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Concentrations of Credit Risk and Current Expected Credit Losses
12 Months Ended
Dec. 31, 2021
Concentrations of Credit Risk and Current Expected Credit Losses  
Concentrations of Credit Risk and Current Expected Credit Losses

Note 4. Concentrations of Credit Risk and Current Expected Credit Losses

In November 2009, we entered into a collaboration and license agreement with Novartis. In December 2009, we entered into a license, development and commercialization agreement with Lilly. In December 2018, we entered into a research collaboration and licensing agreement with Innovent Biologics, Inc. (“Innovent”). In July 2019, we entered into a collaboration and license agreement with Zai Lab (Shanghai) Co., Ltd., a subsidiary of Zai Lab Limited (collectively, “Zai Lab”). The above collaboration partners comprised, in aggregate, 36% and 42% of the accounts receivable balance as of December 31, 2021 and 2020, respectively. For further information relating to these collaboration and license agreements, refer to Note 6.

In November 2011, we began commercialization and distribution of JAKAFI, in April 2020, we began commercialization and distribution of PEMAZYRE and in October 2021, we began commercialization and distribution of OPZELURA to a number of customers. Our product revenues are concentrated in a number of these customers. The concentration of credit risk related to our JAKAFI, PEMAZYRE and OPZELURA product revenues is as follows:

Percentage of Total Net

Product Revenues for the

Years Ended,

December 31,

 

2021

2020

2019

Customer A

18

%  

20

%  

20

%

Customer B

12

%  

13

%  

13

%

Customer C

18

%  

17

%  

16

%

Customer D

9

%  

11

%  

11

%  

Customer E

11

%  

10

%  

8

%

We are exposed to risks associated with extending credit to customers related to the sale of products. Customers A, B, C, D and E comprised, in the aggregate, 31% and 33% of the accounts receivable balance as of December 31, 2021 and 2020, respectively. The concentration of credit risk relating to our other product revenues or accounts receivable is not significant.

We assessed our collaborative and customer receivable assets as of December 31, 2021 according to our accounting policy for applying reserves for expected credit losses, noting minimal history of uncollectible receivables and the continued perceived creditworthiness of our third party sales relationships, upon which the expected credit losses were considered de minimis.