
Deferred revenue 157,981 5,000,000  
Accounts payable (3,509,995) 2,554,802 2,497,804
Accrued expenses (401,777) (871,833) 4,435,784
Other (274,752) 131,143 (40,385)
NET CASH PROVIDED BY (USED IN) OPERATING ACTIVITIES (23,938,972) (64,427,486) (65,707,615)
CASH FLOWS FROM INVESTING ACTIVITIES:      
Purchases of property and equipment (7,918,198) (3,860,237) (1,970,612)
Proceeds from sale of fixed assets     500
Purchases of marketable securities (44,974,736)    
Proceeds from sale of marketable securities 4,248,716 17,308,000 26,090,950
Cash paid for acquisitions     (10,000,000)
NET CASH PROVIDED BY (USED IN) INVESTING ACTIVITIES (48,644,218) 13,447,763 14,120,838
CASH FLOWS FROM FINANCING ACTIVITIES:      
Principal payments on notes payable (197,790) (217,549) (213,991)
Payments of taxes for net share settled restricted stock unit issuances (438,838) (634,187)  
Proceeds from the exercises of warrants and stock options 272,818 3,752,120 504,512
Proceeds from the issuance of common stock 12,419,119 52,231,433  
NET CASH PROVIDED BY (USED IN) FINANCING ACTIVITIES 12,055,309 55,131,817 290,521
NET INCREASE (DECREASE) IN CASH (60,527,881) 4,152,094 (51,296,256)
CASH AT BEGINNING OF PERIOD 85,366,448 81,214,354 132,510,610
CASH AT END OF PERIOD 24,838,567 85,366,448 81,214,354
Supplementary disclosures:      
Interest Paid (187,647) (11,287) (14,429)
Property and equipment purchased through tenant improvement allowance financing   (4,849,360)  
Property and Equipment expenditures included in accounts payable and accrued expenses   (4,801,930)  
Income Tax Credits Refunded 3,635,016 1,365,288  
Income Tax Paid $ (2,400) $ (2,400) (2,400)
Novartis      
Supplementary disclosures:      
Common Stock issued to Novartis for asset acquisition     $ (25,000,000)