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Collaboration and License Agreements - Amgen, Inc - Additional Information (Detail)
12 Months Ended
Sep. 30, 2017
USD ($)
$ / shares
shares
Nov. 18, 2016
USD ($)
Sep. 28, 2016
USD ($)
Agreement
Sep. 30, 2017
USD ($)
$ / shares
shares
Sep. 30, 2016
USD ($)
$ / shares
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]          
Proceeds from the issuance of common stock       $ 12,419,119 $ 52,231,433
Amgen          
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]          
Stock issued, price per share | $ / shares $ 7.16     $ 7.16 $ 7.16
Collaboration and License agreements | Amgen          
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]          
Agreement date Sep. 28, 2016        
Number of agreements | Agreement     2    
ARO-AMG1 Agreement | Amgen          
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]          
Additional amount of common stock shares agreed to sell upon exercise of option     $ 5,000,000    
Number of trading days, used to calculate share price of Common Stock, surrounding option exercise date     30 days    
Deferred revenue $ 5,000,000     $ 5,000,000  
Deferred revenue amortized into revenue       2,500,000  
Collaboration and License agreements          
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]          
Cash received as due under collaboration agreement     $ 35,000,000    
Collaboration and License agreements | Maximum          
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]          
Option payments, and development, regulatory and sales milestone payments.     617,000,000    
Collaboration and License agreements | Amgen          
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]          
Proceeds from the issuance of common stock     $ 21,500,000    
ARO-LPA (AMG 890) Agreement | Amgen          
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]          
Deferred revenue $ 30,000,000     30,000,000  
Deferred revenue amortized into revenue       27,300,000  
Revenue generated from work orders under services agreement       $ 1,500,000  
Common Stock Purchase Agreement | Amgen          
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]          
Agreement date Sep. 28, 2016        
Shares issued | shares 3,002,793     3,002,793  
Stock issued, price per share | $ / shares $ 7.16     $ 7.16  
Proceeds from the issuance of common stock   $ 12,500,000      
Common Stock Purchase Agreement | Amgen | NASDAQ          
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]          
Number of trading days, used to calculate weighted average price of Common Stock, listed in stock market 30 days